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Projects

59 projects (0,087s)

Project

Apomorphine in the evaluation of dopaminergic function in man . (IZ2311)

9F - 9

  • 1994 - 1996
  • 205 tis. Kč
  • 300 tis. Kč
  • MZ
Project

Influence of Rehabilitation on Gait and Balance Disorders in Neurodegenerative Diseases Affecting Basal Ganglia (NV17-32318A)

This project is focused on an objective evaluation of the effect of different rehabilitation programs on postural instability and gait disturbances in patients with Huntington's disease (HD) and Parkinson's disease (PD). Patients will be assigned to ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2017 - 2021
  • 7 204 tis. Kč
  • 7 158 tis. Kč
  • MZ
Project

Biomarkers of progression and treatment response in neurodegenerative disorders (NV15-25602A)

This project is aimed at examining clinical, neuroradiological and biochemical biomarkers of Parkinson’s disease (PD), other parkinsonian syndromes and Wilson’s disease (WD). All patients will be examined using clinical scales, cognitive battery, bra...

FH - Neurologie, neurochirurgie, neurovědy

  • 2015 - 2020
  • 15 670 tis. Kč
  • 15 622 tis. Kč
  • MZ
Project

Analysis of movement disorders for the study of extrapyramidal diseases mechanisms using motion capture camera systems (NV16-28119A)

Advanced methods for image analysis may allow noninvasive objectification of movement disorders. We want to expand and validate the methods of image analysis BradykAn and TremAn that we developed for monitoring movements of the upper limbs and for me...

FH - Neurologie, neurochirurgie, neurovědy

  • 2016 - 2019
  • 8 086 tis. Kč
  • 8 086 tis. Kč
  • MZ
Project

Impulsivity phenotypes and their clinical impact in neuropsychiatric disorders (NV15-30062A)

Impulsivity is an important feature that accompanies many neuropsychiatric disorders and complicates their course and treatment. In contrast to its frequent manifestation and impact, relatively little is known about its neurobiology. Moreover, there ...

FL - Psychiatrie, sexuologie

  • 2015 - 2018
  • 10 519 tis. Kč
  • 9 911 tis. Kč
  • MZ
Project

Speech disorders and analysis of their mechanisms in Parkinson's disease and other movement disorders. (NV15-28038A)

Speech is an important indicator of motor function and movement coordination and it can be extremely sensitive to involvement in the course of neurologic diseases, particularly those affecting basal ganglia. Acoustic analysis has the unique potential...

FH - Neurologie, neurochirurgie, neurovědy

  • 2015 - 2018
  • 8 151 tis. Kč
  • 8 151 tis. Kč
  • MZ
Project

STN-DBS outcomes in Parkinson´s disease the influence of vascular, cardiovascular, metabolic, and inflammatory co-morbidities (NU21-04-00445)

Deep brain stimulation (DBS) is an established treatment for late motor symptoms in Parkinson’s disease (PD). Although DBS is generally a successful therapy, it has limitations including insufficient clinical effects and adverse side effects. The eff...

Clinical neurology

  • 2021 - 2024
  • 11 682 tis. Kč
  • 11 682 tis. Kč
  • MZ
Project

Objective investigation of distinct speech phenotypes in newly diagnosed Parkinson's disease including effects of pharmacotherapy (NV19-04-00120)

Basal ganglia play an essential role in speech control including the selection of motor programs, speech execution, and sensory feedback mechanisms. Therefore, multidimensional speech impairment due to basal ganglia dysfunction is detectable in up to...

Clinical neurology

  • 2019 - 2022
  • 10 811 tis. Kč
  • 10 811 tis. Kč
  • MZ
Project

Disorders of gait, postural stability and cognition in Parkinson's disease presymptomatic detection and targeted rehabilitation (NU20-04-00327)

Disorders of gait and stability gradually reduce quality of life in patients with Parkinson's disease (PD) and other synucleinopathies. Along with cognitive deficiency, in advanced PD they become the main survival limits, whereas dementia with Lewy b...

Neurosciences (including psychophysiology)

  • 2020 - 2024
  • 13 016 tis. Kč
  • 12 950 tis. Kč
  • MZ
Project

Investigating evolution of speech disorder in Parkinson's disease via objective acoustic analysis (NW24-04-00211)

Without validated biomarkers, there is no way to identify people at risk for Parkinson’s disease (PD) or to establish strategies for its prevention. Speech is highly susceptible to neurodegeneration. Tracking speech disorder via objective acoustic an...

Clinical neurology

  • 2024 - 2027
  • 15 260 tis. Kč
  • 15 260 tis. Kč
  • MZ
  • 1 - 10 out of 59