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444 (0,097s)

Project

Oxidative damage to retina and eys during hypoxia and hyperoxia (IZ4009)

Oxidative damage to retina and eye lens induced by hypoxia and hyperoxia in laboratory rat will be investigated at the level of lipids,structual proteins,and metabolic activity.The goal is to elucidate the mechanismus of cataract and retinop...

FF - ORL, oftalmologie, stomatologie

  • 1997 - 1999
  • 816 tis. Kč
  • 816 tis. Kč
  • MZ
Project

Phenotypes of axonal injury in multiple sclerosis based on in vivo measures of retinal pathology using optical coherence tomography (NT13239)

tomography. OCT technology allows not only imaging of the whole retina, but also of phenotypes of axonal injury in retina and will allow us to 1) identify which parameters of OCT are most sensitive to axonal changes in retina

FH - Neurologie, neurochirurgie, neurovědy

  • 2012 - 2015
  • 5 259 tis. Kč
  • 5 259 tis. Kč
  • MZ
Project

Role of retinal neural activity in pathogenesis of autoimmune uveitis (GJ18-11795Y)

of the choroid and retina that results in blindness. Disruption of blood-retinal barrier (BRB hypothesis that regional neural activity in the retina induces inflammatory phenotype in the retina. Because light intensity det...

Neurosciences (including psychophysiology)

  • 2018 - 2022
  • 6 279 tis. Kč
  • 5 975 tis. Kč
  • GA ČR
Project

Support of glaucoma diagnostics via advanced analysis of retinal image data (MEB100909)

Detection and analysis of retina layers Segmentation of retinal layers in OCT images Texture analysis of the neural fiber layer in colour fundus images Fusion and integration of data in the form of automatically determined index of glaukoma ...

JC - Počítačový hardware a software

  • 2009 - 2010
  • 186 tis. Kč
  • 186 tis. Kč
  • MŠMT
Project

Chemogenetically Induced Sensory Noise During Adolescence A Novel Animal Model of Schizophrenia (NW25J-04-00110)

that disrupted visual signal processing at the sensory periphery (retina) leads to unstable transfection of designer receptors (DREADDs) on the retina during early subadult life......

Neurosciences (including psychophysiology)

  • 2025 - 2028
  • 6 751 tis. Kč
  • 6 751 tis. Kč
  • MZ
Project

Molecular characterization of retinal and cerebellar defects caused by mutations in splicing factor Prpf8 (GA20-04099S)

experiments revealed defects in retina and degeneration of cerebellum. We will combine to inspect primary cilia in retina and developing cerebellum to test a hypothesis......

Biochemistry and molecular biology

  • 2020 - 2022
  • 10 124 tis. Kč
  • 10 124 tis. Kč
  • GA ČR
Project

Functional analysis of hBrr2 mutations linked to retinitis pigmentosa (GPP301/12/P425)

Retinitis pigmentosa (RP) is a hereditary disease causing degeneration of retina cells that affects 1 of 4000 people worldwide. RP is caused by mutations in the retina. However, mutations of five ubiquitously expressed splicing fact...

EB - Genetika a molekulární biologie

  • 2012 - 2018
  • 2 326 tis. Kč
  • 2 326 tis. Kč
  • GA ČR
Project

Pars plana vitrectomy in the prophylaxy and therapy of the idiopathic macular hole. (IZ4056)

Anatomical and functional results of pars plana vitrectomy with inner tamponade of the retina with expansive perfluorepropan gas and with/without autologous platelet concentrate in idiopathic macular holes of various of the disease.......

FJ - Chirurgie včetně transplantologie

  • 1997 - 1999
  • 1 700 tis. Kč
  • 1 476 tis. Kč
  • MZ
Project

Regeneration of wells - new targeted regeneration processes, regeneration and monitoring systems, and preventive diagnosis of the state of wells (TH02031034)

for the regeneration of water wells reflecting the hydrogeological conditions, the current state optimization of the regeneration process, and monitoring and evaluation of the regeneration conducted. 2. Develop a new produ...

DJ - Znečištění a kontrola vody

  • 2017 - 2020
  • 9 226 tis. Kč
  • 7 376 tis. Kč
  • TA ČR
Project

Excellent Research in Regenerative Medicine (EH22_008/0004562)

The objectives of the project are as follows: 1) Implementation of planned research projects by implementing 6 research work packages in the field of regeneration and tissue engineering. WP1 will develop new and effective treatment options ...

Neurosciences (including psychophysiology)

  • 2023 - 2028
  • 481 225 tis. Kč
  • 121 750 tis. Kč
  • MŠMT
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