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1 333 (0,091s) •

Project

Multi-omics platform for the search for biological correlates of disease and the development of new diagnostic, preventive and therapeutic approaches (EH23_020/0008540)

The project aims to connect and develop the capabilities of the teams and create a multi-omics technologies platform in the BIOCEV. This platform will allow to improve the quality of research on genetic and biological correlates of ...

Other medical science

  • 2025 - 2029
    • •
  • 98 971 tis. Kč
    • •
  • 24 655 tis. Kč
    • •
  • MŠMT
Project

Pathophysiology of dystonia – role of gene-environment interaction and common pathophysiological pathways (8F20001)

clinical diagnosis of dystonia by molecular biomarkers derived from multi-omic. Multi-omic, fMRI, MEG, TMS, LFP, LTP/LTD, PAS, optogenetics and in-vivo calcium......

Other medical science

  • 2020 - 2024
    • •
  • 5 217 tis. Kč
    • •
  • 5 217 tis. Kč
    • •
  • MŠMT
Project

Detection of new hazardous micropollutants in drinking water supply system and in vitro study of the toxicity mechanisms using multi-omics approaches (GA23-06009S)

will then be subjected to a detailed study of their toxicity using multi-omics approaches...

Water resources

  • 2023 - 2025
    • •
  • 9 528 tis. Kč
    • •
  • 9 528 tis. Kč
    • •
  • GA ČR
Project

Omics as a modern tool for the detection of banned growth promoters in fattening food-producing animals (QL24010272)

The project aim to find highly effective analytical tools for detecting systematic and masked misuse of prohibited growth promoters in the fattening of food-producing livestock. By developing and implementing precise multi-omics-bas...

Veterinary science

  • 2024 - 2028
    • •
  • 19 704 tis. Kč
    • •
  • 16 629 tis. Kč
    • •
  • MZe
Project

Modernization of the instrumentation and IT equipment of the National Center for Medical Genomics (EH23_015/0008183)

The purpose of the project is to upgrade of the "National Center for medical Genomics" a large research infrastructure and to build-up and strengthening of research and innovation capacities and implementation of advanced genomic technologies.......

Other medical science

  • 2024 - 2027
    • •
  • 62 738 tis. Kč
    • •
  • 15 873 tis. Kč
    • •
  • MŠMT
Project

Evolutionary trade-offs of plasmid-carried antibiotic resistance in clinically relevant pathogens (GA24-12527S)

will be examined and linked with molecular differences using an integrative multi-omics...

Microbiology

  • 2024 - 2026
    • •
  • 11 985 tis. Kč
    • •
  • 11 985 tis. Kč
    • •
  • GA ČR
Project

Interdisciplinary Approaches for the Development and Application of New Materials in Medical Practice - New Omic Technologies (EH23_021/0009224)

The project focuses on research in the field of state-of-the-art applications of omics technologies and the connection of specific methodological approaches (genomics, transcriptomics, proteomics, metabolomics and hormonomics) with a focus s...

Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])

  • 2025 - 2029
    • •
  • 68 750 tis. Kč
    • •
  • 19 800 tis. Kč
    • •
  • MŠMT
Project

Tumors with no aspartate synthesis a metabolic mystery (GA24-10167S)

for the loss of GOT1/2. To identify this pathway, we will examine GOT1/2 dKO cells by multi-omics, perform scRNAseq in tumors to reveal adaptation to GOT1/2 deficiency in vivo......

Biochemistry and molecular biology

  • 2024 - 2026
    • •
  • 9 937 tis. Kč
    • •
  • 9 937 tis. Kč
    • •
  • GA ČR
Project

Functional Genomics and Symbio-Genomics in Ticks (GM22-18424M)

physiology. Using a holistic approach that blends state-of-the-art microscopy, multi-omics data, and RNAi with a newly developed comparative model of symbiont-free ticks and bacteria, allowing the multi-species co-existenc...

Biochemistry and molecular biology

  • 2022 - 2026
    • •
  • 24 680 tis. Kč
    • •
  • 24 680 tis. Kč
    • •
  • GA ČR
Project

Spatiotemporal transcriptome and proteome analysis of α-Synuclein pathology in Parkinson’s disease Identification of cell type-specific vulnerability and tolerance mechanisms (9F24003)

1. Spatiotemporal analysis of neuronal, glial and immune cell responses at transcriptome and proteome level in vulnerable and more resistant brain regions; 2. Multi-omic bioinformatics analysis of spatiotemporal gene and protein exp...

Other medical science

  • 2024 - 2027
    • •
  • 6 633 tis. Kč
    • •
  • 6 633 tis. Kč
    • •
  • MŠMT
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