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69 (0,25s)

Project

Determination of SNP and DNA methylation profiles in patients with myelodysplatic syndrome by microarrays. (NS9634)

Annotation 1: The aim of the project is determination of SNP and DNA methylation profiles in MDS patients. Annotation 2: We will use Illumina microarrays, "Cancer SNP Panel" for detection of 1421 SNPs located in 408 genes a...

EB - Genetika a molekulární biologie

  • 2008 - 2011
  • 5 986 tis. Kč
  • 5 986 tis. Kč
  • MZ
Project

The role of genetic variation in key molecules of Th17 immune response in individual susceptibility to prosthetic joint infection (GP310/09/P377)

). This project aims at investigating single nucleotide polymorphisms (SNP) within key molecules of Th17 immune response in PJI. The SNPs in genes coding for IL-4, 17, 35, 12B levels of selected cytokines with the most relevant ...

EC - Imunologie

  • 2009 - 2011
  • 996 tis. Kč
  • 996 tis. Kč
  • GA ČR
Project

The role of genetic variations in microRNA genes and in microRNA binding sites in colorectal cancer in relation to personalized therapy (NV15-26535A)

in colorectal cancer (CRC). Single nucleotide polymorphisms (SNPs) in miRNA genes and in 3 outcome. Our recent results on the effect of SNPs in miRNA binding sites of DNA repair genes provided the rationale to expand the study on <...

EB - Genetika a molekulární biologie

  • 2015 - 2018
  • 6 414 tis. Kč
  • 6 414 tis. Kč
  • MZ
Project

Improvement of national-wide genomic evaluation of dairy cattle by including cows with domestic production records into genotyped reference population (QK1810253)

Improvement of reliability of national-wide evaluation of dairy cattle by increasing of reference population with SNP genotyping of cows with domestic production. Connected are economic optimazation of sampling sources of DNA in herds for ch...

Animal and dairy science; (Animal biotechnology to be 4.4)

  • 2018 - 2022
  • 12 913 tis. Kč
  • 12 913 tis. Kč
  • MZe
Project

Fine association mapping of the porcine chromosome 2q region influencing meat quality and study of positional candidate genes (GAP502/10/1216)

proposal is fine multimarker association mapping of this chromosome region using SNPs. In the first period about 25 evenly spaced gene-tagged SNPs will be developed. Genotyping and association analyses of these SNPs will b...

GI - Šlechtění a plemenářství hospodářských zvířat

  • 2010 - 2012
  • 3 889 tis. Kč
  • 3 889 tis. Kč
  • GA ČR
Project

Polymorphism of the androgen receptor gene (SNP rs6152) relationship to expression of the androgen-sensitive genes in benign prostatic hyperplasia, carcinoma of the prostate and androgenetic (NS9940)

The below mentioned hypotheses will be tested using appropriate prospective as well as retrospective sample of patients with BPH, CaP and AGA. AR gene polymorphism (SNP rs6152) can have impact not only on incidence but also on course from ra...

FD - Onkologie a hematologie

  • 2008 - 2011
  • 4 883 tis. Kč
  • 4 510 tis. Kč
  • MZ
Project

Fragment and quantitative profiling of cell free fetal nucleic acids from maternal plasma in pathological and physiological pregnancies (NS9624)

Project is mainly oriented on testing of correlation between quantity and quality (size) of free fetal NA in maternal plasma during pregnancy at pathologies and normal controls. Data from analysis of STR loci, SNPs and gonozomal sequences wi...

EB - Genetika a molekulární biologie

  • 2008 - 2011
  • 3 225 tis. Kč
  • 2 954 tis. Kč
  • MZ
Project

Immunity-related genes in Equids genetic diversity and comparative genomics (GA523/06/1402)

will be typed and new genes and SNPs will be sought. Comparative approach will be used for identifying conserved genes in Equids. The genes will be analyzed for SNPs and mapped, ehrlichiosis, melanoma). Candidate genes would then b...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2006 - 2008
  • 3 764 tis. Kč
  • 3 764 tis. Kč
  • GA ČR
Project

Comparative immunogenomics of the family Equidae (GA523/09/1972)

. Furthermore, comparative analysis of single nucleotide polymorphisms (SNPs) in selected will be cloned and sequenced. SNPs identified will be used for evaluating the extent......

GI - Šlechtění a plemenářství hospodářských zvířat

  • 2009 - 2012
  • 6 886 tis. Kč
  • 6 886 tis. Kč
  • GA ČR
Project

Evaluation of genomic diversity of honey bees in relation to the health status of their populations in the Czech Republic (QK22020324)

and microsatellites). Search for SNPs in bee populations in the Czech Republic in selected and optimize panels of microsatellite and SNP markers. Evaluation of diversity and genetic......

Animal and dairy science; (Animal biotechnology to be 4.4)

  • 2022 - 2024
  • 5 760 tis. Kč
  • 5 760 tis. Kč
  • MZe
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