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3 882 (0,251s) •

Project

Study of meningococcal population by the whole genome sequencing method - base for update of vaccination strategy (NV19-09-00319)

The project is focused on the study of meningococcal populations by the whole genome sequencing (WGS) method. The WGS method enables a more accurate sequencing methods and allows the study of viru...

Infectious Diseases

  • 2019 - 2022
    • •
  • 7 826 tis. Kč
    • •
  • 7 230 tis. Kč
    • •
  • MZ
Project

Epilepsy genetics To solve unsolvable cases with combined OMICs tools (NU20-04-00279)

be further testing, namely by whole-exome (WES), whole-genome (WGS) and long read sequencing (LRS). We plan to examine about 200 of already selected patients implemented a massively parallel sequencin...

Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])

  • 2020 - 2023
    • •
  • 8 984 tis. Kč
    • •
  • 8 984 tis. Kč
    • •
  • MZ
Project

Analysis of Czech Genomes for Theranostics (EF16_026/0008448)

The project aims to establish national reference genomic database – a resource that will map the genetic variability of Czech population. On the sample of 1000 healthy individuals whole-genome sequencing will be pe...

Genetics and heredity (medical genetics to be 3)

  • 2019 - 2023
    • •
  • 73 378 tis. Kč
    • •
  • 73 378 tis. Kč
    • •
  • MŠMT
Project

Unleashing the Potential of Whole-Genome Sequencing for Routine Clinical Microbiology and Epidemiology (NW24-09-00126)

techniques like whole-genome sequencing (WGS). WGS enables the characterization treatment strategies. By analyzing complete genome sequences, important features and transmission dynamics...

Microbiology

  • 2024 - 2027
    • •
  • 9 875 tis. Kč
    • •
  • 9 875 tis. Kč
    • •
  • MZ
Project

Exploring causes of the neurogenetic disorders with the newest genomic methods (NU22-04-00097)

of different, new genomic methods to help elucidate the cause of their disorder. The whole exome (WES), whole genome sequencing (WGS) and the advanced methods usedThe diagnostic yield of next gen...

Genetics and heredity (medical genetics to be 3)

  • 2022 - 2025
    • •
  • 10 731 tis. Kč
    • •
  • 10 731 tis. Kč
    • •
  • MZ
Project

Genome of Europe (9H24001)

The aim of the Genome of Europe (GoE) project is to create a reference genomic database with 100,000 sequenced genomes that will be representative of the European population. As part of the project, the Czech Repub...

Human genetics

  • 2024 - 2028
    • •
  • 32 379 tis. Kč
    • •
  • 17 956 tis. Kč
    • •
  • MŠMT
Project

Genomics of replicated cichlid diversification in rivers The role of hybridization in adaptive radiation of Neotropical pike cichlids (Crenicichla) (GA19-20012S)

diversification and representing distinct trophic roles will be used. Based on whole genome sequencing of 250 individuals we will analyze introgressive gene flow to distinguish will sequence and assemble a referen...

Zoology

  • 2019 - 2022
    • •
  • 7 832 tis. Kč
    • •
  • 7 832 tis. Kč
    • •
  • GA ČR
Project

Analysis of the genetic etiology of progressive hearing loss using WGS and innovative bioinformatics approaches (NW24J-06-00119)

by whole genome sequencing (WGS) and innovative bioinformatic approaches. We will use WGS to investigate 40-60 patients with clearly genetic cause of HL (familial cases the study we also found that not a...

Human genetics

  • 2024 - 2027
    • •
  • 6 961 tis. Kč
    • •
  • 6 961 tis. Kč
    • •
  • MZ
Project

Genomic epidemiology of invasive diseases caused by Streptococcus pyogenes in the Czech Republic (NW25-09-00190)

diseases in the Czech Republic (CR) using the Whole Genome Sequencing (WGS) method. Analysis of the WGS data will allow detection of S. pyogenes virulence factor genes the expression of known virulence fa...

Microbiology

  • 2025 - 2028
    • •
  • 9 149 tis. Kč
    • •
  • 8 393 tis. Kč
    • •
  • MZ
Project

Antibiotic resistance routes of dissemination, means of evolution and adaptation Incorporating WGS in the equation (NU20J-05-00033)

and its comparison with the carbapenem-susceptible population will be performed. Whole genome sequencing and bioinformatics analysis will allow to identify specific-threatening infections. In this project, molecular-epidem...

Microbiology

  • 2020 - 2023
    • •
  • 9 370 tis. Kč
    • •
  • 9 370 tis. Kč
    • •
  • MZ
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