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26 (0,095s) •

Project

Toll-like receptors in passerine birds description, characterization of polymorphism and evolutionary consequences of allelic variation (GAP505/10/1871)

Toll-like receptors (TLRs) represent one of the basic and presumably also between TLR genes polymorphism and condition, health or sexual ornaments in wild animal populations. The proposed project aims to describe homologues of all <...

EG - Zoologie

  • 2010 - 2014
    • •
  • 7 543 tis. Kč
    • •
  • 7 543 tis. Kč
    • •
  • GA ČR
Project

The role of innate immune molecules in embryonic homeostasis and sterile inflammation (IAA500520707)

Toll-like receptors (TLRs) are involved in infectious inflammation through the recognition of microbial structures. TLRs also appear to recognize endogenous ligands recent data provide the first evidence for the expression of TL...

EC - Imunologie

  • 2007 - 2011
    • •
  • 4 832 tis. Kč
    • •
  • 4 832 tis. Kč
    • •
  • AV ČR
Project

Importance of Toll-like receptors in intestinal epithelium response to cyanobacterial water bloom (GA16-24949S)

on the interaction of microcystins with Toll-like receptors (TLRs). Interestingly, altered activation of TLRs in intestinal epithelial cells can be responsible for induction with specific TLR and can trigger inflammatory r...

DN - Vliv životního prostředí na zdraví

  • 2016 - 2020
    • •
  • 6 733 tis. Kč
    • •
  • 6 475 tis. Kč
    • •
  • GA ČR
Project

Antimicrobial peptides and Toll-like receptors in ontogeny and bacterial infections. (GA524/09/0365)

microbial antibiotics.     Toll-like receptors (TLRs) recognize various microbial of selected AMPs and TLRs will be studied by RT-PCR  in pig intestine in prenatal on the expression of AMPs and TLRs will be studied. The mo...

EC - Imunologie

  • 2009 - 2014
    • •
  • 5 860 tis. Kč
    • •
  • 5 860 tis. Kč
    • •
  • GA ČR
Project

The role of lipopolysaccharide content of the diet in the induction of oral tolerance studies in germ-free mice with modified TLR signaling (GP310/09/P182)

receptors (TLRs) and NOD receptors play an essential role in establishing mucosal the role of lipopolysaccharide, which is a TLR ligand, in the induction of oral with increased and decreased signalling via TLRs (IRAK-M and...

EC - Imunologie

  • 2009 - 2011
    • •
  • 1 292 tis. Kč
    • •
  • 1 292 tis. Kč
    • •
  • GA ČR
Project

Immune system in children with cystic fibrosis III. - factors modifying the course of the disease (NI7486)

Project...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2003 - 2005
    • •
  • 1 808 tis. Kč
    • •
  • 1 786 tis. Kč
    • •
  • MZ
Project

Polymer vaccines novel high potent immunostimulants for infectious disseases treatment (GJ16-14957Y)

Safe and efficient vaccine requires, except an antigen, using of the immunostimulatory agents, so called adjuvants. Toll-like receptor (TLR) agonists, expressed, direct application of free TLR-agonists is limited by their relatively...

CD - Makromolekulární chemie

  • 2016 - 2018
    • •
  • 4 624 tis. Kč
    • •
  • 4 624 tis. Kč
    • •
  • GA ČR
Project

Use of immune markers including expression of Toll-like receptors in early diagnosis of bacterial origin of sepsis (NR9316)

etiologic diagnosis of BS. Endotoxin of G- bacteria activates TLR-4 and CD14, whereas peptidoglycan of G+ cocci stimulates TLR-2. G- bacteria induce an early production of IL......

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2007 - 2009
    • •
  • 5 438 tis. Kč
    • •
  • 4 471 tis. Kč
    • •
  • MZ
Project

The role of TRPV1 receptors in nociceptive modulation (LH15279)

The aim of this project proposal is to study the role of TRPV1 receptors in modulation of synaptic transmission at the spinal cord level in pathological pain states. Modulatory mechanisms of TRPV1 receptors and interaction with TLR receptors...

FH - Neurologie, neurochirurgie, neurovědy

  • 2015 - 2017
    • •
  • 1 716 tis. Kč
    • •
  • 1 716 tis. Kč
    • •
  • MŠMT
Project

Cystic Fibrosis (CF) - Ineraction between CF background and infection. (NR8458)

is about TLR expression on mRNA level - the key surface cell molecules which represent...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2005 - 2009
    • •
  • 2 912 tis. Kč
    • •
  • 2 903 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 26