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10 760 (0,112s) •

Project

Production of Dendrobium candidum biomass in vitro and study its biological activity (LH12164)

The project aims are: a) production of Dendrobium candidum biomass by callus and cell cultures b) assess anti-inflammatory (cyclooxygenase-1 and -2 and 5-lipoxygense inhibition) and anti-oxidative activity (by DPPH...

EI - Biotechnologie a bionika

  • 2012 - 2013
    • •
  • 1 440 tis. Kč
    • •
  • 1 440 tis. Kč
    • •
  • MŠMT
Project

Pre-Clinical Testing of Anti-Oxidative Effects Original Substances on Defined Pathological Conditions (NL5881)

Pre-clinical testing of anti-oxidative effects of substances under artificially induced pathological conditions of diabetes mellitus and ischaemia-reperfusion of kidney tissue. The tested substances will include natural and syntheti...

FR - Farmakologie a lékárnická chemie

  • 2000 - 2002
    • •
  • 2 613 tis. Kč
    • •
  • 2 613 tis. Kč
    • •
  • MZ
Project

Resveratrol as biological active compound and its significance for human health (GA525/99/1338)

as so called French paradox and anti-cancer chemo-preventive activity. The denominator of those activities are anti-oxidizing features of resveratrol molecule of resveratrol in regard to its further use a...

GM - Potravinářství

  • 1999 - 2001
    • •
  • 1 353 tis. Kč
    • •
  • 1 194 tis. Kč
    • •
  • GA ČR
Project

Establishing the signaling pathway associated with secondary injury, reactive oxygen species and inflammation in spinal cord injury and during its repair. (LTAUSA17120)

To study signalling pathways activated during spinal cord injury, particularly mTOR pathway in cells and in spinal cord tissue. To study inhibition of mTOR pathway using blocators of mTORC1 or mTORC2 complex. To study the effect of anti<...

FH - Neurologie, neurochirurgie, neurovědy

  • 2017 - 2020
    • •
  • 7 673 tis. Kč
    • •
  • 7 673 tis. Kč
    • •
  • MŠMT
Project

New methods for the improvement of diagnostic as well as therapeutic purposes of the human eye with dry eye syndrome (NR8828)

The dry eye syndrome may be associated with increased amount of oxyradicals and destructive proteases at the ocular surface. Active urokinase is not present in the tear fluid of the normal human eye. The finding of active urokinase ...

FF - ORL, oftalmologie, stomatologie

  • 2006 - 2008
    • •
  • 2 880 tis. Kč
    • •
  • 2 812 tis. Kč
    • •
  • MZ
Project

Perinatal development of human anti- oxidative enzyme system and his dysfunctions. (IZ999)

9G - 9

  • 1992 - 1994
    • •
  • 0 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • MZ
Project

Metabolic effect of L-arginine supplementation and ACE inhibitors in diabetes and renal insuficience. (IZ4201)

The effect of long-term administration of L-arginine, the substrate for nitric oxide synthesis, and ACE inhibitors on metabolic disorders, the function and anti-oxidative capacity of the heart will be investigated.......

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1997 - 1999
    • •
  • 2 122 tis. Kč
    • •
  • 1 539 tis. Kč
    • •
  • MZ
Project

Melanoidins in food and healts (OC 919.10)

with metals and oxygen (anti-, pro-oxidative activity), influence on oxidative stabilityThe aim of this research is to gain knowledge on melanoidins, some other Maillard reaction products and their influence on ar...

GM - Potravinářství

  • 1999 - 2004
    • •
  • 4 443 tis. Kč
    • •
  • 3 818 tis. Kč
    • •
  • MŠMT
Project

Stress hormones and their potential usage in insect pest control (GAP501/10/1215)

) Study of AKH role in mobilization of anti-oxidative stress reactions in suitable of AKH in the control of activity of digestive enzymes or their inhibitors, and study......

GF - Choroby, škůdci, plevely a ochrana rostlin

  • 2010 - 2013
    • •
  • 3 966 tis. Kč
    • •
  • 3 966 tis. Kč
    • •
  • GA ČR
Project

Novel Tools for Cell Cycle Analysis (TA03010719)

The determination of the cell proliferation activity is a basic methodological approach for the evaluation of the cell population conditions in many situations e.g. in the evaluation of the genotoxicity or in the analysis of the effect of ag...

EI - Biotechnologie a bionika

  • 2013 - 2015
    • •
  • 9 600 tis. Kč
    • •
  • 6 000 tis. Kč
    • •
  • TA ČR
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