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14 (0,063s) •

Project

Impact of direct endoglin modulation on the development of major complications of metabolic syndrome atherogenesis and non-alcoholic steatohepatitis (GA22-14961S)

dysfunction, atherogenesis, liver fibrosis, and non-alcoholic steatohepatitis (NASH or alleviate atherogenesis, liver fibrosis, and NASH. We will focus on changes in Eng signaling in relation to endothelial dysfunction atherogenesi...

Pharmacology and pharmacy

  • 2022 - 2024
    • •
  • 8 954 tis. Kč
    • •
  • 8 954 tis. Kč
    • •
  • GA ČR
Project

on the prevention of liver damage in experimental model of NASH. (NT11247)

to such stimuli could influence the course and severity of non-alcoholic steatohepatitis (NASH of NASH a role of oxidative stress and inflammatory reaction together with an effect will be evaluated in an experimetal model of NA...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2010 - 2014
    • •
  • 3 663 tis. Kč
    • •
  • 3 662 tis. Kč
    • •
  • MZ
Project

Genetic, transcriptomic and metabolic profiles of patients after liver transplantation with respect to the development of NAFLD/NASH. (NV15-26906A)

of cardiovascular disease and overall mortality. Identification of NAFLD/NASH (steatohepatitis of genes and/or pathways differentially expressed in liver tissue due to NAFLD/NASH. We, metabolic and transcriptomic markers associated...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2015 - 2019
    • •
  • 16 348 tis. Kč
    • •
  • 16 348 tis. Kč
    • •
  • MZ
Project

Nutrition-based therapy of liver disease of different origin effect of n-3 PUFA (NV15-28745A)

The project is focused on a potential beneficial effect of n-3 PUFA on liver disease of different origin (non-alcoholic steatohepatitis, NASH; parenteral nutrition mechanisms. Experimental part will be performed on rodent models (dietary ind...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2015 - 2018
    • •
  • 15 807 tis. Kč
    • •
  • 15 807 tis. Kč
    • •
  • MZ
Project

Advanced mathematical methods for dissipative evolutionary systems (GA17-04301S)

. Moreover, they can describe evolutionary Stackelberg and/or Nash equilibrium models...

BA - Obecná matematika

  • 2017 - 2019
    • •
  • 3 477 tis. Kč
    • •
  • 2 964 tis. Kč
    • •
  • GA ČR
Project

A Multivalued Approach to Optima and Equilibria in Economics (GAP402/12/1309)

and sensitivity of generalized Nash equilibrium problems and optimise the construction...

AH - Ekonomie

  • 2012 - 2016
    • •
  • 5 961 tis. Kč
    • •
  • 5 961 tis. Kč
    • •
  • GA ČR
Project

Complex lifestyle modification in the treatment of non-alcoholic fatty liver disease (NU23-01-00288)

is recommended, but no long-term control study assessing the evolution of NAFLD/NASH (non care on the parameters of NAFLD/NASH in patients with metabolic syndrome......

Endocrinology and metabolism (including diabetes, hormones)

  • 2023 - 2026
    • •
  • 14 798 tis. Kč
    • •
  • 14 798 tis. Kč
    • •
  • MZ
Project

In vitro 3-dimensional liver models to study cyanotoxin-induced chronic hepatotoxicity and liver diseases. (GA19-19143S)

disease (NAFLD) and steatohepatitis (NASH). The project will focus on the development (NAFLD), eventually accompanied with an inflammation (NASH). This research......

Public and environmental health

  • 2019 - 2023
    • •
  • 5 800 tis. Kč
    • •
  • 5 722 tis. Kč
    • •
  • GA ČR
Project

Personalized Medicine – Diagnostics and Therapy (TN01000013)

Center PerMedT is focused on applied research in diagnostics and therapy of rare and genetically determined diseases. The aim is to develop both personalized diagnostic methods as well as drug candidates/drugs which would help specific groups of pat...

Pharmacology and pharmacy

  • 2019 - 2022
    • •
  • 223 884 tis. Kč
    • •
  • 178 916 tis. Kč
    • •
  • TA ČR
Project

Personalised Medicine From Translational Research into Biomedical Applications (TN02000109)

1. To further develop a market-drive and flexible platform for the progress of existing personalized medicine (PM) products: new targeted drugs, molecular diagnostics tracers and information technology solutions into marketable products; 2. To cultiv...

Pharmacology and pharmacy

  • 2023 - 2028
    • •
  • 431 311 tis. Kč
    • •
  • 323 310 tis. Kč
    • •
  • TA ČR
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