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18 (0,079s)

Project

The function of FGFR2 cilia localization in glioblastoma pathogenesis (NW24-08-00364)

, cerebral-glioblastoma GLICO organoids and RNAseq....

Oncology

  • 2024 - 2027
  • 14 710 tis. Kč
  • 14 710 tis. Kč
  • MZ
Project

Rapid Whole Genome Sequencing as a Diagnostic approach for Emergency Care and Urgent Rescue in Critilically Ill Neonates and Children (SEQCURE). (NW25-07-00217)

to perform transcriptome analysis (RNASeq) in parallel, which will help to reclassify to use methods based on rWGS and RNASeq to determine the diagnosis and elucidate......

Human genetics

  • 2025 - 2028
  • 17 414 tis. Kč
  • 17 414 tis. Kč
  • MZ
Project

Transcriptomics of Bordetella pertussis and human phagocytes interplay (GF16-34825L)

Bordetella pertussis is the causative agent of human whooping cough, a highly contagious respiratory disease that is currently again on the rise even in highly vaccinated populations. B. pertussis has been traditionally viewed as a typical extrace...

EB - Genetika a molekulární biologie

  • 2016 - 2020
  • 6 942 tis. Kč
  • 6 942 tis. Kč
  • GA ČR
Project

Alternative splicing as a regulator of auxin transport (GA16-26428S)

splicing changes subcellular localization of these hormonal regulators. In our RNAseq...

EB - Genetika a molekulární biologie

  • 2016 - 2020
  • 5 711 tis. Kč
  • 5 711 tis. Kč
  • GA ČR
Project

ADAR2-mediated RNA editing in the suprachiasmatic nucleus; focus on AMPA receptors (GA19-17037S)

RNA editing refers to posttranscriptional modifications of RNA, which fundamentally influences its maturation. Editing of adenosine to inosine is essential for the formation of functional properties of ionotropic glutamate channels that are responsib...

Neurosciences (including psychophysiology)

  • 2019 - 2023
  • 6 041 tis. Kč
  • 6 041 tis. Kč
  • GA ČR
Project

Molecular mechanisms of hormone and light signalling in shoots and roots in responses to abiotic stress (GA20-17984S)

micrografting, RNAseq and the PlantScreenTM phenotyping platform....

Plant sciences, botany

  • 2020 - 2022
  • 8 582 tis. Kč
  • 8 582 tis. Kč
  • GA ČR
Project

Identification and functional characterization of bioactive molecules produced by entomopathogenic nematodes (GA23-06457S)

using mass spectrometry, next generation sequencing – RNASeq and tests...

Biochemistry and molecular biology

  • 2023 - 2025
  • 9 987 tis. Kč
  • 9 987 tis. Kč
  • GA ČR
Project

Analysis of interactions between polyvalent Twort-like therapeutic phage and its host Staphylococcus aureus (GA18-13064S)

include co-infection RNAseq analysis suitable for transcriptome study, molecular...

Microbiology

  • 2018 - 2022
  • 7 793 tis. Kč
  • 7 052 tis. Kč
  • GA ČR
Project

Schistosoma mansoni egg-secreted proteins a comparative approach to identify bioactive molecules of a human parasite. (GA23-06638S)

The project aims to understand the modulation processes of blood fluke parasite, Schistosoma mansoni, through excretion/secretion (E/S) products taht modulate host physiological processes in favor of parasite. E/S products are generally candidate mol...

Biochemistry and molecular biology

  • 2023 - 2025
  • 10 926 tis. Kč
  • 10 926 tis. Kč
  • GA ČR
Project

Complex clinical, immunological and genetic analysis of autoinflammatory diseases (NU21-05-00522)

With their low prevalence and chronic or recurrent, clinically severe or even life-threatening course autoinflammatory diseases (AID) fulfill the European Commission definition of „rare diseases“. They represent spectrum of inflammatory conditions wh...

Immunology

  • 2021 - 2025
  • 12 080 tis. Kč
  • 12 013 tis. Kč
  • MZ
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