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460 (0,097s) •

Project

Development of new generation of vaccines based on recombinant vaccinia virus III. (IZ4409)

Development of sale and efficient experimental recombinant vaccine against varicella-zoster virus (VZV) on the basis of vaccinia virus (strains and MVA). Investigation of VZV DNA immunogenicity.......

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1997 - 1999
    • •
  • 5 376 tis. Kč
    • •
  • 3 658 tis. Kč
    • •
  • MZ
Project

VACCINIA VIRUS INFECTION TYPE OF HOST-CELL DEATH, CHANGES OF ITS METABOLISM AND REDOX POTENTIAL (GA310/05/0477)

, attenuated, and especially replication-defective vaccinia viruses have been intensively effective against poxviruses is increasing. Using vaccinia virus strain WR, we observed program. In order to define the proc...

EE - Mikrobiologie, virologie

  • 2005 - 2007
    • •
  • 2 780 tis. Kč
    • •
  • 2 556 tis. Kč
    • •
  • GA ČR
Project

Factors of virulence of vaccinia virus and their role in induction of cell mediated immunity (GA310/04/0004)

The project is focused on study of several nonessencial genes of vaccinia virus Praha, that have been known or supposed to contribute to virus virulence for multiplication of virus in specific cell types (K1L, C7L)...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2004 - 2006
    • •
  • 4 847 tis. Kč
    • •
  • 3 713 tis. Kč
    • •
  • GA ČR
Project

Development of recombinant vaccinia viruses with cytokine genes for tumor therapy. (IZ4414)

The use of recombinant vaccinia virus(VV)carrying cytokine genes in tumour therapy.Replicating and nonreplicating VV recombinants with cytokine genes will be prepared. Biological propertttttties of recombinants and of recombinant pr...

FD - Onkologie a hematologie

  • 1997 - 1999
    • •
  • 7 226 tis. Kč
    • •
  • 5 265 tis. Kč
    • •
  • MZ
Project

Combined Immunotherapy of Tumours Induced by Human Papillomavirus (NR8004)

The aim of the project is to develop an immunotherapeutic procedure against papilloma virus-associated tumours employing prime/boost strategy. The approach combines heterologous vaccines. They include DNA vaccines, recombinant vaccinia

FD - Onkologie a hematologie

  • 2004 - 2006
    • •
  • 13 021 tis. Kč
    • •
  • 10 895 tis. Kč
    • •
  • MZ
Project

Use of dendritic cells infected by attenuated recombinant vaccinia viruses for eliciting of specific immune response (GA310/99/0543)

Use of dendritic cells infected by attenuated recombinant vaccinia viruses the vaccine based on infection of dendritic cells (DC) by recombinant vaccinia viruses (VV with recombinant VV, with alteration of genes, w...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1999 - 2001
    • •
  • 2 745 tis. Kč
    • •
  • 2 625 tis. Kč
    • •
  • GA ČR
Project

Development of new generation of vaccines based on recombinant vaccinia virus II. (IZ1936)

9F - 9

  • 1994 - 1996
    • •
  • 4 224 tis. Kč
    • •
  • 6 259 tis. Kč
    • •
  • MZ
Project

Vectors for gene therapy targeted on stromal cells of solid tumors (NR9238)

HPV16-E7. Recombinant vaccinia virus vectors will allow expression of the ectodomainInvestigation of an anti-tumor therapeutic DNA vaccine and vectors for gene therapy targeting tumor fibroblasts in mouse model of tumors induced by...

FD - Onkologie a hematologie

  • 2007 - 2009
    • •
  • 9 764 tis. Kč
    • •
  • 9 542 tis. Kč
    • •
  • MZ
Project

How does vaccinia virus induce macrophage apoptosis? Role of nitric oxide and cytokines (GA310/96/0514)

viruses replication in macrophages. Our data show, that IFNy- mediated inhibition of viruses replication in macrophages. Our data show, that IFNy-mediated inhibition of vaccinia virus (VV) growth is due to block i...

EE - Mikrobiologie, virologie

  • 1996 - 1998
    • •
  • 2 428 tis. Kč
    • •
  • 1 990 tis. Kč
    • •
  • GA ČR
Project

Yeast linear plasmids as a model for poxviral transcription (GA21-25504S)

, in the synthesis of non-template leaders and the characterization of individual vaccinia virus...

Microbiology

  • 2021 - 2024
    • •
  • 5 679 tis. Kč
    • •
  • 5 679 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 460