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25 (0,082s) •

Project

Nanofibre mesh with the admixture of cannabinoids for the treatment of wounds after extensive surgery (FV30362)

The object of the project is the research and realization of mesh (grid) based on nanofiber blended with cannabinoids. The main objective of the project is to optimize the technological process and production technology nets for therapeutic ...

Transplantation

  • 2018 - 2022
    • •
  • 18 096 tis. Kč
    • •
  • 12 656 tis. Kč
    • •
  • MPO
Project

Elaboration of methodology for screening and confirmation of synthetic cannabinoids in biological material (VI20192022168)

Prison Service of ČR does not yet have reliable screening method for new synthetic drugs, which can be used for their illegal prison distribution and abuse. It is therefore desirable to develop methodology for suitable biological matrix analysis allo...

Public and environmental health

  • 2019 - 2022
    • •
  • 8 697 tis. Kč
    • •
  • 8 697 tis. Kč
    • •
  • MV
Project

Creation of standards for the evaluation of the eligibility to drive after cannabis consumption evaluation of cannabinoid blood levels relevant to the time of use, psychomotor performance, vigility (VG20122015080)

We will evaluate psychomotor functions in recreational and chronic cannabis users after acute cannabis consumption. Psychomotor attenuation will be correlated with blood levels of cannabinoids to ascertain the reliable plasma limit associate...

FL - Psychiatrie, sexuologie

  • 2012 - 2015
    • •
  • 20 733 tis. Kč
    • •
  • 20 726 tis. Kč
    • •
  • MV
Project

Molecular Mechanism of Cannabinoid Receptor 1 Signaling Modulation by SGIP1 (GA16-24210S)

Certain diseases of the nervous system are accompanied by alterations in synaptic functions. Synaptic plasticity mediated by the endogenous cannabinoid system involves the activation of the Cannabinoid Receptor 1 (CB1R). The princip...

FR - Farmakologie a lékárnická chemie

  • 2016 - 2020
    • •
  • 9 453 tis. Kč
    • •
  • 8 229 tis. Kč
    • •
  • GA ČR
Project

The role of SGIP1 in modulation of nociception via Cannabinoid receptor 1 (GA21-02371S)

Treatment of chronic pain, one of the most fundamental tasks of medicine, is often not satisfactorily achieved. Cannabinoid receptor 1 (CB1R) was identified as a promising target for pain therapy. We have previously described modulation of C...

Neurosciences (including psychophysiology)

  • 2021 - 2023
    • •
  • 5 901 tis. Kč
    • •
  • 5 901 tis. Kč
    • •
  • GA ČR
Project

Role of the orbitofrontal cortex, and its modulation by endocannabinoids, in social withdrawal in schizophrenia (GA22-06943S)

symptoms of the disease, resulted from a lack of cannabinoid CB1 receptor stimulation by cannabinoids. In this project, we will combine in vivo electrophysiology and behavioral......

Neurosciences (including psychophysiology)

  • 2022 - 2024
    • •
  • 9 183 tis. Kč
    • •
  • 9 183 tis. Kč
    • •
  • GA ČR
Project

Methods of nanoencapsulation of bloactive substances for topical use in dermatovenerology (FV40186)

and on the basis of the results from individual laboratory tests, a smart cannabinoid database...

Dermatology and venereal diseases

  • 2019 - 2022
    • •
  • 18 226 tis. Kč
    • •
  • 12 459 tis. Kč
    • •
  • MPO
Project

Combination of new cannabinoids and advanced formulation methods for treatment of rheumatoid arthritis (NU22-08-00346)

(emulsion-based and cocrystals) containing strong CB2 agonist cannabinoids (cannabidiol...

Pharmacology and pharmacy

  • 2022 - 2025
    • •
  • 14 344 tis. Kč
    • •
  • 14 344 tis. Kč
    • •
  • MZ
Project

Role of proteins associated with Cannabinoid receptor CB1 in trafficking (IAA500390701)

The fine-tuning of synaptic transmission and synaptic plasticity is necessary for harmonious neuronal network activity. Our project is precisely aimed at understanding of the endogenous cannabinoid system at the molecular, cellular, pharmaco...

FH - Neurologie, neurochirurgie, neurovědy

  • 2007 - 2011
    • •
  • 7 899 tis. Kč
    • •
  • 7 899 tis. Kč
    • •
  • AV ČR
Project

Effects of perioperative opioid analgesia on circulating tumor cells in colorectal cancer multicenter randomized clinical trial (NV18-03-00470)

, including analysis of opioid and cannabinoid receptor subtypes in cancer tissue. 2. PRMT of opioid and cannabinoid receptor subtypes in cancer tissue.......

Oncology

  • 2018 - 2022
    • •
  • 15 056 tis. Kč
    • •
  • 14 993 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 25