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676 (0,094s) •

Project

Influence of cytokines produced by TH1 and TH2 lymphocytes subpopulations on the development of endocrine autoimmune diseases (IZ4205)

Function Th1 and Th2 lymphocytes from normal or diseased individuals will be tested in tissue cultures or in non-reactive SCID mice. Influence of Th1 and Th2 lymphokines will be examined on progression or healing o...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1997 - 1999
    • •
  • 3 549 tis. Kč
    • •
  • 2 753 tis. Kč
    • •
  • MZ
Project

Influence of lymphocyte subpopulations cytokines on autoimmune endocrinopathies (GA311/98/1036)

Subpopulations CD4+ T helper lymphocytes (TH1 and TH2), based on exclusive. In proposed project TH1 and TH2 lymphocytes will be separated by cloning and each and TH2 subpopulation. The function of TH1<...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1998 - 2000
    • •
  • 2 406 tis. Kč
    • •
  • 2 334 tis. Kč
    • •
  • GA ČR
Project

Molecular characterization of autoimmune polyglandular syndromes (ME 375)

T-cells and the Th1/Th2-balance can be determined by ultrasensitive RT-PCR...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2000 - 2002
    • •
  • 1 510 tis. Kč
    • •
  • 880 tis. Kč
    • •
  • MŠMT
Project

Regulation of Th1/Th2 cytokine profile in organ transplantation (NI6843)

The aim of the proposed study os to characterize the relationship between the induction of alloreactive T lymphocytes and their capacity to produce Th1 or Th2 cytokines in mixed lymphocyte cultures (MLC) and in patients after kidney...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2001 - 2003
    • •
  • 3 813 tis. Kč
    • •
  • 3 461 tis. Kč
    • •
  • MZ
Project

Immune mechanisms in pathogenesis of periodontitis (NK6742)

The role of dental plaque bacteria and TH1 and TH2 subpopulations of lymphocytes in activation, remission, progression and prognosis of periodontitis. Influence the immunisation of dental plaque bacteria on development of experiment...

FF - ORL, oftalmologie, stomatologie

  • 2001 - 2003
    • •
  • 4 176 tis. Kč
    • •
  • 4 129 tis. Kč
    • •
  • MZ
Project

The influence of immune system dysregulation and latent toxoplasmosis on brain morphology in schizophrenia animal models and a prospective volumetric study in patients (NT13843)

. In both models Th1/TH2 cytokines, behavioral tests, volumometry, enzymes is represented by prospective morphological, Th1/Th2 cytokines and T. gondii seropositivity......

FL - Psychiatrie, sexuologie

  • 2012 - 2015
    • •
  • 8 950 tis. Kč
    • •
  • 8 950 tis. Kč
    • •
  • MZ
Project

Utilization of novel mouse strains for investigation of the NK cell regulatory role in development and therapy of cancer (GA14-10100S)

complex (NKC) exhibit high polymorphism between Balb/c (Th2-type) and C57BL/6 (Th1 cells and the changes in Th1/Th2 preferences. Investigation of this variability......

FD - Onkologie a hematologie

  • 2014 - 2018
    • •
  • 10 006 tis. Kč
    • •
  • 10 006 tis. Kč
    • •
  • GA ČR
Project

Aplication detection of intracellular cytokines production and clinical immunology (NI5470)

To elaborate protocol for detection of intracellular cytokines production - choose of acceptable mitogens, cytokines and cellular subsets. To evaluate contribution of this protocol for using in clinical practise - for appreciation of actual status of...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1999 - 2001
    • •
  • 1 780 tis. Kč
    • •
  • 1 780 tis. Kč
    • •
  • MZ
Project

Th1/Th2 cytokine gene polymorphisms in patients with idiopathic pulmonary fibrosis. Correlation with gene expression and cytokine production in bronchoalveolar lavage fluid and with clinical (NR9131)

The goal of our research is the investigation of 50 adult patients with IPF with the diagnosis based on American Thoracic Society/European Respiratory Society (ATS/ERS) statement criteria and 20 children with IPF. We will collect blood samples of the...

EB - Genetika a molekulární biologie

  • 2007 - 2009
    • •
  • 4 622 tis. Kč
    • •
  • 4 539 tis. Kč
    • •
  • MZ
Project

Genetic regulation of cytokine expression-implications for infectious and transplantation immunology (IAA5052604)

, and disease susceptibility, in order to better understand factors which lead to TH1/TH2...

EB - Genetika a molekulární biologie

  • 1996 - 1998
    • •
  • 1 581 tis. Kč
    • •
  • 1 122 tis. Kč
    • •
  • AV ČR
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