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63 (0,073s) •

Project

Analysis of substrates of Ser/Thr protein kinase StkP in Streptococcus pneumoniae and impact of phosphorylation on their function (GP204/07/P082)

Streptococcus pneumoniae is an important extra-cellular human pathogen, which causes serious invasive diseases such as pneumonia, meningitis and sepsis. Bacteria, resulting in the changes in gene expression. S. pneumoni...

EE - Mikrobiologie, virologie

  • 2007 - 2009
    • •
  • 1 452 tis. Kč
    • •
  • 1 452 tis. Kč
    • •
  • GA ČR
Project

Functions and interactions of the proteinkinase StkP substrates involved in cell division of Streptococcus pneumoniae (GA19-03269S)

Streptococcus pneumoniae is a clinically important human pathogen, responsible Ser/Thr proteinkinase StkP of S. pneumoniae is plays an important role and in this way coordinates cell division and cell wall synthesis in S. <...

Microbiology

  • 2019 - 2022
    • •
  • 5 953 tis. Kč
    • •
  • 5 953 tis. Kč
    • •
  • GA ČR
Project

The role of Ser/Thr protein kinase StkP in regulation of cell division in Streptococcus penumoniae (GAP302/12/0256)

The human pathogen Streptococcus pneumoniae is an excellent model to study eukaryotic-like protein kinases in bacteria since its genome only encodes for a single division and cell wall synthesis in S. pneumoniae. The main o...

EE - Mikrobiologie, virologie

  • 2012 - 2016
    • •
  • 7 895 tis. Kč
    • •
  • 7 895 tis. Kč
    • •
  • GA ČR
Project

Re-emergent and novel players of intracellular signalling in Streptococcus pneumoniae (GA22-11062S)

Streptococcus pneumoniae is an important human pathogen responsible for high mortality worldwide. Despite the advances in the understanding of the pneumococcal cell/Thr proteinkinase StkP of S. pneumoniae plays an important...

Microbiology

  • 2022 - 2024
    • •
  • 8 169 tis. Kč
    • •
  • 8 169 tis. Kč
    • •
  • GA ČR
Project

Determination and use of antigenic and genetic characteristics of Streptococcus pneumoniae (IZ3503)

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1996 - 1998
    • •
  • 1 946 tis. Kč
    • •
  • 1 946 tis. Kč
    • •
  • MZ
Project

Whole genome sequencing analysis of selected serotypes of Streptococcus pneumoniae causing invasive disease in the Czech Republic (NU22-09-00433)

-vaccination era, some serotypes of Streptococcus pneumoniae, despite being integrated the question of how expansive the populations of the selected serotypes of S. pneumoniae of S. pneumoniae of all serotypes stud...

Microbiology

  • 2022 - 2025
    • •
  • 7 086 tis. Kč
    • •
  • 6 460 tis. Kč
    • •
  • MZ
Project

Evolution of emergent multidrug resistant Streptococcus pneumoniae 19A serotype in era of pneumococcal vaccination. (NV16-27109A)

Pneumococcus is the major cause of pneumonia, meningitis and bacteremia. A major concern is the occurence of multidrug-resistant (MDR) pneumococci. As the pneumococcal conjugate vaccines target most of MDR serotypes, it was postulated that i...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2016 - 2019
    • •
  • 8 566 tis. Kč
    • •
  • 8 071 tis. Kč
    • •
  • MZ
Project

The role of DNA/RNA-binding proteins in cellular processes of S. pneumoniae (LUAUS25092)

Streptococcus pneumoniae is an important human pathogen that causes serious diseases and numerous deaths. The uniqueeukaryotic-type Ser/Thr protein kinase StkP and its antagonistic partner, the protein phosphatase PhpP, are critica...

Microbiology

  • 2025 - 2028
    • •
  • 7 718 tis. Kč
    • •
  • 7 718 tis. Kč
    • •
  • MŠMT
Project

Variability and composition of nasopharyngeal microbiota in receiving hematopoietic stem cell transplantation (NV17-28539A)

to infections caused by encapsulated pathogens as Streptococcus pneumoniae, which...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2017 - 2020
    • •
  • 6 549 tis. Kč
    • •
  • 6 549 tis. Kč
    • •
  • MZ
Project

Exploration of the TPP riboswitch as a new target for antibiotics (8F19007)

1. Explore the TPP riboswitch as a target for antibiotics, in particular for key ESKAPE pathogens and Streptococcus pneumoniae 2. Develop an HTS-compatible assay to monitor TPP riboswitch transcription regulation 3. Conduct an HTS f...

Microbiology

  • 2019 - 2023
    • •
  • 2 333 tis. Kč
    • •
  • 2 333 tis. Kč
    • •
  • MŠMT
  • 1 - 10 out of 63