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17 (0,151s) •

Project

Structural studies of transcriptional regulators of the DeoR and GntR families involved in catabolic repression in Bacillus subtilis. (ME08016)

specific repressors and activators controlling the level of transcription of catabolic genes. Transcriptional repressors involved in catabolic repression mainly belong structures of the effector binding domains of two transcription...

CE - Biochemie

  • 2008 - 2012
    • •
  • 1 240 tis. Kč
    • •
  • 1 240 tis. Kč
    • •
  • MŠMT
Project

Flavivirus-host interactions on the transcriptional and translational level (LTAUSA18040)

The proposed project is aimed at description of interaction between the tick-borne encephalitis virus and other flaviviruse with host cells on the level of transciption and translation and description of the effects of infection on the cell ...

Genetics and heredity (medical genetics to be 3)

  • 2019 - 2022
    • •
  • 8 734 tis. Kč
    • •
  • 8 734 tis. Kč
    • •
  • MŠMT
Project

Investigating the Symmetric Allosteric Mechanism of Hexameric Escherichia coli Arginine Repressor using Computational Simulations (GA13-21053S)

Allostery is a manifestation of the global response of a macromolecule to ligand binding. The molecular origins of this fascinating emergent phenomenon have been a holy grail of biochemistry ever since Monod and Jacob named the concept. Arginine ...

CF - Fyzikální chemie a teoretická chemie

  • 2013 - 2018
    • •
  • 3 883 tis. Kč
    • •
  • 3 883 tis. Kč
    • •
  • GA ČR
Project

Induction of processes blocking the proliferation of leukemic cells by inhibition of transcription of ribosomal genes. (NR7998)

and chemical and physical repressors of proliferation and inductors of program-med cell...

FD - Onkologie a hematologie

  • 2004 - 2006
    • •
  • 6 976 tis. Kč
    • •
  • 6 186 tis. Kč
    • •
  • MZ
Project

New tools in molecular genetics of cyanobacteria - applications in exploration of the chlorophyll biosynthetic pathway (IAA500200713)

RNA or on TetR repressor or nirA promotor. 3) Demonstrate applicability...

EE - Mikrobiologie, virologie

  • 2007 - 2009
    • •
  • 2 423 tis. Kč
    • •
  • 2 423 tis. Kč
    • •
  • AV ČR
Project

Novel components of the Wnt signaling pathway (GA204/04/0532)

, while in the absence of the Wnt signal, TCFs function as transcriptional repressors...

EB - Genetika a molekulární biologie

  • 2004 - 2006
    • •
  • 2 100 tis. Kč
    • •
  • 2 100 tis. Kč
    • •
  • GA ČR
Project

Molecular mechanisms of the tumor suppressor function of the HIC1 gene (GAP305/12/2347)

The research objective of the project is to define the tumor suppressive function of Hic1, transcription repressor that is frequently inactivated in many types of cancer. The experimental work is based on the manipulation of the Hic1 gene in...

EB - Genetika a molekulární biologie

  • 2012 - 2015
    • •
  • 9 953 tis. Kč
    • •
  • 9 953 tis. Kč
    • •
  • GA ČR
Project

Influence of inhibition of TEL/AML1 expression and function using RNAi and HDACi on leukaemic blast biology (GP301/03/D189)

to AML1 converts transcription activator AML1 into transcriptional repressor and thus...

FD - Onkologie a hematologie

  • 2003 - 2006
    • •
  • 695 tis. Kč
    • •
  • 695 tis. Kč
    • •
  • GA ČR
Project

Tumor suppressors in the Wnt signaling pathway (GA204/07/1567)

of the Wnt pathway. HIC1 encodes a zinc-finger transcriptional repressor; additionally...

EB - Genetika a molekulární biologie

  • 2007 - 2010
    • •
  • 4 433 tis. Kč
    • •
  • 4 433 tis. Kč
    • •
  • GA ČR
Project

Regulation of translation initiation during meiotic maturation of pig oocytes by protein factors associated with mRNA 3'-end (GA524/07/1087)

as a repressor and an activator of cytoplasmic polyadenylation. Its activator function...

ED - Fyziologie

  • 2007 - 2009
    • •
  • 2 335 tis. Kč
    • •
  • 2 335 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 17