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682 (0,173s) •

Project

Polymer terapeutics based on antimicrobial peptides for multi-resistence bakteria species treatment (GA20-04790S)

and biological properties of novel biodegradable star polymer-antimicrobial peptide constructs tailor-made for targeted delivery and activation of antimicrobial peptides containing peptides bound via spac...

Polymer science

  • 2020 - 2022
    • •
  • 5 461 tis. Kč
    • •
  • 5 461 tis. Kč
    • •
  • GA ČR
Project

Antimicrobial peptides from insects for possible therapeutic applications (GA203/08/0536)

antibiotics has prompted the search for new classes of antimicrobial agents such as antimicrobial peptides (AMPs). We will isolate and characterize novel AMPs from the venom bottle fly larvae, Lucilia sericata. Following t...

CC - Organická chemie

  • 2008 - 2010
    • •
  • 3 957 tis. Kč
    • •
  • 3 957 tis. Kč
    • •
  • GA ČR
Project

Antimicrobial Peptide Produced by Molecular Farming in Barley and Its Use in the Formation of Skin-Applicable Carriers (AMP4SKIN) (TQ03000264)

product and the ability to gradually release active antimicrobial peptide fragmentsThe AMP4SKIN project focuses on using the recombinant human antimicrobial peptide cathelicidin in various commercially available c...

Chemical engineering (plants, products)

  • 2024 - 2025
    • •
  • 5 765 tis. Kč
    • •
  • 4 549 tis. Kč
    • •
  • TA ČR
Project

The role of antimicrobial peptides in plant defense against pahogenic microorganisms (GA522/09/1693)

of them is synthesis of small cationic peptides with antimicrobial activities. Our approach is searchfor novel plant compounds with antimicrobial properties to overcome, modification and synthesis or production of the shor...

EE - Mikrobiologie, virologie

  • 2009 - 2013
    • •
  • 6 823 tis. Kč
    • •
  • 6 823 tis. Kč
    • •
  • GA ČR
Project

Antimicrobial factors in annelids (GA310/04/0806)

groups of factors with antimicrobial activity. (1) Antimicrobial peptides: in annelids, a proline-rich antimicrobial peptide named lumbricin I from the earthworm on isolation of novel antimicrobial

EC - Imunologie

  • 2004 - 2006
    • •
  • 1 430 tis. Kč
    • •
  • 1 430 tis. Kč
    • •
  • GA ČR
Project

Treatment of Infections Caused by Multidrug-Resistant Bacterial Strains by Novel Antibacterial Preparations Based on Cathelicidin Antimicrobial Peptides (NU22-05-00475)

-based polymers. Antimicrobial peptides show a broad range of antimicrobial activityThe increase in antimicrobial resistance is a current worldwide problem for the targeted and long-term release of antimicrobia...

Infectious Diseases

  • 2022 - 2025
    • •
  • 11 376 tis. Kč
    • •
  • 11 376 tis. Kč
    • •
  • MZ
Project

Novel antimicrobial peptides for topical treatment of osteomyelitis and prevention of implant-related infections in orthopedics (NV16-27726A)

Topical application of antimicrobial peptides (AMPs) released from local prepared by the combination of peptides and synthetic bone cement implanted. In the forthcoming experiments we want to find the optimal combination of...

FI - Traumatologie a ortopedie

  • 2016 - 2019
    • •
  • 7 714 tis. Kč
    • •
  • 7 714 tis. Kč
    • •
  • MZ
Project

Development of Novel Ribosome-Targeting Antibiotics (8F19006)

The overall objective is to identify, characterize and optimize molecules as novel lead compounds for the development of novel antimicrobial agents targeting translation.......

Microbiology

  • 2019 - 2022
    • •
  • 5 836 tis. Kč
    • •
  • 5 836 tis. Kč
    • •
  • MŠMT
Project

Induction of antimicrobial peptides in Salmonella-caused gastroenteritis in dependence on type of lipopolysacharide (ME 915)

An experimental model of children Salmonella enteritis will be studied in gnotobiotic piglets. The effect of bacterial lipopolysaccharide in protective intestinal response will be elucidated by the assessment of antimicrobial peptides

EC - Imunologie

  • 2007 - 2011
    • •
  • 1 794 tis. Kč
    • •
  • 1 794 tis. Kč
    • •
  • MŠMT
Project

Development of New Fluorescence Methods for the Characterization of Pores Formed by Antimicrobial Peptides (GAP208/10/1090)

Antimicrobial peptides, AMPs, disrupt biological membranes with the possible consequence of cell death. They have raised much interest as possible alternatives to conventional antibiotics. One main mechanism for the function of AMPs...

CF - Fyzikální chemie a teoretická chemie

  • 2010 - 2012
    • •
  • 2 162 tis. Kč
    • •
  • 2 162 tis. Kč
    • •
  • GA ČR
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