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52 (0,173s) •

Project

Inhibitors of angiogenesis in multiple myeloma (NR8076)

Aim of the project is evaluation of the concentrations of angiogenesis inhibitors in patiens with multiple myeloma importance. Concentration of angiogenesis inhibitors in plasma and bone marrow plasma will be verified by ELISA. ...

FD - Onkologie a hematologie

  • 2004 - 2006
    • •
  • 1 640 tis. Kč
    • •
  • 1 629 tis. Kč
    • •
  • MZ
Project

Relation of angiogenesis to ZAP-70 expression and clinical course in chronic kymphocytic leukemia (NR8373)

At the time of diagnosis of CLL, ZAP-70 expression will be measured by ELISA technique and angiogenesis will be assessed using immunohistochemical examination of bone marrow trephine biopsies and determination of plasma levels of angiogenic ...

FD - Onkologie a hematologie

  • 2005 - 2007
    • •
  • 693 tis. Kč
    • •
  • 685 tis. Kč
    • •
  • MZ
Project

Photocontrol of RNA Activity with Red Light Using Cyclic Tethers (GF25-19862L)

Angiogenesis, the formation of new blood vessels, is a critical process upregulation of angiogenesis poses significant risks, underscoring the need for spatial 34a and 92a, key regulators of angiogenesis, in cell cultures. ...

Biochemistry and molecular biology

  • 2025 - 2028
    • •
  • 5 803 tis. Kč
    • •
  • 5 803 tis. Kč
    • •
  • GA ČR
Project

Inhibition of angiogenesis as as an efficient way to suppress pancreatic cancer (NT14078)

cancer are required. Such a process is angiogenesis. In the course of this project will follow the effect of new vitamin E analogues on angiogenesis derived from pre......

FD - Onkologie a hematologie

  • 2013 - 2015
    • •
  • 7 075 tis. Kč
    • •
  • 7 075 tis. Kč
    • •
  • MZ
Project

Angiogenesis, angiogenic cytokines and indices of plasma cell kinetics in multiple myeloma clinical and prognostic significance (NC7503)

Assessment of the relation of the angiogenesis density to the parametrs of kinetics of myeloma cells ( propidium iodide index/CD138 and markers of apoptosis -annexin V-FITC, PARP, caspase 3 and 8, p53 and Bcl-2) and cyclin D1. Comparison). C...

FD - Onkologie a hematologie

  • 2003 - 2005
    • •
  • 2 338 tis. Kč
    • •
  • 2 305 tis. Kč
    • •
  • MZ
Project

Predictive and prognostic factors in breast cancer patients treated with neoadjuvant chemotherapy (NR8392)

The aim of the project is to evaluate predictive significance of biological factors, including tumor phenotype, parameters of angiogenesis or immune response, in breast cancer patients treated by neoadjuvant chemotherapy. Immunohistochemical...

FD - Onkologie a hematologie

  • 2005 - 2007
    • •
  • 7 463 tis. Kč
    • •
  • 7 189 tis. Kč
    • •
  • MZ
Project

Study of angiogenesis and remodelling of human placenta capillary network using confocal and two-photon microscopy, stereology and 3-D image analysis (GA304/05/0153)

The main goal of the project is to study angiogenesis and vascular remodelling of capillary segments of human placental terminal villi. Angiogenesis in the course of capillary segments will be revealed by visualization of angiogenic...

EA - Morfologické obory a cytologie

  • 2005 - 2007
    • •
  • 2 227 tis. Kč
    • •
  • 2 227 tis. Kč
    • •
  • GA ČR
Project

Role of angiogenesis in mantle cell lymphoma (MCL) survival, growth, spread and response to therapy (NT13201)

Mantle cell lymphoma (MCL) is incurable B-cell non-Hodgkin lymphoma. Preclinical testing of experimental treatment strategies is requisite for design of future clinical trials. Antiangiogenic molecules appear to be uniquely active in MCL, including t...

FD - Onkologie a hematologie

  • 2012 - 2015
    • •
  • 9 892 tis. Kč
    • •
  • 9 892 tis. Kč
    • •
  • MZ
Project

Mono- and multivalent inhibitors of galectin-8 in tumour-associated (lymph)angiogenesis (GF25-16301K)

and in newly developed (lymph)angiogenesis assays with Gal-8-expressing cell lines...

Medicinal chemistry

  • 2025 - 2028
    • •
  • 6 480 tis. Kč
    • •
  • 6 480 tis. Kč
    • •
  • GA ČR
Project

Laboratory of molecular pathophysiology and molecular morphology (VS97108)

The laboratory will combine the functional and morphological approach to studies of molecular mechanisms of developmental, adaptive and reparative processes. The expression of genes for growth factors and receptors of angiogenesis and haemat...

EB - Genetika a molekulární biologie

  • 1997 - 2000
    • •
  • 35 228 tis. Kč
    • •
  • 22 778 tis. Kč
    • •
  • MŠMT
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