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526 (0,239s) •

Project

Self-assembly of amphiphilic peptides with helical character (GA14-12598S)

conditions and properties of self-assembly of amphiphilic peptides with prolate shapeIn living organisms, a wide variety of peptides self-assemble into a range and, at the same time, contain the essential features of under...

CF - Fyzikální chemie a teoretická chemie

  • 2014 - 2018
    • •
  • 4 460 tis. Kč
    • •
  • 4 460 tis. Kč
    • •
  • GA ČR
Project

Amphiphilic Peptides at Phospholipid Membranes (GA17-11571S)

barrier function, which can be altered by interaction with amphiphilic peptides. In particular, antimicrobial and cell-penetrating peptides are of high importance due by these peptides. Using computer simulations ...

CF - Fyzikální chemie a teoretická chemie

  • 2017 - 2021
    • •
  • 4 803 tis. Kč
    • •
  • 4 803 tis. Kč
    • •
  • GA ČR
Project

Peptide Killers of Bacteria (LL2007)

We will develop a method for the targeting of peptides to membranes with specific lipid composition and determine key peptide properties for membrane translocation and pore formation. The designed peptides will be experimen...

Atomic, molecular and chemical physics (physics of atoms and molecules including collision, interaction with radiation, magnetic resonances, Mössbauer effect)

  • 2020 - 2021
    • •
  • 13 476 tis. Kč
    • •
  • 13 476 tis. Kč
    • •
  • MŠMT
Project

Supramolecular Structures of Amphiphilic Block Copolymers Containing Oligopeptide Segments (KJB4050311)

Hydrogel-like biodegradable copolymers featuring practical applications can be prepared combining poly(ethylene oxide) hydrophilic chains with hydrophobic oligopeptide segments (OS's containing several charged (either positively or negatively) sidech...

CD - Makromolekulární chemie

  • 2003 - 2005
    • •
  • 2 364 tis. Kč
    • •
  • 1 884 tis. Kč
    • •
  • AV ČR
Project

Protein Affinity and Selectivity to Cellular Membranes (GA20-20152S)

membranes. The membranes to which we will design new peptides include human plasma on amphiphilic helices, a frequent membrane binding motif, and few selected complex proteins......

Physical chemistry

  • 2020 - 2022
    • •
  • 8 105 tis. Kč
    • •
  • 8 105 tis. Kč
    • •
  • GA ČR
Project

Theoretical and Experimental Study of Dynamic Micelles of Amphiphilic Gradient Copolymers (MEB020911)

(i) Synthesis and characterization of amphiphilic gradient copolymers. (ii) Experimental study of their conformational behavior and self-assembly by scattering, spectroscopy (NMR and fluorescence) and microscopy (TEM, AFM) techniques. (iii) ...

CD - Makromolekulární chemie

  • 2009 - 2010
    • •
  • 106 tis. Kč
    • •
  • 106 tis. Kč
    • •
  • MŠMT
Project

Preparation of surface nanoclusters of integrin ligands for control of cell adhesion (GPP207/10/P569)

of peptide-derived integrin ligands using spherical nanoparticles assembled from amphiphilic diblock copolymers. Ligands will be conjugated on the nanoparticles to create......

CD - Makromolekulární chemie

  • 2010 - 2014
    • •
  • 1 008 tis. Kč
    • •
  • 1 008 tis. Kč
    • •
  • GA ČR
Project

Self-assembled structures of amphiphilic gradient copolymers for conceptually new applications (GA19-01602S)

The curiosity-driven aim of the project is to gain knowledge about the internal structure, physico-chemical and biological behavior of gradient amphiphilic copolymers is to use this knowledge to construct new paradigm next generation amp...

Polymer science

  • 2019 - 2021
    • •
  • 7 300 tis. Kč
    • •
  • 7 207 tis. Kč
    • •
  • GA ČR
Project

Synthesis of novel amphiphilic gels for biomedical use and study of their properties (GA203/04/1050)

The project is focused on the preparation of novel types of amphiphilic gels for biomedical use. Polyisobutylene forms the hydrophobic part of these gels, and poly(hydroxyalkyl methacrylate)s, polyacrylamides or polyglycols form their hydrop...

CD - Makromolekulární chemie

  • 2004 - 2006
    • •
  • 2 140 tis. Kč
    • •
  • 2 140 tis. Kč
    • •
  • GA ČR
Project

Chaotrope, hydrotrope or surfactant? Anionic boron cluster compounds in water and in complexes with polymers (GA17-00648S)

The aim of the proposed project is an experimental study of anionic boron cluster compounds as only partly explored class of amphiphilic compounds. Structure the structure of classical amphiphiles and surfactants (hydrophobic tail a...

CD - Makromolekulární chemie

  • 2017 - 2019
    • •
  • 4 285 tis. Kč
    • •
  • 4 182 tis. Kč
    • •
  • GA ČR
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