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1 151 (0,094s) •

Project

Lipid Cubic Phases for Drug Delivery and Nanocrystallization (GA17-00973S)

Nanoparticles for delivery of peptides, proteins and plasmid DNA will be designed for regenerative therapy purposes using lipid cubic phases (LCP). The mechanism and the structural pathway of nanoparticle formation will be ...

BO - Biofyzika

  • 2017 - 2019
    • •
  • 5 484 tis. Kč
    • •
  • 4 965 tis. Kč
    • •
  • GA ČR
Project

Involvement of nuclear phosphoinositides containing structures in gene expression (LTC20024)

nanoparticles and analysis of their composition. 2) To determine the physico-chemical properties of isolated nanoparticles and analyze their function. 3) To produce artificial PIPs containing particles mimicking properties of Nu...

Cell biology

  • 2020 - 2023
    • •
  • 8 816 tis. Kč
    • •
  • 8 816 tis. Kč
    • •
  • MŠMT
Project

*New procedures of the lipid micro- and nanodispersion systems formulation as the transport systems of pharmacological active substances (2A-1TP1/015)

*The aim of the project is to indroduce new technological procedures of lipid emulsions and solid lipid nanodispersion formulation and to utilize them as carriers of drugs mainly for per oral and topical administrations.......

JP - Průmyslové procesy a zpracování

  • 2006 - 2011
    • •
  • 15 011 tis. Kč
    • •
  • 9 201 tis. Kč
    • •
  • MPO
Project

Encapsulation of bisquaternary oxime reactivators into solid lipid nanoparticles for enhanced reactivation of cholinesterases in CNS (GA25-15339S)

of encapsulation of bisquaternary oxime reactivators into solid lipid nanoparticles...

Neurosciences (including psychophysiology)

  • 2025 - 2027
    • •
  • 13 027 tis. Kč
    • •
  • 13 027 tis. Kč
    • •
  • GA ČR
Project

Integration of novel RNA-nanotherapeutics in patient-derived breast cancer organoids (NU23J-08-00035)

and lipid nanoparticle’s formulations, tackling common clinical issues related. The flexible design of RNA molecules combined with the scalability and tunability of lipid nanoparticles, make RNA-nanotherapeutics a...

Biochemistry and molecular biology

  • 2023 - 2026
    • •
  • 6 894 tis. Kč
    • •
  • 6 894 tis. Kč
    • •
  • MZ
Project

In-silico Workflow for Lipid-Mediated Active Pharmaceutical Ingredients Delivery Systems (GA25-18467S)

Lipid-mediated active pharmaceutical ingredients (APIs) delivery systems have enormous potential for the treatment of cancer or rare diseases. Lipid nanocarriers simulations of lipid-mediated API delivery systems through cu...

Physical chemistry

  • 2025 - 2027
    • •
  • 5 109 tis. Kč
    • •
  • 5 109 tis. Kč
    • •
  • GA ČR
Project

NanoFusion - drug delivery system generator (FV40356)

The main objective of the project is to develop a novel type instrument for lipid nanoparticle preparation and analyses used in basic research, pharma industry and biomedicine. We expect the NanoFusion instrument to engage a solid p...

Polymer science

  • 2019 - 2022
    • •
  • 15 329 tis. Kč
    • •
  • 10 045 tis. Kč
    • •
  • MPO
Project

Integrated design methodology of nanoformulation processes for (trans-)dermal delivery of actives (GA19-09600S)

, lipid nanoparticles, liposomes, and dendrimers in simple and combined formulations and lipid model membranes which will imitate both the healthy and diseased skin barrier......

Pharmacology and pharmacy

  • 2019 - 2023
    • •
  • 9 552 tis. Kč
    • •
  • 9 289 tis. Kč
    • •
  • GA ČR
Project

*Development of fat emulsions for parenteral nutrition with specific pharmacological effects. (FT-TA/015)

*Development of the new types of parenteral fat emulsions with specific pharmacological effects and to work out the technologies of its preparation. The new results reflecting mechanisms of the effects of fatty acids, their metabolites and antioxidan...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2004 - 2007
    • •
  • 8 330 tis. Kč
    • •
  • 4 300 tis. Kč
    • •
  • MPO
Project

Nanotechnology Approaches for Drug Delivery Across Blood-Tissue Barriers (GAP304/11/2246)

, solubility at thesite of its absorption, relative lipid solubility etc. When a drug blood-tissue barriers. The most progressive way is a novel technique of nanoparticle barriers. The specific goals of this project are preparation ...

FR - Farmakologie a lékárnická chemie

  • 2011 - 2014
    • •
  • 5 700 tis. Kč
    • •
  • 5 700 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 1 151