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1 103 (0,147s) •

Project

The use of affinity chromatography for identification of sterol-binding proteins from plants (IAA4055204)

and which affinity. Data will serve for optimization of steroid structures to prepare high-affinity binding matrices for plant PBPs, their isolation and study. questions about the mode of steroid-binding and trans...

CC - Organická chemie

  • 2002 - 2006
    • •
  • 4 941 tis. Kč
    • •
  • 2 661 tis. Kč
    • •
  • AV ČR
Project

Molecular mechanism of interaction between the H4-H5 loop of Na+/K+-ATPase and the binding site for cardiac glycosides (IAA7011801)

) and low (E2) affinity ATP binding sites coexist at the functional Na+/K+ complex. There is not clear, yet, whether one binding site has different affinities during the transport which is also called a receptor fo...

BO - Biofyzika

  • 1998 - 2000
    • •
  • 1 852 tis. Kč
    • •
  • 1 075 tis. Kč
    • •
  • AV ČR
Project

Are the High and Low Affinity ATP Binding Sites of Na,K-ATPase Different or Identical? (GA204/95/0624)

CE - Biochemie

  • 1995 - 1997
    • •
  • 750 tis. Kč
    • •
  • 750 tis. Kč
    • •
  • GA ČR
Project

Efficient free energy and enhanced sampling calculations of protein-­‐protein interactions (GF15-34684L)

binding to the 14-­‐3-­‐3 are intrinsically disordered, and the affinity for many, allowing for an efficient prediction of binding affinities. tools to compute the binding free energy for complex protein ...

CF - Fyzikální chemie a teoretická chemie

  • 2015 - 2017
    • •
  • 6 221 tis. Kč
    • •
  • 6 221 tis. Kč
    • •
  • GA ČR
Project

Chemical modification of bambusurils for adjusting their binding affinity and selectivity (GA23-05271S)

in bambusurils which will bind anions based on their shape and size and not on their solvation energy. The binding affinity of the prepared bambusuril toward inorganicBambusurils are macrocyclic compounds known for their a...

Organic chemistry

  • 2023 - 2025
    • •
  • 6 054 tis. Kč
    • •
  • 5 931 tis. Kč
    • •
  • GA ČR
Project

Preparation of lectins with high specificity and affinity (GPP207/11/P185)

to bind carbohydrates with very high affinity and specificity, are called lectins patients. One of the lectin displays an affinity for fucose in micromolar range, unusually high for monosaccharides binding. Search...

BO - Biofyzika

  • 2011 - 2014
    • •
  • 1 839 tis. Kč
    • •
  • 1 839 tis. Kč
    • •
  • GA ČR
Project

Protein Affinity and Selectivity to Cellular Membranes (GA20-20152S)

. The aim of the proposed project is to identify, quantify, and explain protein affinity method to determine the binding free energy of proteins and their mutants to specific on amphiphilic helices, a frequent membrane binding

Physical chemistry

  • 2020 - 2022
    • •
  • 8 105 tis. Kč
    • •
  • 8 105 tis. Kč
    • •
  • GA ČR
Project

Interactions of mutant forms of cryptogein with a membrane binding site biosensors-based characterisation (GAP501/11/1003)

of elicitins by high affinity binding site on plasma membrane has not been fully described. An attempt to isolate the high affinity binding site will be done as well.......

CE - Biochemie

  • 2011 - 2016
    • •
  • 6 228 tis. Kč
    • •
  • 6 228 tis. Kč
    • •
  • GA ČR
Project

The role of T- and R-conformations of insulin in binding to the insulin receptor (GPP207/11/P430)

is to elucidate the role of T/R insulin structures in binding affinity to the IR.. Insulin is known to act through binding to the insulin receptor (IR); however must undergo structural changes in the C-terminus of the B-ch...

CE - Biochemie

  • 2011 - 2013
    • •
  • 2 554 tis. Kč
    • •
  • 2 554 tis. Kč
    • •
  • GA ČR
Project

Unveiling Divergence and Convergence Points in Coronavirus Evolution for Host Receptor Recognition (GM25-17643M)

' receptor binding domains (RBDs), which play a crucial role in viral entry and infection to affinity maturate multiple coronaviral RBD domains. Through deep sequencing and comprehensive characterization, we aim to map key residues ...

Virology

  • 2025 - 2029
    • •
  • 24 949 tis. Kč
    • •
  • 24 949 tis. Kč
    • •
  • GA ČR
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