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7 131 (0,17s) •

Project

The role of impairment of pressure-natriuresis mechanism in the pathophysiology of angiotensin II-dependent malignant form of hypertension (NS10499)

The role of impaired pressure-natriuresis mechanism in the pathophysiology of angiotensin II-induced malignant form of hypertension will be studied.......

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2009 - 2011
    • •
  • 3 762 tis. Kč
    • •
  • 3 762 tis. Kč
    • •
  • MZ
Project

Metabolic syndrome X ontogenesis, pathophysiological mechanisms and possibilities of interventions in experimental models. (IZ4202)

Metabolic syndrome X is a very frequent disorder (e.g., in USA: 20-25% of the population) increasing the risk of atherogenesis; however, its pathophysiology is not understood due to the absence of an adequate animal model. For detailed analy...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1997 - 1999
    • •
  • 2 068 tis. Kč
    • •
  • 1 580 tis. Kč
    • •
  • MZ
Project

Pathophysiology of dystonia – role of gene-environment interaction and common pathophysiological pathways (8F20001)

in molecular neurobiology, cellular and system pathophysiology, and behavioural and clinical neurosciences to a) explore disease mechanisms and identify common (and novel) pathophysiologic pathways from the molecular to th...

Other medical science

  • 2020 - 2024
    • •
  • 5 217 tis. Kč
    • •
  • 5 217 tis. Kč
    • •
  • MŠMT
Project

Pathophysiological mechanisms and possibilities of treatment of symptoms of metabolic syndrome X. (IZ2024)

9F - 9

  • 1994 - 1996
    • •
  • 543 tis. Kč
    • •
  • 797 tis. Kč
    • •
  • MZ
Project

Pathophysiologic mechanisms, nutritional and pharmacological treatment of cardiomyopathy in renal insufficiency. (IZ2023)

9F - 9

  • 1994 - 1996
    • •
  • 569 tis. Kč
    • •
  • 821 tis. Kč
    • •
  • MZ
Project

Towards a new era for the identification and characterisation of inborn errors of glycosylation (8F19002)

1.Combine omics approaches to solve the most elusive unsolved CDG cases; 2.Develop new ‘omics’ biomarkers for the detection, elucidation and prognosis of the disease; 3.Promote research into the pathophysiology of the disease; 4.Exploit new ...

Social biomedical sciences (includes family planning, sexual health, psycho-oncology, political and social effects of biomedical research)

  • 2019 - 2022
    • •
  • 3 843 tis. Kč
    • •
  • 3 843 tis. Kč
    • •
  • MŠMT
Project

Pathophysiology and genetics of metabolic syndrome in experimental models and humans (NR9359)

The aim of proposed project is to contribute to yet incomplete knowledge about genetic and pathophysiological mechanisms of metabolic syndrome and diabetes and line out possibilities of rational prevention and therapy. On basis of g...

EB - Genetika a molekulární biologie

  • 2007 - 2009
    • •
  • 12 173 tis. Kč
    • •
  • 11 612 tis. Kč
    • •
  • MZ
Project

Disruption of interneurons and glia as a common pathophysiological hallmark in heuristic animal models of schizophrenia of various origins (GA19-03016S)

is unknown. Scientists often rely on animal models when probing mechanisms of the disease with different mechanisms of action. We will use multidisciplinary methods of various neuronal and glial dysfunctions as expected proximate <...

Neurosciences (including psychophysiology)

  • 2019 - 2022
    • •
  • 9 931 tis. Kč
    • •
  • 9 601 tis. Kč
    • •
  • GA ČR
Project

Syndrome of insulin resistance, underlying mechanism, the role of role of free fatty acids, relation to age. (NB4876)

The syndrome of insulin resistance is a freguent disorder increasing the risk for the development of atherosclerosis. The pathophysiological mechanisms of the syndrome are not completely understood, because a pertinent experimental ...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1998 - 2000
    • •
  • 3 125 tis. Kč
    • •
  • 2 413 tis. Kč
    • •
  • MZ
Project

Molecular pathophysiology of erythroid disorders (LH15223)

The project aim is to discover new molecular mechanisms and mutations in selected congenital disorders of erythropoiesis. The project proposal has two stages: a) basic research including study of the molecular mechanisms leading to ...

EB - Genetika a molekulární biologie

  • 2015 - 2017
    • •
  • 1 999 tis. Kč
    • •
  • 1 999 tis. Kč
    • •
  • MŠMT
  • 1 - 10 out of 7 131