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123 (0,329s) •

Project

Epilepsy genetics To solve unsolvable cases with combined OMICs tools (NU20-04-00279)

be further testing, namely by whole-exome (WES), whole-genome (WGS) and long read for WGS and even for LRS. The focus of the project will be on the advanced data......

Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])

  • 2020 - 2023
    • •
  • 8 984 tis. Kč
    • •
  • 8 984 tis. Kč
    • •
  • MZ
Project

Exploring causes of the neurogenetic disorders with the newest genomic methods (NU22-04-00097)

exome (WES), whole genome sequencing (WGS) and the advanced methods used the detection of DNA repeat expansions that are not commonly detected by NGS. WES and WGS). LRS can detect variants not visible with WES or WGS. Ther...

Genetics and heredity (medical genetics to be 3)

  • 2022 - 2025
    • •
  • 10 731 tis. Kč
    • •
  • 10 731 tis. Kč
    • •
  • MZ
Project

Genetics of adult-onset familial focal segmental glomerulosclerosis (FSGS) – implications for individualized therapy and successful kidney transplantation (NV19-06-00443)

Focal segmental glomerulosclerosis (FSGS) is a clinically and genetically heterogeneous entity that manifests mostly by proteinuria. FSGS is responsible for about 15% of end-stage renal disease (ESRD) cases requiring hemodialysis or renal transplanta...

Human genetics

  • 2019 - 2023
    • •
  • 13 856 tis. Kč
    • •
  • 12 179 tis. Kč
    • •
  • MZ
Project

Integrative analysis of high-throughput genomics and multiparameter flow cytometry to improve diagnosis and monitoring of childhood acute leukemia (NV18-08-00385)

Acute lymphoblastic leukemia (ALL) is the most frequent cancer in children. Its improving outcome depends on accurate diagnosis and minimal residual disease (MRD) monitoring as done by flow cytometry. In proposed project we will develop automatic too...

Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

  • 2018 - 2021
    • •
  • 7 624 tis. Kč
    • •
  • 7 624 tis. Kč
    • •
  • MZ
Project

The application of new methods of genomic analysis in cases of rare genetic based diseases with negative results of genetic and genomic analyses. (NV19-08-00137)

The failure to diagnose the cause of a rare genetic disease occurs in ~50% of the cases and the rate of discovery of novel genes and disease-gene relations appears to be declining. We intend to apply multi-OMIC approaches to identify causal genetic ...

Health-related biotechnology

  • 2019 - 2023
    • •
  • 14 485 tis. Kč
    • •
  • 14 485 tis. Kč
    • •
  • MZ
Project

Calibration of weather generator for sites without or with incomplete meteorological observations (GA205/05/2265)

generator (WG) for sites with non-existent or incomplete historical daily weather series (which are normally used to determine WG parameters). The present WG is designed only some daily variables are observed, the missing ...

DG - Vědy o atmosféře, meteorologie

  • 2005 - 2007
    • •
  • 2 093 tis. Kč
    • •
  • 2 093 tis. Kč
    • •
  • GA ČR
Project

Downscaling the Global Climate Models with use of the Stochastic Weather Generator (LD12029)

weather generators (WGs) for downscaling the Global Climate Model (GCM). Aims: (1) Improvement and validation of the WGs. (2) Comparison of their performance with other downscaling methods involved in COST ES1102. (3) Linking the <...

DG - Vědy o atmosféře, meteorologie

  • 2012 - 2015
    • •
  • 781 tis. Kč
    • •
  • 781 tis. Kč
    • •
  • MŠMT
Project

Study of meningococcal population by the whole genome sequencing method - base for update of vaccination strategy (NV19-09-00319)

The project is focused on the study of meningococcal populations by the whole genome sequencing (WGS) method. The WGS method enables a more accurate sequencing methods and allows the study of virulence factors of this agent. WGS...

Infectious Diseases

  • 2019 - 2022
    • •
  • 7 826 tis. Kč
    • •
  • 7 230 tis. Kč
    • •
  • MZ
Project

Genomic epidemiology of invasive diseases caused by Streptococcus pyogenes in the Czech Republic (NW25-09-00190)

diseases in the Czech Republic (CR) using the Whole Genome Sequencing (WGS) method. Analysis of the WGS data will allow detection of S. pyogenes virulence factor genes the expression of known virulence factors. Analysed WGS

Microbiology

  • 2025 - 2028
    • •
  • 9 149 tis. Kč
    • •
  • 8 393 tis. Kč
    • •
  • MZ
Project

Euratex - Innovation and environmental systems in textile industry (1P04LA217)

textile industry, EURATEX, TEXTRANET - association of textile research institutions, environmental systems, integrated product policy, integrated protection against dirtiing......

JP - Průmyslové procesy a zpracování

  • 2004 - 2007
    • •
  • 3 200 tis. Kč
    • •
  • 2 660 tis. Kč
    • •
  • MŠMT
  • 1 - 10 out of 123