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496 (0,096s)

Project

Prevention and treatment of the orthopedic infections with injectable resorbable bone substitute gradually releasing pathogen-specific antimicrobial compounds (NW24-05-00202)

Bone defects with significant bone loss, such as open fractures, alloplasty revisions, bone infections requiring debridement or bone resection due to bone tumor of these injuries remains unsatisfactory.

Biomaterials (as related to medical implants, devices, sensors)

  • 2024 - 2027
  • 14 880 tis. Kč
  • 14 880 tis. Kč
  • MZ
Project

Bone turnover by osteoporosis and effect of therapy - assessment by dynamic bone scintigrphy (NG13)

For differential diagnosis and therapy of osteoporosis,it is important to assess bone turnover,The above-mentioned original method of dynamic bone scintigraphy,which assesses the metabolic activity of bone,could aid in maki...

FE - Ostatní obory vnitřního lékařství

  • 1998 - 2000
  • 437 tis. Kč
  • 419 tis. Kč
  • MZ
Project

High-resolution microCT FE-models of cancellous bone structure and their application to selected problems in biomechanics (GP103/07/P483)

Structural properties of trabecular bone play an important role in bone quality assessment. Bone quality is a term associated with fracture risk and together with other factors, such as bone mineral density (BMD), ...

FI - Traumatologie a ortopedie

  • 2007 - 2009
  • 727 tis. Kč
  • 727 tis. Kč
  • GA ČR
Project

Importance of local blood flow in bone tissue remodelation in rats-relations between bone blood circulation and bone metabolism.Hormonal regulations and other influences in model situations (NK5886)

Experimental study of relations of bone blood flow and bone tissue remodelation in laboratory conditions,caused by hormonal influence and by influence of other agents of bone blood floow mechanisms (prostaglandins,nitric ox...

FP - Ostatní lékařské obory

  • 2000 - 2002
  • 2 302 tis. Kč
  • 2 302 tis. Kč
  • MZ
Project

Synthetical biocompatible degradable materials at bone defect healing in childhood (NS9860)

The aim of the project is to compare speed and quality of bone defect healing with biomaterial application (ChronOs) and with biomaterial in combination with own bone marrow as the stem cells holder to accelerate bone defec...

FI - Traumatologie a ortopedie

  • 2008 - 2010
  • 958 tis. Kč
  • 958 tis. Kč
  • MZ
Project

Influence of the inner and middle ear pathology on the bone conduction of the sound waves (NK5871)

The origin and mechanism of Carhart´s notch from the point of different order of stapes fixation; Carhart notch and electric bone-conduction audiometry.Direct measurement of bone conduction;Intraoperative bone conduction au...

FF - ORL, oftalmologie, stomatologie

  • 2000 - 2002
  • 1 924 tis. Kč
  • 1 924 tis. Kč
  • MZ
Project

Effects of estrogen status on mechanical properties and biochemical markers of bone turnover in male rats. (NB7508)

Osteoporotic changes in bone are characterized by changes in both density and structure. Little is known about the effects of estrogen on bone metabolism and bone want to use bending tests, biochemical markers of bone

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2003 - 2005
  • 1 021 tis. Kč
  • 1 004 tis. Kč
  • MZ
Project

Synthetic biocompatible degradable materials in the treatment of juvenile bone cysts (NR8475)

The aim of the project is to compare a therapy of juvenile bone cysts by miniinvasive cyst filling with resorbable biocompatible synthetic material with contingent application of bone marrow with the present method of methyprednisol...

FI - Traumatologie a ortopedie

  • 2005 - 2007
  • 1 042 tis. Kč
  • 1 029 tis. Kč
  • MZ
Project

Biomarkers of Bone Metastatic Disease (NT13655)

The subject of the study is a measurement of circulating levels of novel bone-turnover biomarkers and their comparison to the the traditional markers before for the measurements of bone turnover biomarkers measurements in oncology p...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2012 - 2015
  • 3 559 tis. Kč
  • 3 559 tis. Kč
  • MZ
Project

Signalling pathways in myeloma bone disease (NT14393)

The aim of the project is to improve diagnostics and monitoring of myeloma bone material (blood serum and bone marrow plasma). In selected patients we will perform bone biopsy with the correlation of bone metabolis...

FD - Onkologie a hematologie

  • 2013 - 2015
  • 3 036 tis. Kč
  • 3 036 tis. Kč
  • MZ
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