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11 (0,079s) •

Project

Preparation of discrete photon-upconversion nanoparticle bioconjugates (LD15023)

of this project are to prepare well-defined bioconjugates of photon-upconversion nanoparticles-defined bioconjugates are applied. Therefore, UCNPs modified by single biomolecule bioconjugates will be evaluated within the n...

CB - Analytická chemie, separace

  • 2016 - 2017
    • •
  • 1 263 tis. Kč
    • •
  • 1 263 tis. Kč
    • •
  • MŠMT
Project

Bioconjugation reactions for cross-linking of proteins to DNA (GA18-03305S)

We plan to develop new bioconjugation reactions for specific cross-linking of proteins to DNA. We will design and synthesize novel nucleotides and nucleoside triphosphates bearing reactive groups capable of specific conjugation reactions wit...

Organic chemistry

  • 2018 - 2022
    • •
  • 6 012 tis. Kč
    • •
  • 5 301 tis. Kč
    • •
  • GA ČR
Project

Development of fluoroalkylated hypervalent iodine reagents for thiol bioconjugations (GA17-00598S)

Postsynthetic modification of biomolecules by bioconjugation is a powerful research and technological tool. Traditional methods available for thiol bioconjugation are based on Michael addition, alkylation, or disulfide formation and...

CC - Organická chemie

  • 2017 - 2019
    • •
  • 6 086 tis. Kč
    • •
  • 4 499 tis. Kč
    • •
  • GA ČR
Project

Tuning of electrochemical properties of boron polyhedral by advanced substitutions towards their use in bioconjugates systematic basic research (GA19-04630S)

candidates for a new type of bioconjugates detectable by electrochemical and other that retain the specific electrochemical response even after bioconjugation.......

Biomaterials (as related to medical implants, devices, sensors)

  • 2019 - 2021
    • •
  • 7 981 tis. Kč
    • •
  • 7 908 tis. Kč
    • •
  • GA ČR
Project

Development of new bioorthogonal reactions (GJ15-06020Y)

criteria of modern bioconjugation reactions. By systematic screening of reaction combinations of reagents with superior properties for development of novel bioconjugation or proteins) will provide powerful strategy for construction...

CC - Organická chemie

  • 2015 - 2017
    • •
  • 5 716 tis. Kč
    • •
  • 5 716 tis. Kč
    • •
  • GA ČR
Project

Research and development of innovative methods for protein characterisation and bioconjugation (CF PROT) (EG21_374/0026531)

an azidofluoroalkyl group to proteins for bioconjugation applications in pharmacy....

Chemical engineering (plants, products)

  • 2022 - 2023
    • •
  • 5 187 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • MPO
Project

Bioconjugates of nanoparticles as new carriers of 223Ra for targeted alpha radiotherapy (8J20PL016)

of the bioconjugates, their characterization, and verification of their stability and efficiency...

Inorganic and nuclear chemistry

  • 2020 - 2022
    • •
  • 201 tis. Kč
    • •
  • 201 tis. Kč
    • •
  • MŠMT
Project

Expanding the linear paradigm of the polymethine dyes (GJ20-30004Y)

and compatibility with model bioconjugation modalities, will provide further inputs...

Organic chemistry

  • 2020 - 2023
    • •
  • 5 279 tis. Kč
    • •
  • 5 279 tis. Kč
    • •
  • GA ČR
Project

Center of targeted therapeutic drugs (1M0505)

and immunotherapeutic instruments. A practical output will be a polyfunctional bioconjugate by the organism (bioconjugates, targeted drugs). Verification of anti-tumour effects in v......

EI - Biotechnologie a bionika

  • 2005 - 2011
    • •
  • 225 617 tis. Kč
    • •
  • 200 673 tis. Kč
    • •
  • MŠMT
Project

Sensitive bioanalytical tools for the surveillance of honey bee diseases (LTAB19011)

We will design a new bioanalytical tool for the early-stage detection of bacterial pathogens in order to prevent honey bee colony losses. The first aim of the project is the development of antibody against Paenibacillus larvae, the causative agent o...

Analytical chemistry

  • 2019 - 2021
    • •
  • 1 200 tis. Kč
    • •
  • 1 200 tis. Kč
    • •
  • MŠMT
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