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1 680 (0,088s)

Project

Antisense and sense RNA targeting of chalcone synthase - related sequences study of genes involved in bitter acid biosynthesis in hop (H. lupulus) (GA521/99/1591)

of biosynthesis of bitter acids in hop (Zuurbier et al.:Phytochemistry,38:77,1995). Based to blocking of a group of CHS-related genes. This blocking should causchanges of bitter acids and anthocyanin ...

EB - Genetika a molekulární biologie

  • 1999 - 2001
  • 6 258 tis. Kč
  • 4 474 tis. Kč
  • GA ČR
Project

Aspects of proteomics of chalcone synthases and chalcone synthase-like proteins in hop important for lupulin biosynthesis (GP521/06/P323)

represent the crucial components of biosynthetic pathways of bitter acids and prenylatedHop (Humulus lupulus L.) is a source of +-acids and aromatic compounds for beer industry. Nowadays many compounds isolated from hop ar...

EB - Genetika a molekulární biologie

  • 2006 - 2008
  • 1 200 tis. Kč
  • 1 200 tis. Kč
  • GA ČR
Project

Functional genomics of hop (H. lupulus L.) with respect to genes co-determining lupulin production (GA521/03/0072)

It is proposed to analyse structural and functional aspects of genomic organization of chalcone synthase (chs) homologues, which have been found recently to be involved in biosynthesis of bitter acids valuable for bitte...

EB - Genetika a molekulární biologie

  • 2003 - 2005
  • 5 517 tis. Kč
  • 2 944 tis. Kč
  • GA ČR
Project

Combinatorial regulation and network of transcription factors involved in the biosynthesis of medicinal prenylflavonoids in hop (Humulus lupulus L.). (GA13-03037S)

Hop is source of bitter acids and medicinal prenylchalcones, including xanthohumol. During last years we have characterized lupulin-specific chalcone synthase in a transcription activating complex regulating this key enzyme of preny...

EB - Genetika a molekulární biologie

  • 2013 - 2017
  • 14 323 tis. Kč
  • 14 323 tis. Kč
  • GA ČR
Project

Significance of hop beta acids for Czech beers (QI91B227)

Determination of importance of hop beta acids for Czech beers is the topic proved that structural changes of beta acids during brewing process are different fromalpha acids. Practically quantitative oxidation of beta ac...

CB - Analytická chemie, separace

  • 2009 - 2013
  • 7 776 tis. Kč
  • 7 776 tis. Kč
  • MZe
Project

The potential of xanthohumol and beta-bitter acids in the therapy of nosocomial infections (NV17-31765A)

utilized together with antibiotics. Certain compounds from hops, especially beta-bitter acids and xanthohumol possess strong inhibitory effects on Gram-positive......

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2017 - 2020
  • 11 693 tis. Kč
  • 11 164 tis. Kč
  • MZ
Project

Analysis of replication and maintenance functions of plasmid vectors and of the amino acids biosynthesis genes in coryneform bacteria (IAA520407)

CE - Biochemie

  • 1994 - 1996
  • 442 tis. Kč
  • 676 tis. Kč
  • AV ČR
Project

Molecular analysis of transcription factors of hop (H. lupulus L.) in relation to lupulin biosynthesis (GA521/08/0740)

Previously we characterized an oligofamily chalconsynthase genes chs_H1 from hop, expressed in glandular tissue and  involved in production of "medicinal" prenylflavonoids and bitter acids important in brewing idustry. We also initi...

EB - Genetika a molekulární biologie

  • 2008 - 2011
  • 4 453 tis. Kč
  • 4 453 tis. Kč
  • GA ČR
Project

Optimization of Characteristics of Plasmid Vectors from Coryneform Bacteria and Their Use for the Analysis of Amino Acids Biosynthesis Genes. (GA204/94/1737)

EE - Mikrobiologie, virologie

  • 1994 - 1996
  • 710 tis. Kč
  • 1 103 tis. Kč
  • GA ČR
Project

Genetic analysis of biosynthesis of essential amino acids valine, leucine and isoleucine in Corynebacterium glutamicum (GA525/01/0916)

The branched-chain amino acids - valine, leucine, and isoleucine are essential for animals and human. Utilization of environmentally clean bacterial fermentation in industrial productions of amino acids, applied particularly as addi...

EB - Genetika a molekulární biologie

  • 2001 - 2003
  • 3 369 tis. Kč
  • 1 983 tis. Kč
  • GA ČR
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