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6 598 (0,139s) •

Project

Molecular mechanisms of regulation and function of autophagy in adaptation and longevity of U cell subpopulation of differentiated yeast colonies (LD15129)

The aim of the project is to bring new knowledge regarding function and regulation of autophagy in cells of differentiated yeast colonies, namely i) new findings a role in the regulation of autophagy in differentiated colon...

EB - Genetika a molekulární biologie

  • 2015 - 2017
    • •
  • 1 593 tis. Kč
    • •
  • 1 593 tis. Kč
    • •
  • MŠMT
Project

Disp3 A potential role in the self renewal and differentiation of neural stem cells (GA204/09/1905)

1. What is the role DISP3 in self-renewal and differentiation of neural stem cells? 2. Is there a correlation between the expression DISP3 and pathogenesis of brain tumors? 3. What is the impact of deregulated expression DISP3 on th...

EB - Genetika a molekulární biologie

  • 2009 - 2011
    • •
  • 4 017 tis. Kč
    • •
  • 4 017 tis. Kč
    • •
  • GA ČR
Project

Animal cell physiology (GD305/03/H148)

Study of cell physiology is a basic tool leading to knowledge in biomedical research. It combines modern methodological approaches using isolated cells and cell populations with the aim of understanding processes o...

ED - Fyziologie

  • 2003 - 2007
    • •
  • 16 217 tis. Kč
    • •
  • 16 217 tis. Kč
    • •
  • GA ČR
Project

The physiology of calcium signalling in human embryonic stem cell-derived neuronal precursors (GAP304/11/2373)

Human embryonic stem cell-derived neural precursors (hESC-NPs) are considered to be a promising tool for cell replacement therapy in CNS injuries and neurodegenerative-NPs. Using CCTL14 hESC-NPs we aim to characterize the physio...

ED - Fyziologie

  • 2011 - 2013
    • •
  • 6 561 tis. Kč
    • •
  • 6 561 tis. Kč
    • •
  • GA ČR
Project

The role of microRNA in cell cycle regulation and differentiation of human embryonic stem cell-derived neural stem cells. (GJ15-18316Y)

embryonic stem cell (hESC) physiology and are likely to regulate key stem cell self-renewal and differentiation with regulation of cell cycle and DNA damage. Here we aim to study the role of miRNA in ...

EB - Genetika a molekulární biologie

  • 2015 - 2017
    • •
  • 3 986 tis. Kč
    • •
  • 3 986 tis. Kč
    • •
  • GA ČR
Project

Molecular mechanisms of the cell proliferation and differentiation (GD204/08/H054)

of the cell proliferation and differentiation. Identification and comparison of molecular, differentiation and programmed cell death of cancer cells and (iv) bioinformaticswill result on collaboration of ...

EB - Genetika a molekulární biologie

  • 2008 - 2011
    • •
  • 17 297 tis. Kč
    • •
  • 17 297 tis. Kč
    • •
  • GA ČR
Project

Changes of the cytoskeleton in tumour cell lines during induced apoptosis in relation to different stages of differentiation (GA304/00/0403)

Apoptosis, a programmed cell death, is worth of study not only as aform of physiological cell death but also as a promising approach to the casual theraphy the apoptosis is modulated in differentiated cells

EA - Morfologické obory a cytologie

  • 2000 - 2002
    • •
  • 1 520 tis. Kč
    • •
  • 1 120 tis. Kč
    • •
  • GA ČR
Project

The role of vimentin in the monocyte/macrophage differentiation pathway (GP301/03/D022)

Significant changes in cellular morphology and physiology are connected with differentiation of hematopoietic cells. Namely, changes in amount, structure and localization of amount, structure and localization of vimentin du...

EB - Genetika a molekulární biologie

  • 2003 - 2006
    • •
  • 730 tis. Kč
    • •
  • 730 tis. Kč
    • •
  • GA ČR
Project

Novel physiological functions of apoptotic pathway components in hard tissue cells (GA16-18430S)

double role important for cell fate. Fas signalling pathway is critical for apoptosis, but recent results suggest also a role in cell differentiation. Caspases, as apoptosis previous research which identified novel phy...

ED - Fyziologie

  • 2016 - 2018
    • •
  • 4 653 tis. Kč
    • •
  • 4 653 tis. Kč
    • •
  • GA ČR
Project

Role of mitochondrial ROS signals in the development of the unicellular parasite Trypanosoma brucei (GA22-34480S)

molecules that inform the rest of the cell about the energetic and metabolic status of the mitochondria. Despite mROS signaling being instrumental for cells deciding to execute various cellular fates, it remains unclear how phy...

Cell biology

  • 2022 - 2022
    • •
  • 3 049 tis. Kč
    • •
  • 3 049 tis. Kč
    • •
  • GA ČR
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