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Projects

5 projects (0,28s) •

Project

Diffusion parameters in the brain and spinal cord during injury (GA309/99/0657)

by cell death and astrogliosis. We shall study how injury-related glial swelling, cell death, astrogliosis and changes in the extracellular matrix affect diffusioin......

FH - Neurologie, neurochirurgie, neurovědy

  • 1999 - 2001
    • •
  • 3 521 tis. Kč
    • •
  • 2 953 tis. Kč
    • •
  • GA ČR
Project

Age-related changes in the structure and function of astrocytes (GA305/08/1384)

We hypothesise that astrogliosis triggers functional changes that impair homeostasis in aged brain. We will exploit a transgenic mouse with intrinsically fluorescent astrocytes that enables the unequivocal identification of these cells by co...

FH - Neurologie, neurochirurgie, neurovědy

  • 2008 - 2009
    • •
  • 2 530 tis. Kč
    • •
  • 2 530 tis. Kč
    • •
  • GA ČR
Project

Membráne properties of astrocytes and the role of extracellular matrix molecules during astrogliosis in the CNS (GA305/02/1528)

Morphological and electrophysiological properties of glial cells are affected by the properties of the extracellular space. The effect of extracellular matrix molecules and intracellular filaments on ionic channels in glial cells have not yet been st...

FH - Neurologie, neurochirurgie, neurovědy

  • 2002 - 2004
    • •
  • 3 472 tis. Kč
    • •
  • 2 932 tis. Kč
    • •
  • GA ČR
Project

The treatment of chronic spinal cord injury using stem cells and enzymes in combination with polymer scaffolds (GA13-00939S)

by astrogliosis evoked by tissue damage. To dissolve the glial scar, bridges will be tested...

FH - Neurologie, neurochirurgie, neurovědy

  • 2013 - 2016
    • •
  • 10 360 tis. Kč
    • •
  • 10 360 tis. Kč
    • •
  • GA ČR
Project

Disturbed regulation of mTOR signaling in glial cells following cerebral ischemia (GA23-06269S)

Protein complexes mTORC1/2 act as a hub for signaling pathways sensing changes in cellular homeostasis, and subsequently affect cellular metabolism and survival. We hypothesize that disruption of mTOR signaling due to insufficient oxygen/glucose supp...

Neurosciences (including psychophysiology)

  • 2023 - 2025
    • •
  • 9 885 tis. Kč
    • •
  • 9 885 tis. Kč
    • •
  • GA ČR
  • 1 - 5 out of 5