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3 (0,116s)

Project

Heme Catabolic Pathway in Chronic Hepatitis C (NT13092)

Heme oxygenase (HMOX), an enzyme induced in response to oxidative stress, catalyzes degradation of pro-oxidative heme to carbon monoxide (CO), iron and biliverdin, which is reduced to bilirubin by biliverdin reductase A (BVRA). Hepa...

FP - Ostatní lékařské obory

  • 2012 - 2015
  • 4 323 tis. Kč
  • 4 323 tis. Kč
  • MZ
Project

NEW POSSIBILITIES IN THERAPY OF HIV/AIDS DISEASE ROLE OF HEME OXYGENASE, BILIVERDIN REDUCTASE AND THE EFFECTS OF HEME ARGINATE ON REPLICATION AND REACTIVATION OF HIV-1 (NT14135)

Goals of the project: 1/ To verify and further study effects of HA on HIV-1 replication and reactivation observed in cell lines also in primary PBMC's: a/ To verify HA effect on acute infection of PBMC's of healthy donors with HIV-1 b/ To study HA ef...

EE - Mikrobiologie, virologie

  • 2013 - 2015
  • 6 216 tis. Kč
  • 6 084 tis. Kč
  • MZ
Project

Structural Study of Potentially Bioactive Bile Pigment Complexes Relation to their Protective Function in Organisms (GAP206/11/0836)

The project focuses on discovering the connections between the protective functions of bile pigments and the spatial arrangement of their complexes. The proposed project will newly employ advanced analytical chiroptical methods inherently sensitive t...

CB - Analytická chemie, separace

  • 2011 - 2014
  • 4 424 tis. Kč
  • 4 424 tis. Kč
  • GA ČR
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