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31 (0,082s) •

Project

Study of chemism and biodistribution of 99mTc lebelled peptides for imaging of peripheral receptors (GA203/97/0342)

compounds which have to possess suitable radiochemical purity, the biodistribution in situ will be described. For promising analogues, a biodistribution study......

CH - Jaderná a kvantová chemie, fotochemie

  • 1997 - 1999
    • •
  • 1 363 tis. Kč
    • •
  • 878 tis. Kč
    • •
  • GA ČR
Project

Novel approaches towards anti - HIV -1 DNA vaccine (ME 875)

study of biodistribution of DNA/Gal-lipolex complexes and immunity response to gp120+MBLDNA/Gal-lipolex immunisation, comparison of HIV-- glycosylation concensus B gp 120 antigene exprimed in different tissue cells......

EC - Imunologie

  • 2006 - 2009
    • •
  • 1 785 tis. Kč
    • •
  • 1 685 tis. Kč
    • •
  • MŠMT
Project

The study of (18F) fluorothymidine preparation and verification of its pharmacokinetics in the PET studies (NL7688)

and chemical purity of the synthesized product. Performing the introductory biodistribution...

FR - Farmakologie a lékárnická chemie

  • 2003 - 2005
    • •
  • 10 703 tis. Kč
    • •
  • 5 743 tis. Kč
    • •
  • MZ
Project

Preparation and redioactive labelling of low-molecular weigth proteins and peptides with tissue-specific distribution (NL6071)

biodistribution into pathologically altered tissues are expected. These substances may play...

FR - Farmakologie a lékárnická chemie

  • 2000 - 2002
    • •
  • 1 746 tis. Kč
    • •
  • 1 745 tis. Kč
    • •
  • MZ
Project

Radiolabelled neuropeptides for cancer diagnosis and treatment (GAP304/10/1738)

of biodistribution characteristics, transport parameters and elimination mechanisms in laboratory...

FR - Farmakologie a lékárnická chemie

  • 2010 - 2012
    • •
  • 2 190 tis. Kč
    • •
  • 2 190 tis. Kč
    • •
  • GA ČR
Project

Study of pharmacokinetics and biodistribution of radiolabelled biologically active peptides in laboratory animals (OC B12.001)

The aim of this project is to receive new knowledge about preparation and biological behaviour of the radiolabelled receptor-specific peptides with the intention to find new radiodiagnostics or radiotherapeutics of tumours under endocrine control.For...

FR - Farmakologie a lékárnická chemie

  • 2001 - 2004
    • •
  • 5 106 tis. Kč
    • •
  • 1 752 tis. Kč
    • •
  • MŠMT
Project

Biodistribution and real-time monitoring of free or apoferritin-encapsulated charged cholinesterase reactivators (GA22-14568S)

Oxime cholinesterase reactivators are used for life endangering intoxications caused by organophosphate agents. However, clinically used (so called charged reactivators) or experimental uncharged reactivators have very limited penetration to central ...

Toxicology

  • 2022 - 2024
    • •
  • 11 763 tis. Kč
    • •
  • 11 208 tis. Kč
    • •
  • GA ČR
Project

Detoxification of quaternary isoquinoline alkaloids in vitro and in vivo, biological activity of their metabolites (GA525/07/0871)

, we will study biodistribution of metabolites and their effect on vital...

GH - Výživa hospodářských zvířat

  • 2007 - 2010
    • •
  • 4 922 tis. Kč
    • •
  • 4 922 tis. Kč
    • •
  • GA ČR
Project

FIT (Pharmacology, Immunotherapy, nanoToxicology) (EF15_003/0000495)

The objectives are: To create a robust instrumental base for in vivo imaging of biocompatible nanoparticles to understand the biodistribution dynamics in different places of the organism To establish a robust basis for evaluation of nanoto...

EE - Mikrobiologie, virologie

  • 2016 - 2022
    • •
  • 202 887 tis. Kč
    • •
  • 202 887 tis. Kč
    • •
  • MŠMT
Project

Targeted cancer radiotherapy in preclinical experiment (OC08006)

The objective of this project is an acquirement of new theoretical findings concerning biological behaviour of radiopharmaceuticals developed for diagnosis and therapy of cancer and basis for the use of these potential pharmaceuticals in clinical pra...

FR - Farmakologie a lékárnická chemie

  • 2008 - 2011
    • •
  • 4 900 tis. Kč
    • •
  • 2 800 tis. Kč
    • •
  • MŠMT
  • 1 - 10 out of 31