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16 (0,078s) •

Project

Mechanisms of Salt-Induced Hypertension in Primary Aldosteronism (LUAUS23095)

-dependent form of HTN caused by aldosterone excess. The most common secondary form of HTN is primary aldosteronism (PA) when recent studies indicated that its is the hemodynamic abnormality through which aldosterone enable...

Cardiac and Cardiovascular systems

  • 2023 - 2027
    • •
  • 3 362 tis. Kč
    • •
  • 3 362 tis. Kč
    • •
  • MŠMT
Project

Development of immunoassay RIA kits based on steroid histamine derivatives (FV20061)

for determination of free testosterone, progesterone, aldosterone and cortisol. The main aim of free testosterone per labeling by radioactive iodine 125I 3. (2019). - Aldosterone on and will be a part of confidential information su...

CE - Biochemie

  • 2017 - 2020
    • •
  • 12 874 tis. Kč
    • •
  • 7 359 tis. Kč
    • •
  • MPO
Project

Contribution of the RAAS to the pathophysiology of salt-sensitive hypertension a study in renin transgenic rats with inducible hypertension (GP305/08/P053)

Recent studies have implicated an important role of the renin-angiotensin-aldosterone system (RAAS) in the development of salt-sensitive hypertension. This study angiotensinII (ANG II) and aldosterone levels as the consequence of en...

ED - Fyziologie

  • 2008 - 2010
    • •
  • 1 485 tis. Kč
    • •
  • 1 485 tis. Kč
    • •
  • GA ČR
Project

Polymorphisms of selected candidate genes in different stages of essential hypertension. (NA7171)

Three polymorphisms of genes, responsible for synthesis and organ effects of aldosterone and catecholamines and their association with clinical manifestation, progression, organ complications and effectiveness of therapy will be studied in E...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2002 - 2004
    • •
  • 2 182 tis. Kč
    • •
  • 2 116 tis. Kč
    • •
  • MZ
Project

The frequency and diagnosis of primary aldosteronism in the population of Czech Republic. (IZ2314)

9F - 9

  • 1994 - 1996
    • •
  • 114 tis. Kč
    • •
  • 174 tis. Kč
    • •
  • MZ
Project

Effect of the specific treatment of primary aldosteronism on subclinical organ damage regression (NT14155)

aldosteronism (PA) 5 years after adrenalectomy or after start of specific treatment...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2013 - 2015
    • •
  • 2 756 tis. Kč
    • •
  • 2 756 tis. Kč
    • •
  • MZ
Project

European Project on Genes in Hypertension (EPOGH) (OK 375)

on the system renin - angiotensin - aldosterone....

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 1999 - 2002
    • •
  • 1 197 tis. Kč
    • •
  • 1 157 tis. Kč
    • •
  • MŠMT
Project

The role of impaired renal autoregulation and the tissue renin-angiotensin-aldosterone system in the pathophysiology of chronic renal failure (GC305/08/J006)

Hypertension and the renin-angiotensin-aldosterone system (RAAS) play a major role in the progression of chronic kidney disease (CKD). It has been claimed that blockade of RAAS provides renoprotective effects in attenuating the progression o...

ED - Fyziologie

  • 2008 - 2010
    • •
  • 2 940 tis. Kč
    • •
  • 2 940 tis. Kč
    • •
  • GA ČR
Project

Comparison of the morphological and functional changes of the arterial wall in patients with different types of arterial hypertension (NR8155)

of the arterial wall in patients with primary aldosteronism (PA) and in patients with esential...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2004 - 2008
    • •
  • 1 934 tis. Kč
    • •
  • 1 346 tis. Kč
    • •
  • MZ
Project

The mechanisms of interaction between renin-angiotensin-aldosterone system, cytochrome P450 metabolites and other vasoactive systems in the regulation of blood pressure and the impact (LH11116)

The main objective of our projects is to identify the functional interactions between RAAS and CYP450 effect that are involved in the regulation of blood pressure and its impact on pathophysiology of salt-sensitive and angiotensin II-dependent hypert...

ED - Fyziologie

  • 2011 - 2013
    • •
  • 1 120 tis. Kč
    • •
  • 1 120 tis. Kč
    • •
  • MŠMT
  • 1 - 10 out of 16