All
All

What are you looking for?

All
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”
EN
ČeštinaEnglish

Filters

-
19852030

Join usingOrAnd

Join usingOrAnd

SelectAll/None

      • Show more

      • Show more

      • Show more

      • Show more

    • Show more

SelectAll/None

Join usingOrAnd

-

More filters

Projects

248 projects (0,11s) •

Project

New strategy for inhibition of amyloid fibril formation (GJ18-06255Y)

Misfolding of the protein alpha-synuclein is the key step in the development autocatalytic prion-like process. Currently available methods for preventing alpha-synuclein that either bind and stabilize native form o...

Biophysics

  • 2018 - 2021
    • •
  • 5 695 tis. Kč
    • •
  • 5 695 tis. Kč
    • •
  • GA ČR
Project

Interfacial properties of alpha-synuclein and aggregation of this protein in Parkinson's disease (KJB100040901)

Parkinson's disease is the second most common neurodegenerative disease that affects coordination of movement in sufferers, associated with the formation and deposition of amyloid fibrils of the protein alpha-synuclein (AS). Studies...

BO - Biofyzika

  • 2009 - 2011
    • •
  • 1 620 tis. Kč
    • •
  • 1 620 tis. Kč
    • •
  • AV ČR
Project

3-Nitro-L-tyrosine in structures of neurodegenerative proteins (GA14-00431S)

and alpha-synuclein models. The first one plays role in transmissible spongiform...

CF - Fyzikální chemie a teoretická chemie

  • 2014 - 2016
    • •
  • 4 344 tis. Kč
    • •
  • 4 344 tis. Kč
    • •
  • GA ČR
Project

TACKLing the challenges of PREsymptomatic sporadic Dementia (8F2205)

To leverage large, multimodal datasets from patients representing the full spectrum of neurodegenerative dementia as well as those at risk and apply well-informed data-driven analytic approaches to identify neurodegenerative dementia spectra and bio...

Neurosciences (including psychophysiology)

  • 2022 - 2024
    • •
  • 9 786 tis. Kč
    • •
  • 9 786 tis. Kč
    • •
  • MŠMT
Project

TACKLing the challenges of PREsymptomatic sporadic Dementia (8F22005)

To leverage large, multimodal datasets from patients representing the full spectrum of neurodegenerative dementia as well as those at risk and apply well-informed data-driven analytic approaches to identify neurodegenerative dementia spectra and biot...

Neurosciences (including psychophysiology)

  • 2022 - 2025
    • •
  • 9 786 tis. Kč
    • •
  • 9 786 tis. Kč
    • •
  • MŠMT
Project

Utilization of RT-QuIC assay for improvement of diagnostics of neurodegenerative diseases Prospective and retrospective studies (NU23-04-00173)

for misfolded alpha-synuclein and finished its pilot validation using archive brain and CSF...

Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

  • 2023 - 2026
    • •
  • 13 085 tis. Kč
    • •
  • 13 085 tis. Kč
    • •
  • MZ
Project

Membrane interactions of proteins associated with alzheimer's disease and parkinson's disease implications for diseases' pathologies and therapeutic avenues (LH13259)

Aberrant misfolding and aggregation of amyloidogenic proteins is implicated in the progression of neurodegenerative diseases, including Alzheimer?s disease, Parkinson?s disease, and others. While the exact molecular factors responsible for the occurr...

BO - Biofyzika

  • 2013 - 2015
    • •
  • 1 365 tis. Kč
    • •
  • 1 365 tis. Kč
    • •
  • MŠMT
Project

Influence of tyrosine oxidation on structure of neurodegenerative proteins (GA17-00121S)

will be the prion protein and alpha-synuclein models. The first one plays role in transmissible...

BO - Biofyzika

  • 2017 - 2021
    • •
  • 5 864 tis. Kč
    • •
  • 5 669 tis. Kč
    • •
  • GA ČR
Project

Spatiotemporal transcriptome and proteome analysis of α-Synuclein pathology in Parkinson’s disease Identification of cell type-specific vulnerability and tolerance mechanisms (9F24003)

1. Spatiotemporal analysis of neuronal, glial and immune cell responses at transcriptome and proteome level in vulnerable and more resistant brain regions; 2. Multi-omic bioinformatics analysis of spatiotemporal gene and protein expression changes, s...

Other medical science

  • 2024 - 2027
    • •
  • 6 633 tis. Kč
    • •
  • 6 633 tis. Kč
    • •
  • MŠMT
Project

Metrology for emerging targeted alpha therapies (9B23008)

The overall objective of the project is to address the unique and unmet metrological challenges of targeted alpha therapies....

Nuclear physics

  • 2023 - 2026
    • •
  • 11 873 tis. Kč
    • •
  • 5 937 tis. Kč
    • •
  • MŠMT
  • 1 - 10 out of 248