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16 (0,693s) •

Project

Genetic score in prediction of diabetes and its complications (NV18-01-00046)

to detect ndividuals at risk of development of T2DM/gestational diabetes. We study, 1400 T2DM patients, 1500 T1DM patients, 650 cases with gestation diabetes will be quantification of the genetic risk for 1/ the onset of T2DM

Endocrinology and metabolism (including diabetes, hormones)

  • 2018 - 2022
    • •
  • 12 079 tis. Kč
    • •
  • 11 987 tis. Kč
    • •
  • MZ
Project

Safety Evaluation of Adverse Reactions in Diabetes (7E12077)

In 2010 a widely marketed drug for the treatment of type 2 diabetes (T2DM of myocardial infarction, a T2DM complication it was actually supposed to prevent.This are desperately needed to monitor the benefit risk profile throughout t...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2012 - 2014
    • •
  • 1 389 tis. Kč
    • •
  • 1 389 tis. Kč
    • •
  • MŠMT
Project

Targeting senescence as a potential therapeutic approach to reduce risk of kidney damage in patients with obesity and type 2 diabetes mellitus. (NW25-01-00096)

Obesity and type 2 diabetes mellitus (T2DM) represent currently one to CKD affects approximately 40% of patients with obesity or T2DM and this percentage of systemic inflammation was suggested for patients with obesity and T2DM<...

Endocrinology and metabolism (including diabetes, hormones)

  • 2025 - 2028
    • •
  • 14 680 tis. Kč
    • •
  • 14 680 tis. Kč
    • •
  • MZ
Project

Long-term consequences of gestational diabetes for metabolic health of exposed women early postpartum significance of the new diagnostic cri (NV16-28040A)

intervention (lifestyle and/or medication) to delay or prevent T2DM onset, the possibility to quantify the risk of early postpartum transition of GDM into T2DM and subsequently......

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2016 - 2019
    • •
  • 9 950 tis. Kč
    • •
  • 9 950 tis. Kč
    • •
  • MZ
Project

Impaired Free Fatty Acids Metabolism in Obstructive Sleep Apnea Syndrome (NV15-30155A)

% of population and 50-80% of type 2 diabetes mellitus (T2DM) and obese subjects. OSA causally contributes to the development of glucose intolerance and T2DM. Our project is targeting, particularly T2DM. In contrast to prov...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2015 - 2018
    • •
  • 16 128 tis. Kč
    • •
  • 16 077 tis. Kč
    • •
  • MZ
Project

Role of diabetic milieu in selected steps of colon cancer development, its clinical outcomes and response to therapy (GA16-14829S)

prevalence the relationship between type 2 diabetes (T2DM) and colorectal cancer (CRC between CRC and T2DM and (2) clarify event. synergy of p53 and AGR2 functionality......

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2016 - 2020
    • •
  • 7 133 tis. Kč
    • •
  • 6 584 tis. Kč
    • •
  • GA ČR
Project

Mitochondrial targeting as efficient treatment of pancreatic cancer and type 2 diabetes mellitus (NV16-31604A)

Type 2 diabetes mellitus (T2DM) is widespread and has increasing incidence. Besides affecting a growing portion of the population, it is considered a pre frequent drug against T2DM is the bisguanide compound metformin. This agent is...

FD - Onkologie a hematologie

  • 2016 - 2019
    • •
  • 11 804 tis. Kč
    • •
  • 11 804 tis. Kč
    • •
  • MZ
Project

DiaCelliX - new regenerative medicine product for treatment of secondary effects of T2DM (LJ14003)

The mail aim of this project is to investigate the join effect of Adipose derivated stem cells from stromal vascular fraction and biomaterials for treatment of diabetic patients.......

EI - Biotechnologie a bionika

  • 2014 - 2016
    • •
  • 11 000 tis. Kč
    • •
  • 4 950 tis. Kč
    • •
  • MŠMT
Project

Validation of diagnostic approach in children and adolescents with randomly found hyperglycemia. (NB7420)

In about 100 children and adolescents, the cause of randomly found hyperglycemia will be estimated using metabolic investigation, estimation of autoantibodies and molecular genetic analysis. A diagnostic flowchart for clinical routine will be develop...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2003 - 2005
    • •
  • 2 341 tis. Kč
    • •
  • 2 322 tis. Kč
    • •
  • MZ
Project

Metabonomics of mouse models of obesity and lipoatrophy - studies of metabolic pathways perturbations, disease progression and therapy response (GA13-14105S)

Both type 2 diabetes (T2DM) and severe lipotrophic diabetes are associated with insulin resistance. Disturbed endocrine function of adipose tissue at obesity or its absence at lipodystrophy contributes to development of insulin resistance t...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2013 - 2016
    • •
  • 10 464 tis. Kč
    • •
  • 10 464 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 16