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852 (0,097s) •

Project

Correlation of MR spectroscopy image of hippocampus region and impairment of cognitive functions in patients after brain irradiation (NT14600)

In order to optimalize the treatment of patients with brain metastases, mainly of this region of brain is said to be responsible for the development of late undesirable functions examination, also evaluation of ongoing chan...

FD - Onkologie a hematologie

  • 2013 - 2015
    • •
  • 3 685 tis. Kč
    • •
  • 3 685 tis. Kč
    • •
  • MZ
Project

Strategies for specific targeting of brain metastasis microenvironment for diagnostic and therapy (NU22-03-00318)

Brain metastases affect approximately 20% of patients with various solid the hypothesis that FAP is a potential diagnostic and therapeutic target in brain metastases. We will determine the quantity and localization...

Radiology, nuclear medicine and medical imaging

  • 2022 - 2025
    • •
  • 12 326 tis. Kč
    • •
  • 12 326 tis. Kč
    • •
  • MZ
Project

Neoadjuvant Stereotactic Radiotherapy for Brain Metastasis - prospective trial NeoSTROBE (NW25-03-00278)

The main methods of treatment for brain metastases are radiotherapy and surgical resection. Among the radiation techniques, whole brain radiotherapy (WBRT) and targeted stereotactic radiotherapy (SRT) are used. In patients ...

Oncology

  • 2025 - 2028
    • •
  • 11 980 tis. Kč
    • •
  • 11 980 tis. Kč
    • •
  • MZ
Project

Structural MRI radiomic analysis for differential diagnosis of radiation injury and true progression after stereotactic radiotherapy of brain metastases (NU22-03-00159)

of incidence of patients with brain metastases indicated to SRT. Exact and valid evaluation of brain metastases in terms of differential diagnosis of radiotherapy-related changesStereotactic radiotherapy (SRT) is ...

Oncology

  • 2022 - 2025
    • •
  • 7 016 tis. Kč
    • •
  • 7 016 tis. Kč
    • •
  • MZ
Project

Extension of established prognostic scores in brain metastases by microRNA profiling to tailor the post-operative personalized care (NV18-03-00398)

Brain metastases (BM) are the most often occurring intracranial tumors characterized by an unfavorable prognosis. Therapeutic options are limited and depend largely on the prognosis of patient which is currently predicted using prog...

Oncology

  • 2018 - 2022
    • •
  • 12 078 tis. Kč
    • •
  • 11 599 tis. Kč
    • •
  • MZ
Project

Reaction of hippocampal neuronal population on stereotactic radiotherapy of extratemporal brain metastases The influence on the neurocognitive function and maintanance of quality of life (NV18-03-00469)

Quality of life (QoL) is currently emphasized during the treatment of bran metastases (BM). Stereotactic radiotherapy and radiosurgery (SRT/SRS) is an advanced technique that – apart from excellent local control – also induces less adverse e...

Oncology

  • 2018 - 2023
    • •
  • 7 086 tis. Kč
    • •
  • 6 999 tis. Kč
    • •
  • MZ
Project

Analysis of the regressive alterations in lymphatic metastases of lung cancer after an inductive therapy (NR7772)

Analysis of the regressive alterations in bioptically verified lymphatic metastases of lung cancer after a neoadjuvant chemotherapy will check the supposed effect of the pre-operative chemotherapy on lymphogenous dissemination of advanced tu...

FC - Pneumologie

  • 2004 - 2006
    • •
  • 1 602 tis. Kč
    • •
  • 1 532 tis. Kč
    • •
  • MZ
Project

Increasing of colorectal carcinoma liver metastases resectability by combined, staged procedures. (NR8301)

The subject of grant is increasing of resectability of colorectal carcinoma liver metastases. The methods of project will be in evaluation of general health status of patien t, his or her liver functions, the volume and number of liver m...

FJ - Chirurgie včetně transplantologie

  • 2005 - 2007
    • •
  • 3 285 tis. Kč
    • •
  • 2 975 tis. Kč
    • •
  • MZ
Project

Radiofrequency Destruction of Nuclear Metastases (NC7499)

Minimally invasive destruction of liver metastases of colorectal carcinoma by means of a radiofrequency systems. The creation of group of patients, the setting up of a set of rules for their selection, evalution of the results of treatment.....

FD - Onkologie a hematologie

  • 2003 - 2005
    • •
  • 1 214 tis. Kč
    • •
  • 1 201 tis. Kč
    • •
  • MZ
Project

Influence of non-ana tomical limited resections of liver metastases on the survival rate in patients with colorectal carcinoma (IZ4154)

Resections of liver metastases in colorectal carcinoma, to determine diagnostic and therapeutical criterions in all patients with this diagnosis. An endeavour to demostrate positive influence of surgical treatment on the survival rate in the...

FJ - Chirurgie včetně transplantologie

  • 1997 - 1999
    • •
  • 1 296 tis. Kč
    • •
  • 1 147 tis. Kč
    • •
  • MZ
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