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Projects

6 367 projects (0,14s) •

Project

Effect of protein hydration shell on the stability of protein complexes. (GPP205/12/P729)

, but plays an active part in determining the structure and dynamics of both proteins and protein complexes. However, the exact molecular details of water contribution to protein-protein binding are not ye...

CF - Fyzikální chemie a teoretická chemie

  • 2012 - 2017
    • •
  • 2 037 tis. Kč
    • •
  • 2 037 tis. Kč
    • •
  • GA ČR
Project

Optical imaging of single protein dynamics (LL1602)

and tracking the conformational dynamics of proteins at a single-molecular level in molecular biology and biophysics for studying protein dynamics including fast folding the conformations of a protein in ...

CF - Fyzikální chemie a teoretická chemie

  • 2016 - 2021
    • •
  • 40 738 tis. Kč
    • •
  • 40 738 tis. Kč
    • •
  • MŠMT
Project

Multiscale methods for simulations of unstructured proteins (LUC24136)

of protein dynamics on the basis of the prediction of its structure by AlphaFold-grained models of protein dynamics. These models will be used to build a map of the conformational space of the protein. Fi...

Biochemistry and molecular biology

  • 2024 - 2026
    • •
  • 2 660 tis. Kč
    • •
  • 2 660 tis. Kč
    • •
  • MŠMT
Project

Methods of Identification and Visualization of Tunnels for Flexible Ligands in Dynamic Proteins (GA17-07690S)

behavior in proteins under molecular dynamics is one of the most important current will work for flexible ligands moving in dynamic proteins.Proteins are biochemical macromolecules, performing crucial fun...

JC - Počítačový hardware a software

  • 2017 - 2019
    • •
  • 6 205 tis. Kč
    • •
  • 5 251 tis. Kč
    • •
  • GA ČR
Project

Analysis and Visualization of Protein Structures (GAP202/10/1435)

In the project, new analytic methods for biochemical research of proteins will be developed and tested. The geometrical properties of dynamic protein models will be explored to find and asses the channels connecting an acti...

IN - Informatika

  • 2010 - 2012
    • •
  • 4 010 tis. Kč
    • •
  • 4 010 tis. Kč
    • •
  • GA ČR
Project

Biochemical and biophysical characterization of protein-protein interactions and their dynamics (GA204/01/1001)

The aim of this proposal is to better understand the molecular mechanisms of action of the selected oligomeric enzymes. To achieve this goal, the structure and dynamics of subunit-subunit interactions will be investigated, combining approach...

EE - Mikrobiologie, virologie

  • 2001 - 2003
    • •
  • 3 944 tis. Kč
    • •
  • 2 340 tis. Kč
    • •
  • GA ČR
Project

Molecular modeling of RNA molecules and their complexes the role of structural dynamics (GA20-16554S)

dynamics, local substates and partial disorder mainly in protein/RNA recognitionExplicit solvent molecular dynamics simulations will be carried out for a broad spectrum of protein/RNA complexes and RNA molecules, ...

Biochemistry and molecular biology

  • 2020 - 2022
    • •
  • 5 727 tis. Kč
    • •
  • 5 727 tis. Kč
    • •
  • GA ČR
Project

Protein computer modeling and molecular dynamics simulation (1ET400110403)

The main goal of the proposal is to develop the laboratory of the protein structure modelling and of the molecular dynamics simulation equipped with and adequate demands of other laboratories to visualize details of the protein<...

BO - Biofyzika

  • 2004 - 2007
    • •
  • 2 040 tis. Kč
    • •
  • 2 040 tis. Kč
    • •
  • AV ČR
Project

Structure and dynamics of the ribosome exit tunnel (GJ19-06479Y)

the allosteric signal and the role of nascent chain in the tunnel-protein dynamics. The main formation between amino acids. This way, a vast majority of proteins in living organisms, the newly synthesized protein ...

Biochemistry and molecular biology

  • 2019 - 2023
    • •
  • 3 611 tis. Kč
    • •
  • 3 611 tis. Kč
    • •
  • GA ČR
Project

How lipid asymmetry influences membrane protein function (GF25-19982L)

of molecular dynamics simulations, solid-state NMR spectroscopy, and scattering techniques, elucidating the structural and dynamical properties of lipids in asymmetric membranes and their interactions with integral membrane pro...

Biophysics

  • 2025 - 2027
    • •
  • 5 318 tis. Kč
    • •
  • 5 318 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 6 367