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Projects

7 487 projects (0,1s) •

Project

Receptor-specific radiopharmaceuticals for imaging and therapy of cancers (GA305/07/0535)

Receptor imaging with radiolabelled receptor-specific peptides has proven and biodistribution of new radiolabelled receptor-specific peptides for diagnosis or treatment of somatostatin (o...

FR - Farmakologie a lékárnická chemie

  • 2007 - 2009
    • •
  • 2 670 tis. Kč
    • •
  • 2 670 tis. Kč
    • •
  • GA ČR
Project

Study of pharmacokinetics and biodistribution of radiolabelled biologically active peptides in laboratory animals (OC B12.001)

The aim of this project is to receive new knowledge about preparation and biological behaviour of the radiolabelled receptor-specific peptides with the intention the affinity of peptides under study to specific...

FR - Farmakologie a lékárnická chemie

  • 2001 - 2004
    • •
  • 5 106 tis. Kč
    • •
  • 1 752 tis. Kč
    • •
  • MŠMT
Project

Research and development of diagnostic and therapeutic radionuclidic preparations based on monoclonal antibodies and synthetic peptides (FD-K/112)

Development and production of new type of radiopharmaceuticals based on use of specific quality of peptides and monoclonal antibodies to be bound to receptors of organs and especially tumours. Modern biotechnologies are sup...

CH - Jaderná a kvantová chemie, fotochemie

  • 2001 - 2003
    • •
  • 10 545 tis. Kč
    • •
  • 4 600 tis. Kč
    • •
  • MPO
Project

Neuropeptide FF-2 receptor as a potential anti-obesity target Impact of new analogs of RF-amide peptides (GA21-03691S)

and energy expenditure. This project deals with two RF-amide peptides, prolactin-releasing peptide (PrRP) and neuropeptide FF (NPFF), and their receptors GPR10 and NPFF peptide analogs on individual receptors<...

Physiology (including cytology)

  • 2021 - 2023
    • •
  • 11 297 tis. Kč
    • •
  • 10 676 tis. Kč
    • •
  • GA ČR
Project

Possibility of modification of nephrotoxicity of radiopharmaceuticals from the group of somatostatin analogs (NR9208)

of radiolabelled somatostatin receptor-specific peptides in nuclear medicine.The targeted radionuclide therapy using radiolabelled somatostatin receptor-specific peptides is a used and developing...

FR - Farmakologie a lékárnická chemie

  • 2007 - 2009
    • •
  • 2 229 tis. Kč
    • •
  • 2 229 tis. Kč
    • •
  • MZ
Project

Radiolabelled neuropeptides for cancer diagnosis and treatment (GAP304/10/1738)

behavior of new radiolabeled receptor-specific peptides (derivatives of somatostatin imaging and therapy of cancers and their metastasis because neuropeptide receptors are overexpressed in numerous human cancer ce...

FR - Farmakologie a lékárnická chemie

  • 2010 - 2012
    • •
  • 2 190 tis. Kč
    • •
  • 2 190 tis. Kč
    • •
  • GA ČR
Project

The effect of non-peptide angiotensin II receptor antagonist on experimental ischemic renal injury (IZ4174)

The study follows the aim to survey possibilities of pharmacological influence on renal ischemic injury in rats by means of non-peptide angiotensin II receptor antagonist and to try to find an optimum schema for its use within clini...

FJ - Chirurgie včetně transplantologie

  • 1997 - 1999
    • •
  • 2 127 tis. Kč
    • •
  • 1 823 tis. Kč
    • •
  • MZ
Project

Selection of diagnostic markers of the long-term effect of multifunctional peptide agonists and antagonists targeting µ-, δ- and κ-opioid receptors – search for new possibilities for treatment (LTAUSA18110)

The aim of this project is to test the effect of multifunctional peptides targeting µ-, δ- and κ-opioid receptors on the level of µ-, δ- and κ-opioid receptors will be exposed or un-exposed to these multifunctional pept...

Biochemistry and molecular biology

  • 2019 - 2022
    • •
  • 4 982 tis. Kč
    • •
  • 4 982 tis. Kč
    • •
  • MŠMT
Project

Lipidized analogs of prolactin-releasing peptide as potential agents for obesity therapy search for mechanism of action (GA18-10591S)

Anorexigenic neuropeptides such as prolactin-releasing peptide (PrRP that lipidized PrRP analogs bound to PrRP receptor GPR10, decreased body weight administration. Our preliminary results suggested possible involvement of recep...

Endocrinology and metabolism (including diabetes, hormones)

  • 2018 - 2020
    • •
  • 10 641 tis. Kč
    • •
  • 9 249 tis. Kč
    • •
  • GA ČR
Project

Acute and chronic effects of non-peptide angiotensin II receptor antagonist and angiotensin converting enzyme inhibitor on blood pressure,insulin sensitivity an (IZ3059)

FR - Farmakologie a lékárnická chemie

  • 1995 - 1997
    • •
  • 1 008 tis. Kč
    • •
  • 955 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 7 487