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309 (0,189s) •

Project

Analysis of QT dynamicity behaviour in relationship to the risk of sudden cardiac death (NR8060)

Changes of cardiomyocytes repolarization, expressed by changes of QT interval. A modern way to describe QT interval behaviour is QT dynamicity - QT/RR relationship. The project assess QT ...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2004 - 2006
    • •
  • 1 095 tis. Kč
    • •
  • 1 042 tis. Kč
    • •
  • MZ
Project

Bližší detailed stratification of the syndrome of prolonged QT interval. (NA5718)

One of the origins of the sudden death can be also the syndrome of the prolonged QT interval, which makes easier the rise a malignant ventricular arhytmias. The study will prove the connection with the genotypical pathology.......

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 1999 - 2003
    • •
  • 3 655 tis. Kč
    • •
  • 3 627 tis. Kč
    • •
  • MZ
Project

Autonomic provocations for the assessment of cardiac repolarization dynamics in children and the progression of sex-related differences in adolescents. (NV19-02-00197)

Presently, sex-specific normality limits of QT interval are not known will be investigated. The project will establish age- and sex-related normative QT/RR patterns and corresponding heart rate correction formulae to serve ...

Cardiac and Cardiovascular systems

  • 2019 - 2023
    • •
  • 2 965 tis. Kč
    • •
  • 2 965 tis. Kč
    • •
  • MZ
Project

Molecular genetic aspects of proarrhythmic of non-antiarrhythmic drugs. (NA7424)

QT interval prolongation and increased risk of sudden death are adverse effects of long list of widely used drugs. The fenomenon has been called the acquired long QT syndrome and its mechanism remains unclear. The congenita...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2003 - 2005
    • •
  • 2 324 tis. Kč
    • •
  • 2 119 tis. Kč
    • •
  • MZ
Project

Ventricular depolarization and repolarization analysis (GA102/08/1129)

the preceding depolarizing wave. Distance Q onset -T wave end (QT interval) is an important and short QT patient classification, and for analyzing drug influence. QT intervals are affected by heart rate <...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2008 - 2010
    • •
  • 2 999 tis. Kč
    • •
  • 2 999 tis. Kč
    • •
  • GA ČR
Project

The analysis of dynamic and static properties of QT intervals (ME09050)

The aim of this project is the dynamic measurement and analysis of new QT parameters in a unique cohort of patients with and without known QT abnormalities. All abnormalities will be analyzed and new parameters will be tested if the...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2009 - 2012
    • •
  • 2 940 tis. Kč
    • •
  • 2 940 tis. Kč
    • •
  • MŠMT
Project

Analysis of Relationship between Electrical Activity and Blood Flow at the Heart Ventricles (GAP102/12/2034)

is to reveal and confirm physiological origin of immediate change of QT intervals as a reaction on sudden change of heart rate and the following slow adaptation of QT of preprocessed biosignals to study QT int...

JA - Elektronika a optoelektronika, elektrotechnika

  • 2012 - 2016
    • •
  • 14 717 tis. Kč
    • •
  • 14 717 tis. Kč
    • •
  • GA ČR
Project

Mutation analysis of candidate genes of long QT syndrome (NR8063)

The Long QT syndrome is a genetically determined disease associated with high risk of malignant ventricular arrhytmias and sudden death. Half of the cases is caused by mutation of genes for 3 myocardial ion channels. Alteration of other ion ...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2004 - 2006
    • •
  • 2 291 tis. Kč
    • •
  • 2 042 tis. Kč
    • •
  • MZ
Project

Early prediction of arrhythmic events in patients after acute myocardial infarction. (IZ2229)

9F - 9

  • 1994 - 1996
    • •
  • 104 tis. Kč
    • •
  • 159 tis. Kč
    • •
  • MZ
Project

New methods for evaluation of repolarization homogeneity in relationship to the risk of malignant arrhythmias in patients after myocardial infarction (NR8374)

The development of cardiac repolarization assessment tends to evaluation of dynamic parameters of repolarization. Pilot studies in this field suggest good sensitivity and specificity of these parameters to reveal defects in repolarization in relation...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2005 - 2007
    • •
  • 1 397 tis. Kč
    • •
  • 1 248 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 309