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9 (0,092s)

Project

rTMS influence on the symptoms of obssessive compulsive disorder and panic disorder who did not respond to SSRIs. (NF7565)

Aim of study is comparison of efficacy of rTMS (used 15times during 21 days), with placebo rTMS in the SSRIs nonresponders suffering with OCD or panic disorder and evaluate efficacy of this adjuvant treatment during another 3 weeks after.......

FL - Psychiatrie, sexuologie

  • 2003 - 2005
  • 1 615 tis. Kč
  • 1 594 tis. Kč
  • MZ
Project

The effect of EEG biofeedback on symptoms of obsessive-compulsive patients who do not respond to SSRIs treatment. (NS9751)

In a double blind controlled study enrolling at least 20 patients, we will verify the effect of an innovative neurofeedback method based on independent component analysis of EEG signal on electroencephalographic characteristics and clinical symptoms ...

FL - Psychiatrie, sexuologie

  • 2008 - 2010
  • 2 740 tis. Kč
  • 2 740 tis. Kč
  • MZ
Project

Significance of genetic polymorphism for pharmacokinetics and metabolism of psychotropic drugs (IZ3428)

FL - Psychiatrie, sexuologie

  • 1996 - 1998
  • 653 tis. Kč
  • 653 tis. Kč
  • MZ
Project

The role of mTOR (mammalian target of rapamycin) pathway in the antidepressive effect of ketamine and antidepressive drugs in patient with depressive disorder translation study (NT13403)

The aim of animal part of this project is to determine whether activation (ketamine) or inhibition (rapamycin) of mTOR signaling pathway have antidepressant properties, using chronic mild stress and olfactory bulbectomy as models of depression. The r...

FH - Neurologie, neurochirurgie, neurovědy

  • 2012 - 2015
  • 9 790 tis. Kč
  • 9 790 tis. Kč
  • MZ
Project

Inprovement of coronary heart disease risk profile by treatment of latent depression. (NA7434)

Looking for a relationship of metabolic syndrome of insulin resistance and latent depression among population sample. To assess the effect of treatment by SSRI drugs on depression and some risk factors of metabolic syndrome.......

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2003 - 2005
  • 1 451 tis. Kč
  • 1 440 tis. Kč
  • MZ
Project

Dissociation and cognitive dysfunctions in outpatients with obsessive compulsive disorder - relations with treatment resistance (NR9323)

The aim of the study is to investigate, if dissociation, personality traits, cognitive dysfunction and EEG characteristics can influence the intensity of symptoms and treatment resistance in outpatients with obsessive compulsive disorder.......

FL - Psychiatrie, sexuologie

  • 2007 - 2009
  • 2 784 tis. Kč
  • 2 784 tis. Kč
  • MZ
Project

Research of anxiolytic activity of alpha2 adrenergic agonists (GP305/05/P003)

Anxiety disorders are one of the most prevalent behavioral diseases. Since the beginning of the sixties benzodiazepines become drugs of choice in anxiety, later supplemented by TCA and IMAO antidepressants and from eighties by SSRI. The ongo...

FR - Farmakologie a lékárnická chemie

  • 2005 - 2007
  • 784 tis. Kč
  • 784 tis. Kč
  • GA ČR
Project

The pathophysiological alterations in the brain after post-psychotic state and perinatal hypoxia (NU22J-04-00061)

prophylactic effect of antipsychotic risperidone and SSRI citalopram (or their combination...

Psychiatry

  • 2022 - 2025
  • 6 388 tis. Kč
  • 6 388 tis. Kč
  • MZ
Project

Dorsomedial prefrontal cortex repetitive transcranial magnetic stimulation (dmPFC-rTMS) in the augmentation of antidepressants (DOPRERA study). Efficacy, tolerability and neurophysiological changes. (NU22-04-00192)

or outpatients). We will apply AD from SSRI group in the flexible dose according to clinical...

Psychiatry

  • 2022 - 2025
  • 9 365 tis. Kč
  • 9 365 tis. Kč
  • MZ
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