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430 (0,089s) •

Project

Identification of novel molecular pathways involved in the process of B-cell allelic exclusion; chronic lymphocytic leukemia as the model system (NS9652)

Allelic exclusion is a unique phenomenon, ensuring antibody monospecificity exclusion.By microarray RNA expression profiling of clonal CLL cells with allelic exclusion to identify genes that might play a role in th...

FD - Onkologie a hematologie

  • 2008 - 2011
    • •
  • 8 112 tis. Kč
    • •
  • 8 082 tis. Kč
    • •
  • MZ
Project

Young kids or old migrants? Colonization versus in situ speciation of allopolyploid apomicts in European alpine sky islands (GA22-16651S)

to resolve these issues. We expect that the geographical distribution of alleles and a pattern of allele sharing / exclusivity among parental ancestors and their apomictic-exclusive hypotheses will be tested in tw...

Plant sciences, botany

  • 2022 - 2024
    • •
  • 10 112 tis. Kč
    • •
  • 10 112 tis. Kč
    • •
  • GA ČR
Project

Analysis of haplotypes in wild and wild-derived mice on chromosome 17 (IAA5052406)

for alleles/genotypes and their combinations on a single chromosome of a given individual. domesticus and M. m. musculus to estimate the number of alleles. In pilot experiments, the haplotype structure of wild-derived strains will ...

EB - Genetika a molekulární biologie

  • 2004 - 2008
    • •
  • 3 396 tis. Kč
    • •
  • 2 146 tis. Kč
    • •
  • AV ČR
Project

Detection and characterization of "blank" HLA class 1 alleles in the Czech population. Implications for transplant medicine (NM6522)

Examination of "blank" HLA class I alleles - using DNA sequencing and flow cytometry to determine their frequency and to analyze HLA molecule expression on cell surface - in the healthy Czech population and in patients awaiting organ transpl...

EB - Genetika a molekulární biologie

  • 2001 - 2003
    • •
  • 2 749 tis. Kč
    • •
  • 2 583 tis. Kč
    • •
  • MZ
Project

Immunogenetics of lung inflammation VNTR polymorphims of IL-1RA (IL-1 receptor antagonist) gene and pulmonary fibrosis (idiopathic, secondary) (GA310/99/1676)

is to investigate if allele 2 of IL-1RA gene determines an "immunological phenotype" leadingto associated with rheumatological disease we wish to investigate if allele 2 affects to study if allele 2 is a susceptibility fac...

EC - Imunologie

  • 1999 - 2001
    • •
  • 597 tis. Kč
    • •
  • 597 tis. Kč
    • •
  • GA ČR
Project

Social Exclusion of Seniors 65+ Living in a Home Surrounding in the Czech Republic (LTC18066)

of the social exclusion of seniors in the Czech Republic aged 65+ and liviving at home. The causes, forms and consequences of social exclusion will be determined according to selected types of social exclusion. Sub-objecti...

Sociology

  • 2018 - 2020
    • •
  • 3 694 tis. Kč
    • •
  • 3 694 tis. Kč
    • •
  • MŠMT
Project

Function study of allelic variants of urate transporters in primary hyperuricemia and gout (NV15-26693A)

The aim of our study is to clarify the frequency, the role and the function effect of selected allelic variants of urate transportosome to the serum uric acid normouricemia controls). Selected allelic variants (genotyping of ten gen...

FP - Ostatní lékařské obory

  • 2015 - 2019
    • •
  • 9 818 tis. Kč
    • •
  • 9 818 tis. Kč
    • •
  • MZ
Project

Social Exclusion and Social Inclusion in the Czech Society (GA403/03/1007)

The concept of social exclusion is usually defined as an exclusion from wages with job insecurity. It can also consist in exclusion based on ethnicity or on othergrounds. This is linked to exclusion from the standa...

AO - Sociologie, demografie

  • 2003 - 2005
    • •
  • 2 511 tis. Kč
    • •
  • 2 511 tis. Kč
    • •
  • GA ČR
Project

A variety of TP53 aberrant states in the clinical and biological behavior of chronic lymphocytic leukemia cells. (NW24-03-00114)

The functional heterogeneity of TP53 defects, consisting of the type of individual allele´s defect, aberration proportion, and genetic background, hampers but are more common in CLL. We will explore whether the second allele is trul...

Oncology

  • 2024 - 2027
    • •
  • 16 112 tis. Kč
    • •
  • 16 112 tis. Kč
    • •
  • MZ
Project

Characterization of novel high-molecular-weight glutenin subunits in synthetic wheats and resistance to leaf diseases (MEB0810001)

Characterisation of potentially new HMW glutenin subunits detected in population of synthetic wheat using electrophoresis. The wheat (Triticum aestivum L.) lines with unknown alleles for the storage proteins will be multiply and also if pote...

EB - Genetika a molekulární biologie

  • 2010 - 2011
    • •
  • 106 tis. Kč
    • •
  • 106 tis. Kč
    • •
  • MŠMT
  • 1 - 10 out of 430