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526 (0,115s) •

Project

MWPharmASIA - database extension of drug substances and their MWPharm modelsfor East Asian population and development of NGS diagnostic panel and algorithm for predicting statin pharmacokinetics (TF05000020)

in creating MwPharmAsia, NGS panel and testing of automatic data searching robot (CIIRC) for the East Asian population. Subsequently, this PKPD models will be used to create NGS panel (New generation seqencer). Wi...

Pharmacology and pharmacy

  • 2018 - 2019
    • •
  • 8 976 tis. Kč
    • •
  • 6 623 tis. Kč
    • •
  • TA ČR
Project

Bioinformatics and functional analyses of susceptibility variants supporting the NGS-based testing of hereditary cancers in the Czech Republic (NV16-29959A)

of NGS, we will perform comprehensive reanalysis of NGS cancer panel data (obtained population specific genetic background, we will perform cancer panel NGS analysis of 1000High-throughput targeted next-g...

EB - Genetika a molekulární biologie

  • 2016 - 2019
    • •
  • 15 504 tis. Kč
    • •
  • 14 625 tis. Kč
    • •
  • MZ
Project

Development of modular bioinformatics platform for next-generation sequencing data analysis. (TJ02000133)

The main goals of proposed project are (i) establishing a comprehensive capture-based NGS panel for haematological malignancies and (ii) the consequent creation of a versatile bioinformatic tool that enables simultaneous analysis of...

Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

  • 2019 - 2021
    • •
  • 9 745 tis. Kč
    • •
  • 8 093 tis. Kč
    • •
  • TA ČR
Project

Genetics of adult-onset familial focal segmental glomerulosclerosis (FSGS) – implications for individualized therapy and successful kidney transplantation (NV19-06-00443)

transplantation. New Generation Sequencing (NGS) detects mutations in a large number of genes examination and NGS in patients and their relatives with genetic FSGS, 2) identification......

Human genetics

  • 2019 - 2023
    • •
  • 13 856 tis. Kč
    • •
  • 12 179 tis. Kč
    • •
  • MZ
Project

Differential diagnosis of cardiomypathy and cardiotoxicity in oncologic patients based on innovative molecular-diagnostic platforms (FW03010174)

, NGS). The principle is the measurement of the panel of specific microRNA polymorphisms in selected genes using the NGS method.......

Health-related biotechnology

  • 2021 - 2025
    • •
  • 34 472 tis. Kč
    • •
  • 22 515 tis. Kč
    • •
  • TA ČR
Project

Comprehensive prognostic and predictive panel for chronic lymphocytic leukemia a next-generation sequencing tool suitable for clinical practice and study of genetic architecture behind the disease (NV19-03-00091)

clonality. We presume that our NGS panel tailored for CLL can be widely adopted. For this purpose, a highly complex next-generation sequencing (NGS) tool simultaneously benefits of capture-based NGS technology ena...

Oncology

  • 2019 - 2022
    • •
  • 14 426 tis. Kč
    • •
  • 14 426 tis. Kč
    • •
  • MZ
Project

Characterization of genetic predisposition to ovarian cancer using Next Gene Sequencing analysis (NV15-27695A)

sequencing (NGS) and bioinformatics analysis. Detected alterations will be confirmed population, we will design a diagnostic gene panel for the genetic examination using targeted NGS and validate it in a group of 300 unsel...

FD - Onkologie a hematologie

  • 2015 - 2018
    • •
  • 7 982 tis. Kč
    • •
  • 7 516 tis. Kč
    • •
  • MZ
Project

BIOINFORMATICS AND FUNCTIONAL ANALYSES OF SUSCEPTIBILITY VARIANTS SUPPORTING THE NGS-BASED TESTING OF HEREDITARY CANCERS IN THE CZECH REPUBLIC (II) (NU20-03-00285)

laboratories unifying cancer predisposition analysis by CZECANCA (Czech cancer panel...

Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])

  • 2020 - 2023
    • •
  • 11 831 tis. Kč
    • •
  • 11 831 tis. Kč
    • •
  • MZ
Project

Exploring causes of the neurogenetic disorders with the newest genomic methods (NU22-04-00097)

The diagnostic yield of next generation sequencing (NGS) with a gene panel in patients with neurogenetic disorders is only 25%. In other words, up to 75 by a NGS gene panel. These methods can also detect hitherto u...

Genetics and heredity (medical genetics to be 3)

  • 2022 - 2025
    • •
  • 10 731 tis. Kč
    • •
  • 10 731 tis. Kč
    • •
  • MZ
Project

Nextlife NG (EG17_107/0012362)

Nextlife NG...

Communication engineering and systems

  • 2018 - 2021
    • •
  • 6 663 tis. Kč
    • •
  • 0 tis. Kč
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  • MPO
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