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8 902 (0,187s) •

Project

Biophysical properties of the (guanine+cytosine) blocks and the (adenine+thymine) blocks in the human chromosome molecules of DNA (IAA1004201)

Assess biophysical properties of the longest (G+C) and (A+T) blocks of the human genome. Identify nucleotide sequences introducing RNA-like properties into DNA for their secondary structure modeling of the whole

BO - Biofyzika

  • 2002 - 2006
    • •
  • 6 327 tis. Kč
    • •
  • 3 013 tis. Kč
    • •
  • AV ČR
Project

Biophysical Properties of Biologically and Medically Important Regions of Human DNA (IAA100040701)

approaches conformational properties of DNA motifs occurring in the human genome regions for. Themapping of DNA conformational properties and understanding of their rules in relationDNA can exist in confo...

BO - Biofyzika

  • 2007 - 2011
    • •
  • 3 725 tis. Kč
    • •
  • 3 725 tis. Kč
    • •
  • AV ČR
Project

Biophysical analysis of selected regions of the human genome (IAA5004802)

of the conformational properties of DNA along the human genome with the distribution of the oligonucleotides coding for these properties, and the genome genetic map. A further method-induced damage in DNA to its c...

BO - Biofyzika

  • 1998 - 2002
    • •
  • 7 736 tis. Kč
    • •
  • 2 387 tis. Kč
    • •
  • AV ČR
Project

Biophysical analysis of DNA interactions with antitumor ruthenium complexes (GA204/97/P028)

of the platinum group including ruthenium complexes is DNA. The main topic of this project is therefore the study of a ruthenium complexes influence on DNA properties by using modernmethods of molecular biophysics...

CE - Biochemie

  • 1997 - 1999
    • •
  • 659 tis. Kč
    • •
  • 479 tis. Kč
    • •
  • GA ČR
Project

Interactions of supercoiled DNA with tumor-supressor protein p53 (IAA5004803)

and some agents damaging DNA. b) Complex biophysical studies of active and inactiveThis project is oriented towards the biophysical studies of p53 and its interactions with DNA understanding of which we feel to be...

EB - Genetika a molekulární biologie

  • 1998 - 2000
    • •
  • 2 899 tis. Kč
    • •
  • 990 tis. Kč
    • •
  • AV ČR
Project

Centre of Biophysical Chemistry, Bioelectrochemistry and Bioanalysis. New Tools for Genomics, Proteomics and Biomedicine. (LC06035)

world science is oriented towards utilization of electrochemical DNA detection in thisanalysis. DNA electroactivity was discovered at the Institute of Biophysics in Brno the research of electrochemical DNA sensors...

CG - Elektrochemie

  • 2006 - 2011
    • •
  • 55 154 tis. Kč
    • •
  • 55 124 tis. Kč
    • •
  • MŠMT
Project

Mechanical properties of RNA and DNA structural building blocks (GA17-14683S)

laboratories. The results will elucidate mechanical properties of DNA and RNA structuralNatural and artificial RNA and DNA structures are composed of recurrent building blocks. The project is focused on inferring mechanica...

BO - Biofyzika

  • 2017 - 2021
    • •
  • 4 017 tis. Kč
    • •
  • 3 756 tis. Kč
    • •
  • GA ČR
Project

Biophysics and bioinformatics of the regions in the human genome with extreme nucleotide distributions (GA202/07/0094)

demonstrate  that such molecules exhibit dramatically different biophysical properties than the common DNA containing all four nucleotides. In this project, we propose, mouse and other genomes and their representative exam...

BO - Biofyzika

  • 2007 - 2009
    • •
  • 2 815 tis. Kč
    • •
  • 2 815 tis. Kč
    • •
  • GA ČR
Project

Metallo-supramolecular helicates as DNA condensing agents and carriers for DNA delivery (GA20-00735S)

biophysics to thoroughly explore the DNA binding properties of the helicates as well, unique DNA binding properties and, as we have previously demonstrated, they can which can bind to DNA and dif...

Biophysics

  • 2020 - 2022
    • •
  • 4 590 tis. Kč
    • •
  • 4 590 tis. Kč
    • •
  • GA ČR
Project

Translesion DNA synthesis across lesions induced by agents of biological significance. An insight into energetics, kinetics and mechanism (GA17-09436S)

by molecular biophysics methods will be used. These are ideal modified DNA model systemsThe biological effects of DNA-damaging physical and chemical agents are associated with their ability to affect DNA replicati...

BO - Biofyzika

  • 2017 - 2019
    • •
  • 5 627 tis. Kč
    • •
  • 5 006 tis. Kč
    • •
  • GA ČR
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