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6 (0,064s)

Project

Survivin and livin in diagnostics and management of the bladder transitional cell cancer (NR8399)

Assessement of survivin and livin concentrations in urine with ELISA method in patients with TCC bladder cancer and healthy volunteers. Determination of cut-off concentration for survivin and livin. Assessment of recurrence risk for...

FD - Onkologie a hematologie

  • 2005 - 2007
  • 195 tis. Kč
  • 195 tis. Kč
  • MZ
Project

The role of proteins from Bir/Survivin family of genes in regulation of transcription by RNA polymerase II. (GA301/03/0333)

homologue ofhuman Survivin is participating on transcription regulation. This is an unexpected and potentially very important observation. Bir-1/Survivin are likely disassembly during transcription regulation. Survivin was...

EA - Morfologické obory a cytologie

  • 2003 - 2005
  • 4 776 tis. Kč
  • 4 776 tis. Kč
  • GA ČR
Project

The role of proteins BIR-1/Survivin in regulation of development and gene expression (GA304/07/0529)

The protein Survivin is expressed in most human cancers while its expression is low or almost undetectable in adult non-proliferating cells. In our previous work, we showed that the C. elegans homologue, BIR-1, regulates transcription of BIR...

EA - Morfologické obory a cytologie

  • 2007 - 2009
  • 4 926 tis. Kč
  • 4 926 tis. Kč
  • GA ČR
Project

New molecular markers of residual disease in acute myeloid leukemia patients and of disease progression in myelodysplastic patients, and prediction of STI-571 responsiveness in chronic myeloid leukemia patients at molecular level. (NR8748)

New molecular markers of residual disease in acute myeloid leukemia patients and of disease progression in myelodysplastic patients, and prediction of STI-571 responsiveness in chronic myeloid leukemia patients at molecular level. Genes: Wt-1, Su...

FD - Onkologie a hematologie

  • 2006 - 2009
  • 6 316 tis. Kč
  • 5 783 tis. Kč
  • MZ
Project

Study of apoptosis inhibitors as diagnostic and predictive tumor biomarkers in lung cancer (NR7860)

Analysis of expression of apoptosis inhibitors by molecular and biochemical methods in tumor tissue, lung parenchyma, biopsy and cytological samples and sputum from lung cancer patients and study of their significance as tumor biomarkers in lung canc...

FD - Onkologie a hematologie

  • 2004 - 2008
  • 9 173 tis. Kč
  • 8 553 tis. Kč
  • MZ
Project

Study of expression and activation of apoptogenic caspases and of levels of their inhibitors in non-small cell lung carcinoma (NC6610)

Study of expression and activation of apoptogennic caspases and of levels of their inhibitors XIAP and survivin in human non-small cell lung carcinoma with the aim to evaluate their correlation with progression of this cancer disease.......

FD - Onkologie a hematologie

  • 2001 - 2003
  • 3 500 tis. Kč
  • 3 470 tis. Kč
  • MZ
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