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1 510 (0,154s) •

Project

Prediction of changes in parameters of metabolic syndrome X related to changes of betahydroxybutate as a marker of ketegenesis in a study with physical activity at patients with metabolic syndrome X (NR8384)

The aim of this study is prediction of changes in parameters of metabolic syndrome X in study with physical activity in metabolic patients. Quantifications of relations between some parameters of metabolic syndrome X and th...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2005 - 2007
    • •
  • 3 626 tis. Kč
    • •
  • 3 588 tis. Kč
    • •
  • MZ
Project

Metabolic stress as regulator of Notch signalling (GA17-17529S)

metabolic sensors that orchestate the interplay between metabolism and other cellular processes. Metabolic stress represents conditions where nutrients, energy or oxygen to be sensitive to perturbation of glycolysis and si...

EB - Genetika a molekulární biologie

  • 2017 - 2019
    • •
  • 5 758 tis. Kč
    • •
  • 5 758 tis. Kč
    • •
  • GA ČR
Project

Metabolic reprogramming of mesenchymal stromal cells for regenerative medicine applications (GA22-31457S)

) are largely affected by energy metabolism. This project aims to solve the ambitious idea of characterizing the MSC metabolic profile to improve their regenerative abilities. As model of MSC. There, we will assess metabolic

Cell biology

  • 2022 - 2025
    • •
  • 10 127 tis. Kč
    • •
  • 10 127 tis. Kč
    • •
  • GA ČR
Project

Technocultures of extended metabolism (GA24-12497S)

in biomedical research and clinical practice relating to the human metabolism. These advances underscore the complexity and malleability of metabolisms and in fact expand qualitative methods, we examine how the metabolism ...

Sociology

  • 2024 - 2026
    • •
  • 6 644 tis. Kč
    • •
  • 6 644 tis. Kč
    • •
  • GA ČR
Project

Identification and characterization of genetic factors and pathogenetic mechanism of defects affecting de novo purine metabolism (NU23-01-00500)

Purine metabolism is integral to human life, and purines are the essential in the cell cytoplasm upon purine demand. Intermediates of purine metabolism are potent signaling molecules involved in pathogenesis of purine metabolism...

Biochemistry and molecular biology

  • 2023 - 2026
    • •
  • 9 637 tis. Kč
    • •
  • 9 637 tis. Kč
    • •
  • MZ
Project

The role of 11beta-hydroxysteroid dehydrogenase in glucocorticoid metabolism during immunomodulation (GA305/07/0328)

There is increasing recognition of the role of pre-receptor metabolism of glucocorticoids (GC) in various GS-target tissues, but our knowledge of this metabolism in lymphoid organs and immune cells is very limited. GS-metabolism...

ED - Fyziologie

  • 2007 - 2009
    • •
  • 3 164 tis. Kč
    • •
  • 3 164 tis. Kč
    • •
  • GA ČR
Project

Familial hyperlipoproteinemias and the metabolic syndrome - genotype to phenotype correlation. (NB7392)

A study of familial hyperlipoproteinemias, the metabolic syndrome and their phenotypic expressionin correlation with genotype findings. Determination of impact of the metabolic disorder on atherogenesis and the vessel wall function....

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2003 - 2005
    • •
  • 4 099 tis. Kč
    • •
  • 4 037 tis. Kč
    • •
  • MZ
Project

Oxidative metabolism in lymphocytes of obese humans (OC 918.40)

spectrum of metabolic changes. The efficiency of mitochondrial energy generating metabolism is dependent on the amount and activities of respiratory chain complexes, ATP through mitochondrial membrane. The studies on the metabo...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2000 - 2003
    • •
  • 2 901 tis. Kč
    • •
  • 1 010 tis. Kč
    • •
  • MŠMT
Project

Establishment and exploitation of human hepatocyte culture systems for the in vitro evaluation of drug metabolism (OC B15.40)

Establishment and exploitation of human hepatocyte culture systems for the in vitro evaluation of drug metabolism...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2002 - 2003
    • •
  • 1 848 tis. Kč
    • •
  • 1 271 tis. Kč
    • •
  • MŠMT
Project

Establishment and exploitation of human hepatocyte culture systems for the in vitro evaluation of drug metabolism (1P04OCB15.40)

Establishment and exploitation of human hepatocyte culture systems for the in vitro evaluation of drug metabolism...

FR - Farmakologie a lékárnická chemie

  • 2004 - 2004
    • •
  • 1 000 tis. Kč
    • •
  • 700 tis. Kč
    • •
  • MŠMT
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