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Projects

11 483 projects (0,126s)

Project

Biodegradable depot system for targeted transdermal delivery of biologically active substances (EG16_084/0010272)

Biodegradable depot system for targeted transdermal delivery of biologically active substances...

FO - Dermatovenerologie

  • 2017 - 2020
  • 13 533 tis. Kč
  • 2 842 tis. Kč
  • MPO
Project

Profiling and targeting of employment services (HC196/10)

The project aims to increase the efficiency of workers of employment services and better targeting tools of active employment policy. Statistical profiling and targeting can contribute to better targeting tools and...

AH - Ekonomie

  • 2010 - 2010
  • 1 810 tis. Kč
  • 1 810 tis. Kč
  • MPSV
Project

Polymer conjugates of drugs targeted with specific oligopeptides (GA204/05/2255)

systémrepresents a unique system enabling duál drug targeting and dual therapeutic activity of the polymer drug. Dual targeting will be achieved by combination of an active targeting and biological proper...

CD - Makromolekulární chemie

  • 2005 - 2007
  • 5 421 tis. Kč
  • 5 421 tis. Kč
  • GA ČR
Project

Intracellular and extracellular targets for antitumor activity and toxicity of ruthenium complexex (1P05OC070)

complexex of rhutenium as a new class of promising cytostatics effective in tumor cell resistant to platinum cytostatics...

FR - Farmakologie a lékárnická chemie

  • 2005 - 2006
  • 705 tis. Kč
  • 522 tis. Kč
  • MŠMT
Project

Peptide Drug Delivery Systems Targeting Macrophages for Antimycobacterial Active Compounds (GJ17-27514Y)

The project is focused on the development of novel macrophage-targeting drug via various linkers. Oligotuftsin carriers that target specifically macrophages will be functionalized by mannose derivatives with the aim to increase the ...

FR - Farmakologie a lékárnická chemie

  • 2017 - 2019
  • 4 525 tis. Kč
  • 4 525 tis. Kč
  • GA ČR
Project

Targeted polymer theranostics for advanced site-specific inflammation treatment (GJ19-00956Y)

as a versatile system allowing passive and active drug targeting into the inflammation site and active targeting in inflammation treatment. biodegradable spacers enabling their controlled activation mainl...

Polymer science

  • 2019 - 2022
  • 5 451 tis. Kč
  • 4 830 tis. Kč
  • GA ČR
Project

Development of method for membrane protein target identification of biologically active small molecules (GA23-05642S)

. For further development of these hits, it is necessary to identify their target protein to attach multiple molecules of the active compound to a hydrophilic copolymer bearing of the target protein. This will facilitate st...

Polymer science

  • 2023 - 2025
  • 8 931 tis. Kč
  • 8 706 tis. Kč
  • GA ČR
Project

Ferritin as a tool for enzymes-directed prodrug activation (NU21J-08-00043)

Targeted therapy, delivering biologically active substances to tumors without some therapeutics benefiting from targeted therapy have been employed in anticancer aims to establish a novel concept of smart therapy, based on ...

Nano-materials (production and properties)

  • 2021 - 2024
  • 6 120 tis. Kč
  • 6 120 tis. Kč
  • MZ
Project

Phage-based targeted neural stimulation in neurodegenerative diseases (8F21004)

Engineering and functionalization of NPhs constructs, Assessment of in vitro biocompatibility, BBB crossing and targeting efficacy of NPhs constructs, Selective in vitro neuronal activation by NPhs,......

Other medical science

  • 2021 - 2024
  • 6 571 tis. Kč
  • 6 571 tis. Kč
  • MŠMT
Project

Mechanisms of Target Cell Recognition with Cytotoxic Cells and their Relationship to the Mode of Activation (IA52052)

9G - 9

  • 1992 - 1994
  • 0 tis. Kč
  • 0 tis. Kč
  • AV ČR
  • 1 - 10 out of 11 483