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Projects

42 projects (0,124s)

Project

Molecular and functional perturbances of STAT/SOCS signaling pathways in breast cancer cells and their biological consequences. (GA301/06/0912)

The signal transducers and activators of transcription (STATs) and their endogenous inhibitors of SOCS family (suppressors of cytokine signaling) are major genes in thenucleus. Various STAT/SOCS abnormalities have been found in canc...

FD - Onkologie a hematologie

  • 2006 - 2008
  • 3 931 tis. Kč
  • 3 931 tis. Kč
  • GA ČR
Project

Analysis of expression of STAT, JAK and SOCS in glial tumors of brain and in carcinomas of breast and prostate gland. Correlation with grading, expression of steroid receptors and expression (1A8244)

Disruption of signaling of JAK/STAT/SOCS may be the cause of failure of immune surveillance and may participate in development and invasion of various tumors, including carcinomas of prostate gland, breast and glial tumors of brain. The aim ...

EB - Genetika a molekulární biologie

  • 2004 - 2006
  • 1 665 tis. Kč
  • 1 419 tis. Kč
  • MZ
Project

Editing and distribution of the journal Acta Societatis Zoologicae Bohemicae (PG97169)

Editing of scientific zoological journal Acta Soc. Zool. Bohem. With 60-years tradition and its distribution (international and home). The project make it possible periodical editing four numbers a year.......

EG - Zoologie

  • 1997 - 1999
  • 932 tis. Kč
  • 537 tis. Kč
  • MŠMT
Project

Molecular and functional cancer-associated perturbances in JAK/STAT/SOCS proteins and in their target genes expression (NR8341)

The study intends to analyze molecular and functional cancer-specific abnormalities in STAT/SOCS signaling proteins and in the expression of their target genes which might represent new tumor markers and be of help in immunotherapeutic strat...

EC - Imunologie

  • 2005 - 2008
  • 12 627 tis. Kč
  • 12 366 tis. Kč
  • MZ
Project

The study of molecular defects of cancer cell in the transduction pathways of interferon signals mediated by STAT 1/SOCS 3 proteins and their significance for the prediction of tumor sensitivity (NC7139)

Project intends to explore whether and to what extend cancer-related impaired interferon transduction pathways ensured by STAT 1 and SOCS 3 protein functions The level of STAT 1/ SOCS 3 proteins, their mRNAs, and STAT 1 phosphorylat...

EC - Imunologie

  • 2002 - 2004
  • 6 107 tis. Kč
  • 6 059 tis. Kč
  • MZ
Project

Driving Spin-Orbit Coupling to Extreme (exSOC) (GF19-29614L)

Strong spin-orbit coupling (SOC) is an essential ingredient in topological) and it is the interplay of this strong electronic correlation and SOC that results in topologically is equivalent with a change of weak to strong SOC

Atomic, molecular and chemical physics (physics of atoms and molecules including collision, interaction with radiation, magnetic resonances, Mössbauer effect)

  • 2019 - 2023
  • 6 523 tis. Kč
  • 6 043 tis. Kč
  • GA ČR
Project

Loners or team players how do interactions of earthworms and other soil faunal taxa regulate soil organic carbon contents and stability? (GA24-10574S)

Earthworms can alter the amount of stabilized soil organic carbon (SOC), which and stability of SOC is scarce. Moreover, isolated consideration of earthworms unexplored effects on SOC formation and stability. In the propose...

Environmental sciences (social aspects to be 5.7)

  • 2024 - 2026
  • 8 956 tis. Kč
  • 8 956 tis. Kč
  • GA ČR
Project

SoC circuits reliability and availability improvement (GA102/09/1668)

The project deals with the basic research in the area of digital systems architectures which will allow to increase their reliablity parameters. The objective is to develop a methodology which will allow to increase safety and tolerance against failu...

JC - Počítačový hardware a software

  • 2009 - 2011
  • 4 961 tis. Kč
  • 4 961 tis. Kč
  • GA ČR
Project

Technology for improving the testability of modern digital circuits (1QS108040510)

The project aims at creating a new technology for diagnosing SoC-type digital circuits; project outputs will be a prototype and methodology. The method used for testing SoC circuits will be based on the so-called RESPIN architecture...

JC - Počítačový hardware a software

  • 2005 - 2008
  • 6 464 tis. Kč
  • 6 464 tis. Kč
  • AV ČR
Project

Electron and magnetic properties of R2T2O7 pyrochlores with strong spin-orbit coupling (GJ18-09375Y)

This project is dedicated to the study of electronic and magnetic properties of R2T2O7 pyrochlore oxides with strong spin-orbit coupling (SOC), particularly the iridates (T = Ir). The pyrochlore crystal structure together with SOC a...

Condensed matter physics (including formerly solid state physics, supercond.)

  • 2018 - 2020
  • 5 558 tis. Kč
  • 5 558 tis. Kč
  • GA ČR
  • 1 - 10 out of 42