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1 558 (0,116s) •

Project

Investigation of plant repetitive DNA by bioinformatic analysis of next-generation sequencing data (OC10037)

DNA sequencing is one of the basic techniques of genome investigation. However, relatively low speed and high cost of sequencing projects employing traditional, clone-based Sanger sequencing represent limiting fact...

EB - Genetika a molekulární biologie

  • 2010 - 2012
    • •
  • 3 116 tis. Kč
    • •
  • 1 494 tis. Kč
    • •
  • MŠMT
Project

Cenozoic evolution of Eurasian freshwaters reconstructed on continental scale (GA19-18453S)

of a large amount of samples by Sanger sequencing with an analysis of selected samples for a large amount of data (by next-generation sequencing). To our knowledge......

Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

  • 2019 - 2022
    • •
  • 8 273 tis. Kč
    • •
  • 8 273 tis. Kč
    • •
  • GA ČR
Project

Research of spreading, biological characteristics and harmfulness of viruses identified in strawberry using newest diagnostic methods (NGS, PCR) as a basis for legislation (QK1920245)

C001: Detection and genetic characterisation of strawberry viruses using NGS and PCR C002: Development and improvement of methods for the detection of newly identified and previously known economically important strawberry viruses C003: Strawberry vi...

Agronomy, plant breeding and plant protection; (Agricultural biotechnology to be 4.4)

  • 2019 - 2021
    • •
  • 11 687 tis. Kč
    • •
  • 11 687 tis. Kč
    • •
  • MZe
Project

ESTABLISHING GENETIC DIAGNOSIS IN CHILDREN WITH GROWTH DISORDERS USING NEXT GENERATION SEQUENCING METHODS - A PATHWAY TOWARDS INDIVIDUALIZED THERAPY (NV16-31211A)

Sanger sequencing if compared to novel next generation sequencing methods specified...

FG - Pediatrie

  • 2016 - 2019
    • •
  • 10 673 tis. Kč
    • •
  • 10 673 tis. Kč
    • •
  • MZ
Project

Individualization of therapy of rare nephropathies in children based on new molecular pathophysiology diagnostic (NV15-31586A)

syndrome (aHUS). The already established methods of diagnosis using Sanger sequencing sequencing methods (NGS) and analyze the unknown variants on protein function level......

FG - Pediatrie

  • 2015 - 2018
    • •
  • 9 584 tis. Kč
    • •
  • 9 584 tis. Kč
    • •
  • MZ
Project

Characterization of genetic predisposition to ovarian cancer using Next Gene Sequencing analysis (NV15-27695A)

sequencing (NGS) and bioinformatics analysis. Detected alterations will be confirmed by Sanger sequencing; candidate alterations of unknown significance will be tested using......

FD - Onkologie a hematologie

  • 2015 - 2018
    • •
  • 7 982 tis. Kč
    • •
  • 7 516 tis. Kč
    • •
  • MZ
Project

Evolution of aposematic patterns in large Müllerian mimetic systems (GA18-14942S)

Multiple local patterns, intraspecific polymorphism and species with their own aposematic pattern should not persist in mutualistic Müllerian mimetic systems due to the purifying and frequency dependent selection. We propose to use dated molecular ph...

Entomology

  • 2018 - 2022
    • •
  • 6 572 tis. Kč
    • •
  • 5 247 tis. Kč
    • •
  • GA ČR
Project

Prognostic impact of biomarkers and variants in susceptibility genes in systemic lupus erythematosus (NW24J-10-00024)

. In 200 patients and 100 healthy controls, we will use Sanger sequencing to analyze...

Rheumatology

  • 2024 - 2027
    • •
  • 6 831 tis. Kč
    • •
  • 6 831 tis. Kč
    • •
  • MZ
Project

Neurobiological and psychological markers of reaction to extreme stress and its impact on offspring - three generation study of holocaust survivors and their offspring (NV18-04-00559)

and Proteomics, in cooperation with Sanger Institute, Cambridge,UK....

Clinical neurology

  • 2018 - 2022
    • •
  • 10 085 tis. Kč
    • •
  • 10 066 tis. Kč
    • •
  • MZ
Project

Elateriform beetles as a model for studying the evolution of neoteny (GA22-35327S)

Beetles owe metamorphosis for their phenomenal evolutionary success. Origins of modified metamorphosis (retention of larval traits in adults) exemplified in neotenic Elateriformia are poorly supported by unstable morphological classification and ...

Entomology

  • 2022 - 2024
    • •
  • 8 605 tis. Kč
    • •
  • 6 941 tis. Kč
    • •
  • GA ČR
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