All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”
EN
ČeštinaEnglish

Filters

1 007 (0,173s) •

Project

Molecular mechanism of Na/K-ATPase function Is Na/K-ATPase a functional diprotomer? (GA204/01/0254)

The goal of the propsal is to contribute to understanding of the molecular mechanism of the transport function of Na,K-ATPase. Our recent findings suggest that Na+/K+-ATPase could work as a functional diprotomer an...

EE - Mikrobiologie, virologie

  • 2001 - 2003
    • •
  • 3 199 tis. Kč
    • •
  • 1 200 tis. Kč
    • •
  • GA ČR
Project

Interaction of fluorescein and its analogues with the sodium-potassium pump. (GPP205/11/P319)

Na+/K+-ATPase is one of the most important enzymes within metabolism of eucaryotic organisms. Modulation in the activity of the Na+/K+-ATPase, by drugs of the Na+/K+-ATPase. Moreover, these drugs ...

BO - Biofyzika

  • 2011 - 2013
    • •
  • 1 054 tis. Kč
    • •
  • 1 054 tis. Kč
    • •
  • GA ČR
Project

Determination of Na+/K+-ATPase regulatory sites (GA203/07/0564)

Na+/K+-ATPase belongs to the most important enzymes in the metabolism of the animal cells (it consumes 20-70% of ATP) and its inhibition or malfunction results species directly interact with Na+/K+-ATPase, because ...

CE - Biochemie

  • 2007 - 2009
    • •
  • 1 309 tis. Kč
    • •
  • 1 309 tis. Kč
    • •
  • GA ČR
Project

Effect of lithium on Na+/K+-ATPase activity and functional consequences of oxidative stress; from animal model to bipolar patients (GA17-07070S)

triphosphate, Na+/K+-ATPase. Dysfunction of Na+/K+-ATPase during bipolar disorder may will therefore test the properties of Na+/K+-ATPase in erythrocytes and lymphocytes isolated to acute and chr...

ED - Fyziologie

  • 2017 - 2021
    • •
  • 7 291 tis. Kč
    • •
  • 6 685 tis. Kč
    • •
  • GA ČR
Project

Interaction of cisplatin with the Na+/K+-ATPase (NT11071)

administrationare caused by the inhibition of Na+/K+-ATPase. Further, we would like to elucidate the binding sites and the mechanism of Na+/K+-ATPase inhibition) and to propose......

FR - Farmakologie a lékárnická chemie

  • 2010 - 2013
    • •
  • 2 283 tis. Kč
    • •
  • 2 283 tis. Kč
    • •
  • MZ
Project

Structure, function and dynamics of Na,K-ATPase (ME 075)

BO - Biofyzika

  • 1997 - 1998
    • •
  • 300 tis. Kč
    • •
  • 300 tis. Kč
    • •
  • MŠMT
Project

Nephrotoxicity of cisplatin ? role of the Na+/K+-ATPase (GAP301/10/0883)

that it is a consequence of the Na+/K+-ATPase inhibition by cisplatin. Our preliminary experiments revealed that cisplatin is covalently bound to large cytoplasmic loop of Na+/K+-ATPase......

CE - Biochemie

  • 2010 - 2012
    • •
  • 1 353 tis. Kč
    • •
  • 1 353 tis. Kč
    • •
  • GA ČR
Project

Molecular mechanism of interaction between the H4-H5 loop of Na+/K+-ATPase and the binding site for cardiac glycosides (IAA7011801)

Na+/K+-ATPase is transporting enzyme for Na+ and K+ across the plasma membrane which is also called a receptor for cardioactive glycosides. The binding site for cardiac glycosides was revealed to be far away from t...

BO - Biofyzika

  • 1998 - 2000
    • •
  • 1 852 tis. Kč
    • •
  • 1 075 tis. Kč
    • •
  • AV ČR
Project

Are the High and Low Affinity ATP Binding Sites of Na,K-ATPase Different or Identical? (GA204/95/0624)

CE - Biochemie

  • 1995 - 1997
    • •
  • 750 tis. Kč
    • •
  • 750 tis. Kč
    • •
  • GA ČR
Project

Effect ef magnesium ions on secondary, tertiary and quaternary structure of Na, K-ATPase (IAA5011503)

BO - Biofyzika

  • 1995 - 1997
    • •
  • 575 tis. Kč
    • •
  • 575 tis. Kč
    • •
  • AV ČR
  • 1 - 10 out of 1 007