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Multivalent glycopolymers as ligands of lectin-denoted biological targets (LTC17005)
Multivalent biocompatible polymeric conjugates with various defined carbohydrate epitopes will be synthesized. Carbohydrate structures will be prepared by chemoenzymatic methods using a range of mutant and native glycosidases of
CE - Biochemie
- 2017 - 2020 •
- 2 791 tis. Kč •
- 2 791 tis. Kč •
- MŠMT
Řešení projektu: 1. 6. 2017 - 15. 4. 2020
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo školství, mládeže a tělovýchovy
Cooperation of E-cadherin and cell surface carbohydrates in intercellular adhesivity (NM18)
This project aims to determine the contribution of E-cadherin and carbohydrates of the plasma membrane to aggregation properties of tumor cells.Monoclonal antibodies specific for Lex GSL from liver metastases will also be prepared.......
EB - Genetika a molekulární biologie
- 1998 - 2000 •
- 3 054 tis. Kč •
- 2 104 tis. Kč •
- MZ
Řešení projektu: 1. 1. 1998 - 1. 1. 2000
Uznané náklady
Podpora ze státního rozpočtu (69%)
Poskytovatel: Ministerstvo zdravotnictví
The selected aspects of molecular ecology of Lyme borreliosis (IAA6022001)
Protein-carbohydrate interactions are the example of noncovalent type of interactions which are taking place during transmission of infective agents by vectors transmitted infections. Project deals with the study of carbohydrate bin...
EE - Mikrobiologie, virologie
- 2000 - 2002 •
- 6 896 tis. Kč •
- 1 696 tis. Kč •
- AV ČR
Řešení projektu: 1. 1. 2000 - 1. 1. 2002
Uznané náklady
Podpora ze státního rozpočtu (25%)
Poskytovatel: Akademie věd České republiky
Low-carbohydrate diet in type 1 diabetes effects on glycemic control and islet autoimmunity (NU21-01-00085)
. As an intervention, the restriction of carbohydrate intake to less than 130 g/day (a.k.a. low-carbohydrate diet) is becoming an increasingly popular choice for many patients with T1D-carbohydrate on glycemia control (meas...
Endocrinology and metabolism (including diabetes, hormones)
- 2021 - 2025 •
- 14 435 tis. Kč •
- 14 435 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2021 - 31. 12. 2025
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Molecular defects of carbohydrate and lipid metabolism in the etiology of cardiovascular diseases (1P05OC064)
role of proteinkinase c (PKC) in regulation of metabolism of main energetic substrates of human hepatic cells, study of activation of individual isoforms of PKC in cell cultures Hep G2 by fatty acids and at different glucose concentration......
BO - Biofyzika
- 2005 - 2005 •
- 580 tis. Kč •
- 426 tis. Kč •
- MŠMT
Řešení projektu: 1. 1. 2005 - 1. 1. 2005
Uznané náklady
Podpora ze státního rozpočtu (73%)
Poskytovatel: Ministerstvo školství, mládeže a tělovýchovy
Comprehensive metabolic and genetic assessment of the obese czech child population (NB6597)
Obesity leads already in childhood to pathological changes of the lipid and carbohydrate metabolism and this contributes to the development of risk factosr.In obese children serum values of the lipid and carbohydrate metabolism will...
FG - Pediatrie
- 2001 - 2003 •
- 3 288 tis. Kč •
- 3 130 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2001 - 1. 1. 2003
Uznané náklady
Podpora ze státního rozpočtu (95%)
Poskytovatel: Ministerstvo zdravotnictví
Metabolic flux analysis of carbohydrates and lipids in adipose tissue (LTAUSA17173)
Obesity is associated with a risk of developing metabolic syndrome that predisposes to the development of type 2 diabetes and cardiovascular diseases. Adipose tissue significantly affects the systemic processing of carbohydrates and lipids) ...
FB - Endokrinologie, diabetologie, metabolismus, výživa
- 2017 - 2019 •
- 2 284 tis. Kč •
- 2 284 tis. Kč •
- MŠMT
Řešení projektu: 1. 6. 2017 - 31. 12. 2019
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo školství, mládeže a tělovýchovy
Orthogonalisation of carbohydrate metabolism in bacterial chassis Pseudomonas putida EM42 for co-utilisation of lignocellulose-derived sugars (GJ19-06511Y)
Carbohydrates and aromatic compounds derived from renewable lignocellulose (plant biomass) can serve as cheap substrates for biotechnological production of valued chemicals. However, well-defined microbial platforms that could efficiently to...
Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation
- 2019 - 2021 •
- 5 442 tis. Kč •
- 5 442 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2019 - 31. 12. 2021
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Ruthenium-carbohydrate conjugates as cytostatic drugs with an enhanced selectivity to cancer cells (GA17-05838S)
ruthenium cytostatics with D-glucose (as well as other carbohydrates undergoing active connected to a carbohydrate framework. D-glucose derivatives monobenzylated in specific......
FD - Onkologie a hematologie
- 2017 - 2020 •
- 8 789 tis. Kč •
- 8 081 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2017 - 11. 12. 2020
Uznané náklady
Podpora ze státního rozpočtu (92%)
Poskytovatel: Grantová agentura České republiky
The effects of lowering dietary carbohydrates on health, exercise performance and wellbeing-related outcomes (GA18-08358S)
Intentional nutritional ketosis induced by the low carbohydrate diet is an intensively discussed topic of many scientific as well as non-scientific discussions-carbohydrate diet is more effective for weight loss and cardiovascular a...
Sport and fitness sciences
- 2018 - 2021 •
- 4 681 tis. Kč •
- 4 681 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2018 - 31. 12. 2021
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
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