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Projects

2 911 projects (0,262s)

Project

Genetic analysis of circadian and developmental genes in a new insect model (GA204/07/1032)

. eleganshave become the key genetic models of current biology. One of the recent challenges is to expand the reverse genetic techniques devised for Drosophila and C. elegans to other emerging insect genetic model,...

EB - Genetika a molekulární biologie

  • 2007 - 2011
  • 6 392 tis. Kč
  • 6 392 tis. Kč
  • GA ČR
Project

Determinants of atherosclerosis and its complications in a Czech population - their detection and management (GV306/96/K220)

on genetical factors of atherosclerotic process and non-invasive detection of premature the biochemical field attention is focused on reverse cholesterol transport. The main genetical, biochemical, preclinical and clinical...

FP - Ostatní lékařské obory

  • 1996 - 2001
  • 8 554 tis. Kč
  • 6 440 tis. Kč
  • GA ČR
Project

Architecture of an Ancestral Insect Clock – Surprising Combination of Mammalian and Drosophila Genetic Components (GC14-32654J)

represent a combination of behavioral expertise and reverse genetics and molecular with mammals. We will explore the molecular and genetic architecture of this ancestral......

EB - Genetika a molekulární biologie

  • 2014 - 2016
  • 7 778 tis. Kč
  • 7 778 tis. Kč
  • GA ČR
Project

A Reverse Genetic Approach to Study Steroid Response in Lepidopteran Insects (IAB5007002)

pathway in lepidopteran insects using the innovative reverse genetic approach of RNA-drosophilid insects are unknown due to the lack of genetic evidence. To define some genetic studies in a variety of organisms......

EB - Genetika a molekulární biologie

  • 2000 - 2002
  • 2 056 tis. Kč
  • 1 120 tis. Kč
  • AV ČR
Project

The effect of reproduction age on the sensitiveness of vascular wall to external, metabolic and genetic cardiovascular risk factors, longitudinal population study (NS10511)

of atherosclerotic changes in women is menopausal transition depending of genetic, metabolic), metabolic (mainly indicators of decreased insulin resistance and reverse cholesterol transport) and new genetic (length of telo...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2009 - 2011
  • 6 163 tis. Kč
  • 6 139 tis. Kč
  • MZ
Project

Is insect TAIMAN conserved clock protein? (GA25-17888S)

in the clock by using tools of reverse genetics. The mechanism of TAI clock actionOrganisms orchestrate their physiology with environmental changes by using their circadian clock, which is a time-measuring device conserved at a

Biochemistry and molecular biology

  • 2025 - 2027
  • 6 480 tis. Kč
  • 6 480 tis. Kč
  • GA ČR
Project

Functional analysis of lepidopteran circadian clock using reverse genetic approach (IAA5007205)

Our studies suggest that there are striking differences in the circadian timing systems even among holometaboulous insects (the fruitfly and lepidopteran moth). Here we propose to investigate the differences in the molecular regulation of the clock g...

EB - Genetika a molekulární biologie

  • 2002 - 2006
  • 5 772 tis. Kč
  • 3 285 tis. Kč
  • AV ČR
Project

Novel treatment of genetically determined metabolic disease, type 1 diabetes, using an immunotherapeutical approach. (2B08066)

The aim of the proposed project is a characterization of genetical profile of patients with type 1 diabetes mellitus (T1D) and induction of specific immune tolerance. Immunotherapeutical approaches could achieve complete cure of T1D or r...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2008 - 2011
  • 44 736 tis. Kč
  • 38 751 tis. Kč
  • MŠMT
Project

Identification of new diagnostic/predictive biomarkers and compounds applicable to personalized treatments of multidrug resistant tumors (LTC19020)

The aim of this project is identification and validation of new prognostic and predictive molecular biomarkers of multidrug resistence in solid tumors. New molecular biomarkers will be characterized in detail by analysis of genetic variabil...

Human genetics

  • 2019 - 2022
  • 3 936 tis. Kč
  • 3 936 tis. Kč
  • MŠMT
Project

Functional Analysis of Drosophila Timeless Protein (GA22-10088S)

Circadian clocks are an essential adaptation of nearly all organisms, including humans, used for synchronization with the external environment. Here, we will use a combination of evolutionary comparisons, in vitro interaction assays, and functional <...

Biochemistry and molecular biology

  • 2022 - 2025
  • 9 952 tis. Kč
  • 9 952 tis. Kč
  • GA ČR
  • 1 - 10 out of 2 911