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5 (0,049s)

Project

The molecules regulating osteoclast differentiation and their contribudion in rheumatoid arthritis bone resorption (NK7293)

The relation of local and systemic expression of RANKL on T lymphocytes and the RANK and RANKL ewpression on synovial tissue cells will be studied by immunohistochemisty and flow cytometry in patients with active rheumatoid arthriti...

FE - Ostatní obory vnitřního lékařství

  • 2002 - 2004
  • 3 260 tis. Kč
  • 3 246 tis. Kč
  • MZ
Project

New aspects of heterotopic ossification processes in diffuse idiopathic skeletal hyperostosis, ankylozing spondylitis, and ossification of the posterior longitudinal ligament (NK7732)

Finding some similar and different morphological signs in heterotopic ossification processes in DISH and ankylozing spondylitis. Establishing OPLL incidence in both conditions in the Czech population. Evaluation of the possible role of the RANKL<...

FE - Ostatní obory vnitřního lékařství

  • 2003 - 2005
  • 2 691 tis. Kč
  • 2 671 tis. Kč
  • MZ
Project

Angiogenesis, plasma cell kinetics, parameters of microenvironments of bone marrow and bone metabolism in monoclonal gammopathy of undetermined significance and initial phases of multiple myeloma (NR9500)

-1) and parameters of bone metabolism (RANKL/OPG, osteopontin, ICTP, PICP, NTx...

FD - Onkologie a hematologie

  • 2007 - 2009
  • 4 306 tis. Kč
  • 4 191 tis. Kč
  • MZ
Project

Cellular and molecular mechanisms in tooth-bone complex formation (GCP302/12/J059)

tooth growth and bone remodelling. Along with Rank-RankL-Opg and Fas-FasL systems...

EA - Morfologické obory a cytologie

  • 2012 - 2014
  • 4 278 tis. Kč
  • 4 278 tis. Kč
  • GA ČR
Project

Study of the role of genetic and chromosomal aberrations as part of malignant transformation of MGUS and in the course of multiple myeloma – use of the findings for diagnosis and stratification in clinical practice (NT14400)

-kappaB,DKK-1,RANKL/OPG,MIP-1alpha and HLC pairs....

FD - Onkologie a hematologie

  • 2013 - 2015
  • 7 993 tis. Kč
  • 7 830 tis. Kč
  • MZ
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