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1 697 (0,154s)

Project

Advanced macromolecular vaccines for the treatment of infectious and neoplastic diseases (LTAUSA18173)

and polymer chain architecture as well as the chemical conjugation of both vaccine components to the macromolecular carriers with respect to the vaccine immunogenicityAim of this project consists in development of advanced...

Organic chemistry

  • 2019 - 2022
  • 5 880 tis. Kč
  • 5 880 tis. Kč
  • MŠMT
Project

Polymer vaccines novel high potent immunostimulants for infectious disseases treatment (GJ16-14957Y)

hydrophilic polymer carriers which enable defined and non-destructive binding of both, an antigen and the TLR-agonists. Such polymer vaccines provide better solubility, lowerSafe and efficient vaccine requires, ex...

CD - Makromolekulární chemie

  • 2016 - 2018
  • 4 624 tis. Kč
  • 4 624 tis. Kč
  • GA ČR
Project

Personalized macromolecular vaccines agains cancer diseases (GA19-08176S)

and polymer chain architecture as well as the chemical conjugation of both vaccine components to the nanoparticle platforms with respect to the vaccine immunogenicity polymers and colloid systems for the delivery ...

Polymer science

  • 2019 - 2023
  • 4 613 tis. Kč
  • 4 589 tis. Kč
  • GA ČR
Project

Polymer prodrugs acting as endogenous vaccines for synergic tumor therapy using immunomodulation and immune checkpoint blockade (GA17-08084S)

, benefiting from chemotherapy based on novel polymer prodrugs acting as endogenous vaccines, inhibition of suppressive activity of myeloid-derived suppressor cells (MDSC of physico-chemical and biological properties of micellar

FD - Onkologie a hematologie

  • 2017 - 2021
  • 8 334 tis. Kč
  • 8 010 tis. Kč
  • GA ČR
Project

Bio-responsive polycationic vectors for genetic vaccine delivery (GA24-10980S)

Vaccines based on RNA or DNA (genetic vaccines), encoding microbial or tumor antigens, represent a new generation of immunotherapeutics for the treatment of infectious and neoplastics diseases. However, their limiting factor is the ...

Polymer science

  • 2024 - 2026
  • 4 956 tis. Kč
  • 4 956 tis. Kč
  • GA ČR
Project

Parents' and lay public attitudes towards vaccination Evaluation and intervention to promote confidence in vaccinations (NU20-09-00454)

Vaccine hesitancy has been growing worldwide. The WHO has recently named vaccine hesitancy among top ten threats to public health. Maintaining public confidence in the safety and utility of vaccines is particularly challeng...

Public and environmental health

  • 2020 - 2023
  • 6 734 tis. Kč
  • 6 734 tis. Kč
  • MZ
Project

African swine fever vaccine development (EI22_002/0000658)

swine fever vaccine. The goal is to develop a functional sample of the vaccine without the limitations typical of the recombinant vaccines. According to the chosen methodology, we will avoid the main problems of pre-existi...

Veterinary science

  • 2023 - 2026
  • 36 398 tis. Kč
  • 0 tis. Kč
  • MPO
Project

Development of a sublingual mucosal immunization technology platform for needle-free vaccination (7D19003)

Development of sublingual delivery module Development of vaccine formulation In vitro testing of vaccine formulation In vivo testing of vaccine formulation Laboratory analysis of immunity Project IP and management......

Health-related biotechnology

  • 2019 - 2022
  • 20 110 tis. Kč
  • 8 871 tis. Kč
  • MŠMT
Project

Optimal vaccination scheme with a live attenuated Salmonella Enteritidis vaccine for long lasting protection of poultry (TA04011004)

The main aim of this project is an optimal vaccination scheme leading to a long vaccination scheme will be selected based on experimental vaccinations and challenges of vaccination scheme will include oral and aero...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2014 - 2017
  • 20 745 tis. Kč
  • 13 220 tis. Kč
  • TA ČR
Project

Development of a new vaccine against Staphylococcus aureus (EI22_002/0000585)

The aim of the project is the development of a vaccine against Staphylococcus. The prepared vaccine does not use either cell antigens or cell wall proteins or a live vaccines developed against staphylococci, as antigenic co...

Pharmacology and pharmacy

  • 2023 - 2026
  • 34 033 tis. Kč
  • 0 tis. Kč
  • MPO
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