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1 535 (0,074s) •

Project

PRODUCTION OF RECOMBINANT IMMUNOCYTOKINES FOR TUMOR IMMUNOTHERAPY (IAA500200712)

Effective cancer theraphy through immunomodulation is one of the most important long-term goal of imunology. Although IL-2 and IL-12, one of the most promising cytokines for tumor immunotheraphy, have been extensively tested in many...

EC - Imunologie

  • 2007 - 2011
    • •
  • 4 725 tis. Kč
    • •
  • 4 725 tis. Kč
    • •
  • AV ČR
Project

Generation of focused shock waves by pulse electrical discharges in water and their application in medicine (IBS2043004)

Generation of focused shock waves by pulse electrical discharges in water which are able to destroy an acoustically homogeneous tissue locally by the action of cavitation originated just near focal point of the shock wave. Due to the dependence of so...

BL - Fyzika plasmatu a výboje v plynech

  • 2000 - 2003
    • •
  • 14 247 tis. Kč
    • •
  • 9 680 tis. Kč
    • •
  • AV ČR
Project

Changes of the cytoskeleton in tumour cell lines during induced apoptosis in relation to different stages of differentiation (GA304/00/0403)

Apoptosis, a programmed cell death, is worth of study not only as aform of physiological cell death but also as a promising approach to the casual theraphy of malignant diseases. In spite of great progress in this field is not well understoo...

EA - Morfologické obory a cytologie

  • 2000 - 2002
    • •
  • 1 520 tis. Kč
    • •
  • 1 120 tis. Kč
    • •
  • GA ČR
Project

Microparticle dosage form for theraphy of nonspecific inflammatory bowel diseases (NS10222)

Pharmacotherapy of inflammatory bowel disease is long-term, often lifelong, accompanied with side-effects, which are a consequence of high doses of administered drugs and their systemic absorption in small intestine. Development of drug microform, th...

FR - Farmakologie a lékárnická chemie

  • 2009 - 2010
    • •
  • 523 tis. Kč
    • •
  • 523 tis. Kč
    • •
  • MZ
Project

Circulating microvesicles (microparticles and exosomes) for diagnosis of gynecological malignancies (NT12248)

of gynecological cancer. The aim of the project is to identify molecular characteristics of plasma circulating ovarian cancer and endometrial cancer specific microvesicles. To identify cancer specific biomarkers w...

FK - Gynekologie a porodnictví

  • 2011 - 2015
    • •
  • 6 321 tis. Kč
    • •
  • 6 321 tis. Kč
    • •
  • MZ
Project

Role of exosomes in information transfer between cancer-associated fibroblasts and cancer cell, with emphasis on malignant melanoma (GA19-05048S)

Cancer incidence is increasing worldwide, but mainly in developed countries research and data of other authors demonstrated a remarkable role of cancer microenvironment on growth and spreading of malignant tumors with important role...

Oncology

  • 2019 - 2021
    • •
  • 12 364 tis. Kč
    • •
  • 11 878 tis. Kč
    • •
  • GA ČR
Project

Induction of pyroptosis in cancer cells - potential therapeutic method for pancreatic cancer (FW01010527)

cancer. Developed agent will be based on induction of proinflammatory cell death - pyroptosis - in pancreatic cancer cells. Adeno-associated viral vectors (AAV innovative approach to biological treament of cancer. The appr...

Biochemistry and molecular biology

  • 2020 - 2024
    • •
  • 11 252 tis. Kč
    • •
  • 6 072 tis. Kč
    • •
  • TA ČR
Project

BRCA1 alternative splicing variants and their prognostic and predictive role in breast cancer (NT12280)

cancer. cDNA will be synthesized from RNA isolated from mammary tissue samples receivedfrom breast cancer patients and from women without breast cancer and from with breast cancer and controls will be statisticall...

FD - Onkologie a hematologie

  • 2011 - 2014
    • •
  • 5 159 tis. Kč
    • •
  • 5 159 tis. Kč
    • •
  • MZ
Project

Characterization of metalloproteins important in cancer their interactions with DNA (OC D21.002)

Characterization of metalloproteins important in cancer their interactions with DNA...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2002 - 2005
    • •
  • 3 290 tis. Kč
    • •
  • 1 265 tis. Kč
    • •
  • MŠMT
Project

ProstaPilot. Prostate cancer screening with abbreviated MRI protocol (NU22-09-00539)

Prostate cancer is one of the most common cancers in men, comparable in incidence and mortality to breast cancer in women. Not all cancers have the potential to cause harm to health; these clinically non-significan...

Oncology

  • 2022 - 2025
    • •
  • 6 455 tis. Kč
    • •
  • 6 455 tis. Kč
    • •
  • MZ
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